Search results for "Dipeptidase"

showing 2 items of 52 documents

COVID-19 and obesity: links and risks

2020

Applicable to the fields of endocrinology, as well as for specialists in cardiovascular disease (CVD), obesity has numerous cardiometabolic unfavorable consequences. Obesity is by far the leading c...

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Endocrinology Diabetes and MetabolismPneumonia ViralMEDLINEseverityDiseasePeptidyl-Dipeptidase ACOVID-19; Obesity; mortality; prognosis; severityCOVID-19BetacoronavirusMetabolic DiseasesRisk FactorsPandemicHumansMedicineObesityIntensive care medicinePandemicsbiologySARS-CoV-2business.industryViral EpidemiologyCOVID-19biology.organism_classificationmedicine.diseaseObesitymortalityPneumoniaAngiotensin-Converting Enzyme 2prognosisCoronavirus InfectionsbusinessBetacoronavirus
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Substance P Serum Degradation in Complex Regional Pain Syndrome – Another Piece of the Puzzle?

2021

In a previous study, we demonstrated that the serum peptidase system might be less efficient in complex regional pain syndrome (CRPS). Since the neuropeptide substanc P (SP) contributes to inflammation in CRPS, we now investigated the metabolism of SP in CRPS specifically. An SP metabolism assay was performed in 24 CRPS patients, which constitute a subgroup of our previous investigation on BK degradation. In addition, we included 26 healthy controls (24 newly recruited plus 2 from our previous investigation), and 13 patients after limb trauma, who did not fulfil the CRPS diagnostic criteria (trauma controls, TC) were included. We adapted a thin layer chromatography assay (TLC) to quantify S…

medicine.medical_specialtyNeuropeptideBradykininInflammationSubstance PPeptidyl-Dipeptidase ASubstance PBradykininchemistry.chemical_compoundInternal medicinemedicineHumansNeprilysinbiologybusiness.industryAngiotensin-converting enzymemedicine.diseaseAnesthesiology and Pain MedicineEndocrinologyComplex regional pain syndromeNeurologychemistrybiology.proteinNeurology (clinical)medicine.symptombusinessComplex Regional Pain SyndromesEx vivoPeptide HydrolasesThe Journal of Pain
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