Search results for "Diastole"
showing 10 items of 173 documents
Computerized estimation of quality standards for the X-ray densitometric assessment of myocardial perfusion
2003
The densitometric evaluation of heart-phase-gated digital subtraction coronary angiograms derives different parameters which provide information about coronary blood flow, myocardial perfusion, and coronary flow reserve: appearance time, rise time, mean ascending time, and maximum intensity. The reliability and reproducibility of these measurements and of the derived parameters were investigated. Four digital subtraction coronary angiograms were obtained in ten patients, including two baseline measurements and two measurements under hyperemia induced by papaverine ic. Different reproducibility results were found for the parameters, depending on the heart phase of the densogram (diastolic be…
Diastolic dysfunction and central obesity related hypertension: role of trasforming growth factor beta-1
2004
Abstract P-368 Key Words: Diastolic Dysfunction, Obesity Related Hypertension, Trasforming Growth Factor beta-1
Sympathetic Overactivity and 24-Hour Blood Pressure Pattern in Hypertensives with Chronic Renal Failure
1995
In order to assess the activity of the sympathetic system and to evaluate the 24-h blood pressure pattern in hypertensives with chronic renal failure (CRF), 12 CRF patients and 16 essential hypertensives (EHs) were studied. In all subjects, plasma samples for catecholamines and renin activity were obtained both in the basal condition and after standing, and 24-h blood pressure monitoring (ABPM) was performed. The 24-h mean blood pressure results were quite similar between CRFs and EHs. In 50% of the CRFs, ABPM showed a nighttime decrease in diastolic BP (DBP) greater than 10%, while in the remaining 50% the ABPM indicated a nondipper blood pressure pattern. Of the 16 EHs, 4 had a nighttime …
ESH position paper: renal denervation - an interventional therapy of resistant hypertension
2012
Experts from the European Society of Hypertension prepared this position paper in order to summarize current evidence, unmet needs and practical recommendations on the application of percutaneous transluminal ablation of renal nerves [renal denervation (RDN)] as a novel therapeutic strategy for the treatment of resistant hypertension. The sympathetic nervous activation to the kidney and the sensory afferent signals to the central nervous system represent the targets of RND. Clinical studies have documented that catheter-based RDN decreases both efferent sympathetic and afferent sensory nerve traffic leading to clinically meaningful systolic and diastolic blood pressure (BP) reductions in pa…
Umbilical artery blood flow velocity waveforms during variable decelerations of the fetal heart rate
1991
Blood flow velocities of the umbilical arteries were measured by Doppler ultrasonography during variable decelerations of the fetal heart rate. The flow velocity waveforms, being normal between uterine contractions, showed either an unchanged flow velocity waveform with an exclusive fetal heart rate effect on end-diastolic velocities or a rapid change to absent and reverse diastolic flow during the decelerations, indicating an abrupt increase in placental resistance with a halt in placental perfusion. Computer-aided reconstruction of the fetal heart rate curve revealed the exact temporal relationship between the reduction of umbilical artery perfusion and deceleration of fetal heart rate. W…
Systemic pulsatile pressure in type II endoleaks after stent grafting of experimental abdominal aortic aneurysms.
2003
Purpose: To investigate pressure and maximum rate of rise of systolic pressure (peak dP/dt) in completely excluded aneurysms and endoleaks to determine the hemodynamic impact of endoleaks. Methods: In mongrel dogs (n = 36) experimental aneurysms were created by insertion of a patch (portion of rectus abdominis muscle sheath) into the infrarenal aorta. In group I (n = 18), all aortic branches of the aneurysm were ligated and all aneurysms were completely excluded by stent grafts. Group II (n = 18) consisted of aneurysms with patent aortic side branches that represented sources of endoleaks. One week (n = 12), six weeks (n = 12), and six months (n = 12) after stent grafting, hemodynamic measu…
Effects of long-term lifestyle and high-intensity interval training intervention on blood pressure reduction in patients with abdominal obesity
2013
Purpose: The aims of this study were: 1) to study the impact of a combined long-term lifestyle and high-intensity interval training (HIIT) intervention on blood pressure (BP) in patients with abdominal obesity; 2) To document BP reduction responses according to the European Society of Hypertension BP classification. Methods: 105 patients with abdominal obesity (age: 53±10 yrs; 32 men; waist circumference (WC): 112±13cm; systolic/diastolic (SBP/DBP): 133±13/82±8 mmHg; 11% diabetics, 11% smokers, 68% with antihypertensive therapy) were retrospectively analyzed before and after a combined long-term lifestyle and HIIT program twice a week. Anthropometric measurements, cardiometabolic risk facto…
Management of Atrial Fibrillation Suppression in AF-HF Comorbidity Therapy (MASCOT) Trial
2003
Inter- [1,2], intra- [3,4], and atrioventricular [51(AV) dyssynchrony are not new concepts, but only recently have attempts been made to correct these disorders in an effort to treat heart failure (HF). A series of trials [6] has addressed partial or comprehensive cardiac resynchronization in patients with severe HF and evidence of cardiac dyssynchrony. Cardiac resynchronization should improve left ventricular (LV) performance; several trials [7-10] have demonstrated improvement in many hemodynamic parameters (LV and aortic pressure, shortening of mitral diastolic regurgitation, synchronized LV and atrial systole, LV volume, reduced myocardial oxygen consumption) and clinical end-points (qu…
The Heart in Fabry Disease – from Pathogenesis to Enzyme Replacement Therapy
2010
The cardiovascular involvement in Fabry disease is progressive, and accounts for one of the major reasons for abbreviated life expectancy and increased morbidity. The majority of patients develop signs and symptoms, related to heart failure and arrhythmias. Hypertrophic cardiomyopathy, in later stages combined with myocardial fibrosis, is one of the leading features. Both genders are affected, and females develop severe cardiac Fabry disease approximately 10–15 years later in life than male patients. Diastolic dysfunction and reduced longitudinal mid-wall related systolic function are the mechanical consequences of the myocardial and epithelial changes related to accumulation of the storage…
A prospective randomized clinical trial compared the effect of various types of local anesthetics cartridges on hypertensive patients during dental e…
2015
Objectives: To evaluate hemodynamic changes of blood pressure and heart rate on hypertensive patients undergoing tooth extraction using various types of local anesthesia (LA). Study Design: A prospective randomized clinical trial was conducted on 45 hypertensive patients who were divided equally into 3 parallel groups according to LA received. Group 1: Lidociane 2% with epinephrine 1: 80,000. Group 2: Prilocaine 3% with Felypressin 0.03 IU/ml. Group 3: Mepivacaine 3% plain. Inclusion criteria: hypertensive patients, under medical management with blood pressure ≤ 159/99. Exclusion criteria: Blood pressure ≥160 /100 and patients receiving β blockers. Negative aspiration was mandatory before t…