Search results for "Developmental neuroscience"
showing 10 items of 360 documents
Child personality characteristics and selection into long-term unemployment in Finnish and Swedish longitudinal samples
2003
The main aim of the present study was to test a model of selection into long-term unemployment obtained for a sample of 36-year-old Finns (Kokko, Pulkkinen, & Puustinen, 2000) to see whether it similarly explained long-term unemployment among 26- to 27-year-old Finns and Swedes. The participants were drawn from two ongoing longitudinal studies: the Jyväskylä Longitudinal Study of Personality and Social Development (conducted in Finland) and the Individual Development and Adaptation study (conducted in Sweden). At both ages, that is 36 and 26–27, low education was related to long-term unemployment, and explained by personality characteristics in middle childhood, such as low self-contro…
Sociometric status of young adults: Behavioural correlates, and cognitive-motivational antecedents and consequences
2001
A cross-lagged longitudinal study was carried out to investigate whether social reaction styles and loneliness serve as antecedents and consequences of sociometric status among young adults. Behavioural correlates of sociometric status were also studied. Questionnaires measuring sociometric ratings, social reaction styles, loneliness, and group atmosphere were ”lled in by 154 students one week after starting at a new school, then half a year later, and ”nally, one year later. In Measurement 2, the participants’ social behaviour was rated by their classmates. The results indicated that social reaction styles, feelings of loneliness, and satisfaction with the group atmosphere prospectively p…
Situation-specificity of children's social goals: Changing goals according to changing situations?
2007
Children's agentic and communal goals were examined in hypothetical conflict, group entry, victimization, and positive situations ( N = 310, 11—13 years). Multilevel modeling was used to separate the variation in goals to the between- and within- (i.e., situation-specific) individual levels. About half of the variation in goals was due to individual differences. Boys endorsed more agentic goals than girls. A positive perception of self was associated with more agentic goals, whereas a positive perception of peers was associated with high degrees of communal goals. In addition, agentic goals were associated with rejection, whereas communal goals were related to peer acceptance. Children aim…
Novel Immunomodulatory Markers Expressed by Human WJ-MSC: an Updated Review in Regenerative and Reparative Medicine.
2012
Mesenchymal (stromal) stem cells (MSC) are a broad class of stromal populations which are able to differentiate towards mature cell types, and do express molecules involved in immune modulation, tolerance induction and inflammation dampening. MSC can be virtually isolated from each adult organ, as well as from foetus-associated perinatal tissues. In particular, Wharton's jelly-derived MSC (WJ-MSC) bear all of these key properties, together with their ease of sourcing and lack of ethical issues. Cellular therapy is a key technique in regenerative medicine approaches, in particular for the treatment of diseases in which physiological processes of cellular repopulation are blocked by the under…
Motor imagery
2015
International audience; Before participating in a space mission, astronauts undergo parabolic-flight and underwater training to facilitate their subsequent adaptation to weightlessness. Unfortunately, similar training methods can't be used to prepare re adaptation to planetary gravity. Here, we propose a quick, simple and inexpensive approach that could be used to prepare astronauts both for the absence and for the renewed presence of gravity. This approach is based on motor imagery (MI), a process in which actions are produced in working memory without any overt output. Training protocols based on MI have repeatedly been shown to modify brain circuitry and to improve motor performance in h…
The effects of children’s reading skills and interest on teacher perceptions of children’s skills and individualized support
2015
This study examined the effects of children’s reading skills and interest in reading-related tasks on teacher perceptions of children’s literacy skills (reading and spelling) and the respective individualized support for children during the first two years of formal schooling. The participants were 334 children and their classroom teachers. Identical measures were administered at three time points (at the beginning of Grade 1 and at the end of Grades 1 and 2). Children’s reading skills were assessed with the word reading fluency test, and their interest in reading was assessed with self-reports. Also, teachers evaluated each child’s level of reading and spelling skills and reported the lev…
Neurogenesis and Neuronal Regeneration in the Adult Reptilian Brain
2002
Evidence accumulated over the last few decades demonstrates that all reptiles examined thus far continue to add neurons at a high rate and in many regions of the adult brain. This so-called adult neurogenesis has been described in the olfactory bulbs, rostral forebrain, all cortical areas, anterior dorsal ventricular ridge, septum, striatum, nucleus sphericus, and cerebellum. The rate of neuronal production varies greatly among these brain areas. Moreover, striking differences in the rate and distribution of adult neurogenesis have been noted among species. In addition to producing new neurons in the adult brain, lizards, and possibly other reptiles as well, are capable of regenerating larg…
CRMP-4 expression in the adult cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica.
2002
The control of neuritogenesis is crucial for the development, maturation and regeneration of the nervous system. The collapsin response-mediated protein 4 (CRMP-4) is a member of a family of proteins that are involved in neuronal differentiation and axonal outgrowth. In rodents, this protein is expressed in recently generated neurons such as some granule neurons of the dentate gyrus, as well as in certain differentiated neurons undergoing neurite outgrowth or synaptogenesis during adulthood. Since CRMP-4 protein appears to be highly conserved throughout the evolutionary scale, we have used immunocytochemistry to study its distribution in the lizard cerebral cortex. We have found pronounced …
The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI
2009
Following severe traumatic brain injury (TBI), a complex interplay of pathomechanism, such as exitotoxicity, oxidative stress, inflammatory events, and mitochondrial dysfunction occurs. This leads to a cascade of neuronal and axonal pathologies, which ultimately lead to axonal failure, neuronal energy metabolic failure, and neuronal death, which in turn determine patient outcome. For mild and moderate TBI, the pathomechanism is similar but much less frequent and ischemic cell death is unusual, except with mass lesions. Involvement of mitochondria in acute post-traumatic neurodegeneration has been extensively studied during the last decade, and there are a number of investigations implicatin…
Long-term gene expression changes in the cortex following cortical ischemia revealed by transcriptional profiling
2006
Cerebral ischemia evokes changes in gene expression time-dependently after the ischemic event. Most studies on transcriptional changes following ischemia have centered on relatively early postischemic time points, and detected multiple genes relevant to neuronal cell death. However, functional outcome after ischemia depends critically on adaptations of the postischemic brain. Plasticity may derive from network-inherent changes, or from the formation of new nerve cells in the CNS. We have screened for gene expression changes up to 3 weeks following a limited photothrombotic cortical insult in the rat sensorimotor cortex by using the sensitive restriction-mediated differential display (RMDD) …