Search results for "Diffuse"
showing 10 items of 276 documents
Soil emissivity and reflectance spectra measurements
2009
We present an analysis of the laboratory reflectance and emissivity spectra of 11 soil samples collected on different field campaigns carried out over a diverse suite of test sites in Europe, North Africa, and South America from 2002 to 2008. Hemispherical reflectance spectra were measured from 2.0 to 14 microm with a Fourier transform infrared spectrometer, and x-ray diffraction analysis (XRD) was used to determine the mineralogical phases of the soil samples. Emissivity spectra were obtained from the hemispherical reflectance measurements using Kirchhoff's law and compared with in situ radiance measurements obtained with a CIMEL Electronique CE312-2 thermal radiometer and converted to emi…
The restoration and reuse of sacred spaces in historical architecture: the Church of the Santissimo Salvatore in Naro and the Church of Santa Maria d…
2015
Il contributo analizza due testimonianze dell’architettura barocca nella Sicilia centro-orientale e presenta una sintesi delle riflessioni sorte durante l’esecuzione delle indagini diagnostiche e l’elaborazione dei progetti di restauro. In particolare, la ricerca, che trova nello studio storico-archivistico il suo determinate incipit, si sviluppa mediante un percorso conoscitivo che integra l’analisi dello stato di conservazione, la diagnosi delle forme d’alterazione e la scelta delle tecniche di restauro compatibili. Al fine della conservazione si accosta la volontà di rivitalizzare le due chiese attraverso il riuso di alcuni ambienti con la destinazione a spazi espositivi. La catalogazion…
Dissecting the microenvironment of Splenic Marginal Zone Lymphoma and Diffuse Large B cell Lymphoma to find new stromal and immunological predictive …
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling
2022
Abstract Background Autoimmune disorders, including Systemic Lupus Erythematosus (SLE), are associated with increased incidence of hematological malignancies. The matricellular protein osteopontin (OPN) has been linked to SLE pathogenesis, as SLE patients show increased serum levels of OPN and often polymorphisms in its gene. Although widely studied for its pro-tumorigenic role in different solid tumours, the role of OPN in autoimmunity-driven lymphomagenesis has not been investigated yet. Methods To test the role of OPN in the SLE-associated lymphomagenesis, the SLE-like prone Faslpr/lpr mutation was transferred onto an OPN-deficient background. Spleen from Faslpr/lpr and OPN-/-Faslpr/lpr …
Quantitative Multispectral Imaging Differentiates Melanoma from Seborrheic Keratosis.
2021
Melanoma is a melanocytic tumor that is responsible for the most skin cancer-related deaths. By contrast, seborrheic keratosis (SK) is a very common benign lesion with a clinical picture that may resemble melanoma. We used a multispectral imaging device to distinguish these two entities, with the use of autofluorescence imaging with 405 nm and diffuse reflectance imaging with 525 and 660 narrow-band LED illumination. We analyzed intensity descriptors of the acquired images. These included ratios of intensity values of different channels, standard deviation and minimum/maximum values of intensity of the lesions. The pattern of the lesions was also assessed with the use of particle analysis. …
Diffuse and concentrated pollution control at watershed-scale: an Italian case study
2008
Renato Guttuso and Sicily. For awidespread museum of the master of Bagheria
2021
Il contributo propone un approfondimento sulla figura di Renato Guttuso, artista siciliano che occupa un posto di rilievo nel panorama della pittura europea del XX secolo, attraverso ladisamina delle sue opere presenti in Sicilia,svolta alla luce dei più aggiornati studi sul legame dell’artista con la sua terra d’origine. Oltre al Museo Guttuso, fondato a Bagheria grazie a un lascito dell’artista, e al Complesso Monumentale dello Steridi Palermo, dove recentemente il suo capolavoro internazionalmente noto La Vucciriaè stato oggetto di un nuovo allestimento, si contano numerose sul territori siciliano le testimonianze della sua ricerca multiforme, grazie alla presenza di diverse realtà istit…
Zenker's Diverticulum in Forestier Disease: Chance or Causality?
2021
Zenker's diverticulum is an acquired sac-like outpouching of the mucosa and submucosa layers originating at the pharyngoesophageal junction. The predominant symptom of Zenker's diverticulum is dysphagia. Videofluoroscopy confirms the diagnosis. Forestier disease is a clinical entity characterized by ossification of anterolateral vertebral ligament and anterior osteophyte formation along the anterolateral spinal column. Its etiopathogenesis remains unknown and common symptoms are dysphagia, dysphonia and airway obstruction. The objective of this study is to identify a pathophysiological correlation between Forestier disease and the onset of Zenker's diverticulum.A retrospective observational…
La Media Education nelle scuole palermitane: pratiche d’uso dei media e percezioni diffuse tra gli insegnanti
2009
Functional characterisation of the first HSP110 inhibitors.
2023
Heat shock proteins are molecular chaperones highly expressed in haematological malignancies. My laboratory has shown that the heat shock protein HSP110 is a new and important therapeutic target In colorectal cancer and in non-Hodgkin's lymphoma. As there were no existing inhibitors of HSP110, a screening strategy of a chemical library was carried out and allowed the identification of two molecules capable of specifically inhibiting the chaperone activity of HSP110. My thesis objective was to characterise and functionally validate these newly identified molecules in diffuse large cell B lymphomas. I have shown that one of these molecules limits the interaction of HSP110 with the SYK signall…