Search results for "Diol"
showing 10 items of 11756 documents
ERP and EOG responses elicited by deviant tones when presented with and without standard tones to reading subjects
2002
Event-related potentials (ERPs) and horizontal electro-oculograms (HEOGs) were recorded in 11 subjects to infrequently presented spatially deviant tones (oddball-deviants) embedded in a series of frequently presented standard tones and also to these deviant tones when presented without the standard tones (alone-deviants). Subjects were instructed to read a self-selected book during the stimulus presentation. The mismatch negativity (MMN), a component of the ERP, was elicited by the oddball-deviants, whereas ERPs to the alone-deviants were characterized by a prominent N1. In an additional counting condition (subjects counting the oddball-deviants), the MMN to the oddball-deviants was followe…
Effect of frontal lobe lesions on the recollection and familiarity components of recognition memory
2008
Single-process theories assume that familiarity is the sole influence on recognition memory with decisions being made as a continuous process. Dual-process theories claim that recognition involves both recollection and familiarity processes with recollection as a threshold process. Although, the frontal lobes of the brain play an important role in recognition memory, few studies have examined the effect of frontal lobe lesions on recollection and familiarity. In the current study, the nonverbal recognition memory of 24 patients with focal frontal lesions due to turnout or stroke was examined. Recollection and familiarity were estimated using the receiver operating characteristic (ROC) metho…
Limitations of the trail making test part-B in assessing frontal executive dysfunction.
2015
AbstractPart B of the Trail Making Test (TMT-B) is one of the most widely used neuropsychological tests of “executive” function. A commonly held assumption is that the TMT-B can be used to detect frontal executive dysfunction. However, so far, research evidence has been limited and somewhat inconclusive. In this retrospective study, performance on the TMT-B of 55 patients with known focal frontal lesions, 27 patients with focal non-frontal lesions and 70 healthy controls was compared. Completion time and the number of errors made were examined. Patients with frontal and non-frontal lesions performed significantly worse than healthy controls for both completion time and the number of errors.…
Cochlear origin of early hearing loss in vestibular schwannoma.
2007
Objective: To test whether early hearing loss (HL) is cochlear in origin in patients with vestibular schwannoma (VS). Study Design: Retrospective case review in an academic tertiary referral center. Methods: A group of 19 VS patients with normal/symmetrical hearing and a group of 20 VS patients with mild HL (threshold at any tested frequency better than 45 dB HL) on the tumor ear side. Differences of the amplitudes of the distortion products of otoacoustic emissions (DPOAEs) between the tumor ear and the nontumor ear were studied at frequencies of 1, 1.4, 2, 2.8, and 4 kHz. The Wilcoxon test was used to compare the ears for both groups and to test for possible differences in tumor size betw…
Factors Influencing Tinnitus Loudness and Annoyance
2006
Objective To evaluate the 2 major components of tinnitus severity, loudness and annoyance, and their degree of dependence on characteristics of tinnitus manifestation, history, and etiology. Design Cross-sectional survey performed during the first months of 2004. Setting Nonclinical population. Participants A total of 4995 members of the German Tinnitus League. Main Outcome Measures Comprehensive screening questionnaire, including the Klockhoff and Lindblom loudness grading system and the miniversion of the Tinnitus Questionnaire. Results A moderate correlation of 0.45 was found between tinnitus loudness and annoyance. Both factors were generally higher in men, those older than 50 years, th…
Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…
1992
In a previous paper, in which the experimental conditions of the present research are fully described (Parrot et al., this issue), heart rate (HR) was studied in 60 male and in 60 female subjects in response to a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), and an intermittent pink noise (R), all noises being emitted at the same LAeq = 75 dB for 15 min. Digital pulse level (PL) responses were concomitantly surveyed by the use of pulse oximetry, allowing continuous arterial oxygen saturation (SaO2) readings. An index of pulse reactivity (PRI) could be calculated. Arterial blood pressure was measured 7 times from the beginning to the end of each trial. At rest, within…
What happens when we get angry? Hormonal, cardiovascular and asymmetrical brain responses
2010
This study aimed to evaluate neuroendocrine and cardiovascular responses together with changes in brain asymmetry following an anger mood induction laboratory task. Previous research has shown an increase in heart rate and blood pressure when anger is experienced. Increased testosterone and decreased cortisol in response to anger and aggressive behavior have also been reported. With regard to asymmetrical frontal brain activity and emotion, the valence model links negative affect (as anger) to the right hemisphere while the motivational direction model links approach-related emotions (as anger) to the left hemisphere. From the subjective perception and from the neuroendocrine and cardiovasc…
Insulin resistance and oxidative stress in familial combined hyperlipidemia.
2007
Oxidative stress is associated with atherosclerosis. Familial combined hyperlipidemia (FCH) is considered as a human model of primary dyslipidemia and atherosclerosis frequently associated with insulin resistance (IR), but there are few data on its possible relation to oxidative stress. The objective of this study was to evaluate oxidative stress status using different markers in subjects with FCH assessing its possible correlation with anthropometric parameters and IR. This was a cross-sectional study. A cohort of 40 FCH patients (20 with IR (HOMAor=3.2) and 20 without IR (HOMA3.2)), and 20 healthy volunteers were included, all of them non-diabetic, normotensive and non-smokers. We measure…
Environmental exposure to dioxins and polychlorinated biphenyls reduce levels of gonadal hormones in newborns: Results from the Duisburg cohort study
2006
Abstract Background Endocrine dysfunction related to the hypothalamic–pituitary–thyroid (HPT) and/or the hypothalamic–pituitary–gonadal axis (HPG) is being discussed as underlying developmental adversity of polychlorinated dibenzo- p -dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs). This study was done to evaluate effects related to the HPG axis. Methods A birth-cohort study was initiated in the year 2000. Healthy mother–infant pairs were recruited in the industrialized city of Duisburg, Germany. Dioxins, dioxin-like PCBs and six indicator PCBs were measured in maternal blood during pregnancy and in maternal milk. Testosterone and estradiol levels were measured in m…
Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…
1992
This study aimed at comparing for their cardiovascular effects: a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), an intermittent pink noise (R). All noises were presented at the same LAeq = 75 dB for 15 min each. Some 120 subjects were divided into 8 subgroups of 15 subjects each: OM (men between 40 and 50 years of age), OF (women, same age range), YM (men, between 15 and 20 years of age), YF (women, same age range), AM (typically anxious men, 20–25 years of age), AF (typically anxious women, same age range), NM (typicall anxiety-free men, same age range), and NF (typically anxiety-free women, same age range). Heart rate (HR), digital pulse level, and arterial blood p…