Search results for "Diaporthe"

showing 2 items of 2 documents

Anti-inflammatory dihydroxanthones from a Diaporthe species

2021

Abstract In a search for anti-inflammatory compounds from fungi inhibiting the promoter activity of the small chemokine CXCL10 (Interferon-inducible protein 10, IP-10) as a pro-inflammatory marker gene, the new dihydroxanthone methyl (1R, 2R)-1,2,8-trihydroxy-6-(hydroxymethyl)-9-oxo-2,9-dihydro-1H-xanthene-1-carboxylate (2) and the previously described dihydroxanthone AGI-B4 (1) were isolated from fermentations of a Diaporthe species. The structures of the compounds were elucidated by a combination of one- and two-dimensional NMR spectroscopy, mass spectrometry, and calculations using density functional theory (DFT). Compounds 1 and 2 inhibited the LPS/IFNγ induced CXCL10 promoter activity …

Chemokinegenetic structuresmedicine.drug_classClinical BiochemistryInflammation01 natural sciencesBiochemistryMarker geneAnti-inflammatory03 medical and health sciencesDiaporthemedicineCXCL10STAT1Molecular Biology030304 developmental biology0303 health sciencesbiology010405 organic chemistryChemistryTransfectionbiology.organism_classificationMolecular biology0104 chemical sciencesbiology.proteinmedicine.symptomBiological Chemistry
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First Report of Diaporthe eres Associated with Cane Blight of Grapevine (Vitis vinifera) in Italy

2016

In March 2014, in a ‘Trebbiano’ vineyard in the province of Florence (Tuscany, Italy), 15% of the grapevines (Vitis vinifera L.) showed 1-year old canes with bleached areas, sometimes surrounded by dark margins, irregular dark blotches, and several dead buds. Canes were covered by black pycnidia, and occasionally cracks on the cortex were evident. Woody tissues under the bark were necrotic and canes broke easily. Fifteen symptomatic canes were collected from different vines and cane segments of 20 cm length were placed in a moist chamber and incubated at 25°C. After 72 h, a cream-white cirri mass of conidia was observed from pycnidia and it was plated onto potato dextrose agar (PDA) plates.…

0301 basic medicinebiologySettore AGR/12 - Patologia VegetalePlant Science030108 mycology & parasitologybiology.organism_classification03 medical and health sciencesBotanyBlightDiaporthe eresVitis vinifera Cane Blight Diaporthe eres first reportCaneVitis viniferaAgronomy and Crop SciencePlant Disease
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