Search results for "Diene"

showing 10 items of 623 documents

CCDC 762079: Experimental Crystal Structure Determination

2010

Related Article: Duc Hanh Nguyen, H.Laureano, S.Juge, P.Kalck, J.-C.Daran, Y.Coppel, M.Urrutigoity, M.Gouygou|2009|Organometallics|28|6288|doi:10.1021/om900684w

((Borane)-diphenyl-((5H-benzo[b]phosphindol-5-yl)methyl)phosphine)-(eta^2^eta^2^-cycloocta-15-diene)-rhodium tetraphenylborateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 804806: Experimental Crystal Structure Determination

2013

Related Article: D.H.Nguyen, J.Bayardon, C.Salomon-Bertrand, S.Juge, P.Kalck, J.-C.Daran, M.Urrutigoity, M.Gouygou|2012|Organometallics|31|857|doi:10.1021/om2008265

(1-((lambda^5^-Boranyl(diphenyl)phosphoranyl)methyl)-25-diphenyl-1H-phosphole-HH'P)-(eta^2^eta^2^-cyclo-octa-15-diene)-rhodium tetrafluoroborateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 814708: Experimental Crystal Structure Determination

2011

Related Article: N.Khiri, E.Bertrand, M.-J.Ondel-Eymin, Y.Rousselin, J.Bayardon, P.D.Harvey, S.Juge|2010|Organometallics|29|3622|doi:10.1021/om100520u

(eta4-Cyclo-octa-15-diene)-((Sp)-(-)-(((1S2R)-2-(diphenylphosphinito)-1-methyl-2-phenylethyl)(methyl)amino)-(35-dimethyl-4-propoxy)phosphane)-rhodium tetrafluoroborate dichloromethane n-hexane solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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First titanium-catalyzed 1,4-hydrophosphination of 1,3-dienes

2010

International audience

010405 organic chemistryOrganic Chemistrychemistry.chemical_elementHomogeneous catalysisGeneral Chemistry[CHIM.CATA]Chemical Sciences/Catalysis010402 general chemistry01 natural scienceshomogeneous catalysisCatalysis0104 chemical sciencesCatalysis[ CHIM.CATA ] Chemical Sciences/CatalysisphosphineschemistryhydrophosphinationdienesOrganic chemistryHydrophosphinationtitaniumComputingMilieux_MISCELLANEOUSTitanium
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A new C12 alcohol identified as a sex pheromone and a trail-following pheromone in termites: the diene (Z,Z)-dodeca-3,6-dien-1-ol

2003

0028-1042 (Print) Journal Article; The diunsaturated C12 alcohol (Z,Z)-dodeca-3,6-dien-1-ol (dodecadienol) has been characterized by GC-MS and FTIR as a novel releaser pheromone in termites. This alcohol identified in Ancistrotermes pakistanicus (Termitidae, Macrotermitinae) possesses a double pheromonal function which again illustrates the chemical parsimony of termites compared with other social insects. In workers, dodecadienol elicits trail-following at a very low concentration (activity threshold at 0.1 pg/cm of trail); in male alates it induces trail-following at a low concentration (1-10 pg/cm) and sexual attraction at a higher concentration (about 1 ng). Traces of the monounsaturate…

0106 biological sciencesStereochemistryIsoptera/*physiologyLinoleic acidAlcoholAlateIsopteraTrail pheromone010603 evolutionary biology01 natural sciencesPheromonesMass Spectrometrychemistry.chemical_compoundOrganic chemistryAnimalsPheromones/analysis/chemical synthesis/*chemistrySex AttractantsSocial BehaviorEcology Evolution Behavior and Systematics[SDV.EE]Life Sciences [q-bio]/Ecology environmentDodecanol/*analogs & derivatives/analysis/chemical synthesis/*chemistrybiologyAlkadienes/analysis/chemical synthesis/*chemistryGeneral Medicinebiology.organism_classificationSex Attractants/*analysis/chemistryAlkadienes010602 entomologyTermitidaeINSECTEchemistryDodecanolSex pheromonePheromoneMacrotermitinae
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Experimental Introgression To Evaluate the Impact of Sex Specific Traits on Drosophila melanogaster Incipient Speciation

2019

AbstractSex specific traits are involved in speciation but it is difficult to determine whether their variation initiates or reinforces sexual isolation. In some insects, speciation depends of the rapid change of expression in desaturase genes coding for sex pheromones. Two closely related desaturase genes are involved in Drosophila melanogaster pheromonal communication: desat1 affects both the production and the reception of sex pheromones while desat2 is involved in their production in flies of Zimbabwe populations. There is a strong asymmetric sexual isolation between Zimbabwe populations and all other “Cosmopolitan” populations: Zimbabwe females rarely copulate with Cosmopolitan males w…

0106 biological sciences[SDV]Life Sciences [q-bio]polymorphismeQH426-47001 natural sciencesheptacosadieneCourtshipmâleSexual Behavior Animalhydrocarbon polymorphismgenetique des populationsMatingévolutionGenetics (clinical)media_commonpheromone production0303 health sciencesbiologyBehavior AnimalIncipient speciationdésaturaseWhite (mutation)Genetics of SexDrosophila melanogasterPhenotypeSex pheromoneAlimentation et Nutritioneuropean corn-borercourtshipFemaleDrosophila melanogasterpyrale du maisfemale receptivitymedia_common.quotation_subjecthydrocarbure cuticulairediffusion de phéromoneparade sexuelleIntrogressionréceptivité femelle03 medical and health sciencesQuantitative Trait HeritableSex Factorsmaledesaturase geneGenetic algorithmexpressionevolutionGeneticsFood and NutritionAnimalstricoseneMolecular Biologycuticular hydrocarbon;tricosene;heptacosadiene;european corn-borer;pheromone production;desaturase gene;male;courtship;hydrocarbon polymorphism;female receptivity;evolution;mutation;populations;expressionGenetic Association Studies030304 developmental biologygène[SDV.BDLR]Life Sciences [q-bio]/Reproductive Biologybiology.organism_classificationpopulations010602 entomologyEvolutionary biologyunion européennecuticular hydrocarbonmutation
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Efficacy and safety of Everolimus and Exemestane in hormone-receptor positive (HR+) human-epidermal-growth-factor negative (HER2−) advanced breast ca…

2017

Abstract Background The BOLERO-2 trial reported efficacy and safety of Everolimus (EVE) and Exemestane (EXE) combination in HR+ advanced breast cancer (ABC) patients. The BALLET trial further evaluated the safety of EVE-EXE in HR+ ABC patients, without reporting efficacy data. Aim of the EVA real-life study was to collect data of efficacy and safety of EVE-EXE combination in the clinical setting, as well as exploring efficacy according to EVE Dose-Intensity (DI) and to previous treatment with Fulvestrant. Patients and methods This study aimed to describe the outcome of ABC pts treated with EVE-EXE combination in terms of median duration of EVE treatment and ORR in a real-life setting. Resul…

0301 basic medicineOncologyReceptor ErbB-2chemistry.chemical_compoundErbB-20302 clinical medicineDose-intensityExemestane80 and overNeoplasm MetastasisFulvestrantAged 80 and overeducation.field_of_studyAdvanced breast cancer Dose-intensity Everolimus Fulvestrant Hormone-receptor positiveAdvanced breast cancer; Dose-intensity; Everolimus; Fulvestrant; Hormone-receptor positive; Adult; Aged; Aged 80 and over; Androstadienes; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Receptor ErbB-2; SurgeryGeneral MedicineMiddle AgedEverolimu030220 oncology & carcinogenesisAdvanced breast cancerFemaleAdvanced breast cancer; Dose-intensity; Everolimus; Fulvestrant; Hormone-receptor positive; SurgeryReceptormedicine.drugAdultmedicine.medical_specialtyPopulationSocio-culturaleBreast NeoplasmsHormone-receptor positive03 medical and health sciencesBreast cancerAdvanced breast cancer; Dose-intensity; Everolimus; Fulvestrant; Hormone-receptor positive; Adult; Aged; Aged 80 and over; Androstadienes; Breast Neoplasms; Everolimus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Receptor ErbB-2Internal medicinemedicineHumansEverolimusAdverse effecteducationAgedNeoplasm StagingGynecologyEverolimusFulvestrantbusiness.industryfungiCancermedicine.diseaseAndrostadienesClinical trial030104 developmental biologychemistrySurgerybusinessFollow-Up StudiesThe Breast
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Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation

2016

Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid with anti-inflammatory, antiviral and anti-cancer properties. Beneficial cardiovascular effects such as increased nitric oxide (NO) production through enhancement of endothelial NO synthase (eNOS) activity and upregulation of eNOS expression have been demonstrated for this compound. In the present study, immortalized human EA.hy 926 endothelial cells were incubated for up to 1 h with 1–100 µM BA and with the phosphatidylinositol-3-kinase (PI3K) inhibitors LY294002 and wortmannin, or the estrogen receptor (ER) antagonist ICI 182,780. Phosphorylation status of eNOS and total eNOS protein were analyzed by Western blotting us…

0301 basic medicinePharmaceutical ScienceEstrogen receptorPI3KAnalytical ChemistryWortmanninchemistry.chemical_compound0302 clinical medicineEnosDrug DiscoveryLY294002PhosphorylationFulvestrantLungbiologyEstradiolendothelial cellsReceptors EstrogenChemistry (miscellaneous)030220 oncology & carcinogenesisMolecular MedicinePhosphorylationSignal transductionPentacyclic TriterpenesWortmanninSignal Transductionestrogen receptormedicine.medical_specialtyNitric Oxide Synthase Type IIIMorpholinesArticleCell Linelcsh:QD241-44103 medical and health sciencesbetulinic acidlcsh:Organic chemistryInternal medicinemedicineAnimalsHumansPhysical and Theoretical ChemistryProtein kinase BPI3K/AKT/mTOR pathwayendothelial nitric oxide synthaseAktOrganic ChemistryFibroblastsbiology.organism_classificationMolecular biologyTriterpenesbetulinic acid; endothelial nitric oxide synthase; endothelial cells; estrogen receptor; PI3K; AktRatsAndrostadienes030104 developmental biologyEndocrinologychemistryGene Expression RegulationChromonesPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktMolecules
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CCDC 816417: Experimental Crystal Structure Determination

2017

Related Article: Dieter Schollmeyer, Heiner Detert|2017|Tetrahedron Lett.|58|843|doi:10.1016/j.tetlet.2017.01.040

112455-hexachloro-3-(dichloromethylene)penta-14-dieneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 684679: Experimental Crystal Structure Determination

2009

Related Article: H.Detert, D.Lenoir, H.Zipse|2009|Eur.J.Org.Chem.|2009|1181|doi:10.1002/ejoc.200801076

1234-Tetrachloro-5-(dichloromethylene)-13-cyclopentadieneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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