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Synthesis, Stability and Relaxivity of TEEPO-Met: An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging
2018
Cancer is a widespread and life-threatening disease and its early-stage diagnosis is vital. One of the most effective, non-invasive tools in medical diagnostics is magnetic resonance imaging (MRI) with the aid of contrast agents. Contrast agents that are currently in clinical use contain metals, causing some restrictions in their use. Also, these contrast agents are mainly non-specific without any tissue targeting capabilities. Subsequently, the interest has notably increased in the research of organic, metal-free contrast agents. This study presents a new, stable organic radical, TEEPO-Met, where a radical moiety 2,2,6,6-tetraethylpiperidinoxide (TEEPO) is attached to an amino acid, methio…
Compensation of Oxygen Transmittance Effects for Proximal Sensing Retrieval of Canopy–Leaving Sun–Induced Chlorophyll Fluorescence
2018
Estimates of Sun–Induced vegetation chlorophyll Fluorescence (SIF) using remote sensing techniques are commonly determined by exploiting solar and/or telluric absorption features. When SIF is retrieved in the strong oxygen (O 2 ) absorption features, atmospheric effects must always be compensated. Whereas correction of atmospheric effects is a standard airborne or satellite data processing step, there is no consensus regarding whether it is required for SIF proximal–sensing measurements nor what is the best strategy to be followed. Thus, by using simulated data, this work provides a comprehensive analysis about how atmospheric effects impact SIF estimations on proximal sensing, regarding: (…
Modeling mass transfer in fracture flows with the time domain-random walk method
2019
The time domain-random walk method was developed further for simulating mass transfer in fracture flows together with matrix diffusion in surrounding porous media. Specifically, a time domain-random walk scheme was developed for numerically approximating solutions of the advection-diffusion equation when the diffusion coefficient exhibits significant spatial variation or even discontinuities. The proposed scheme relies on second-order accurate, central-difference approximations of the advective and diffusive fluxes. The scheme was verified by comparing simulated results against analytical solutions in flow configurations involving a rectangular channel connected on one side with a porous ma…
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study
2023
Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial dysfunction and metabolic syndrome in mice. However, most short-term clinical trials conducted so far have not reported positive outcomes. Therefore, we aimed to determine whether long-term NR supplementation boosts mitochondrial biogenesis and metabolic health in humans. Twenty body mass index (BMI)–discordant monozygotic twin pairs were supplemented with an escalating dose of NR (250 to 1000 mg/day) for 5 months. NR improved systemic NAD + metabolism, muscle mitochondrial number, myoblast differentiation, and gut microbiota compos…
First measurement of the W-boson mass in run II of the Tevatron.
2007
7 pages, 4 figures.-- PACS nrs.: 14.70.Fm; 13.38.Be; 13.85.Qk.-- ISI Article Identifier: 000250140600014.-- ArXiv pre-print available at: http://arxiv.org/abs/0707.0085.-- et al.
Study of J/ψ Production in Jets
2017
The production of $J/\psi$ mesons in jets is studied in the forward region of proton-proton collisions using data collected with the LHCb detector at a center-of-mass energy of 13 TeV. The fraction of the jet transverse momentum carried by the $J/\psi$ meson, $z \equiv p_{\rm T}(J/\psi)/p_{\rm T}({\rm jet})$, is measured using jets with $p_{\rm T}({\rm jet}) > 20$ GeV in the pseudorapidity range $2.5 < \eta({\rm jet}) < 4.0$. The observed $z$ distribution for $J/\psi$ mesons produced in $b$-hadron decays is consistent with expectations. However, the results for prompt $J/\psi$ production do not agree with predictions based on fixed-order non-relativistic QCD. This is the first measurement o…
"Table 30" of "Search for long-lived particles produced in $pp$ collisions at $\sqrt{s}=13$ TeV that decay into displaced hadronic jets in the ATLAS …
2018
Barrel MS vertex efficiencies (in %) for baryogenesis $\chi \rightarrow \nu b \bar{b}$ benchmark samples ($m_{h}=125$ GeV). The vertex reconstruction efficiency is defined as the fraction of simulated LLP decays in the MS fiducial volume that match a reconstructed vertex ($\Delta R(\textrm{LLP,vertex}) = 0.4$) passing the baseline event selection and satisfying the vertex isolation criteria. A vertex is considered matched to a displaced decay if the vertex is within $\Delta R = 0.4$ of the simulated decay position. The MS vertex efficiency is parameterized as a function of the LLP decay position.
"Table 41" of "Search for long-lived particles produced in $pp$ collisions at $\sqrt{s}=13$ TeV that decay into displaced hadronic jets in the ATLAS …
2018
Endcap MS vertex efficiencies (in %) for baryogenesis $\chi \rightarrow \nu b \bar{b}$ benchmark samples ($m_{h}=125$ GeV). The vertex reconstruction efficiency is defined as the fraction of simulated LLP decays in the MS fiducial volume that match a reconstructed vertex ($\Delta R(\textrm{LLP,vertex}) = 0.4$) passing the baseline event selection and satisfying the vertex isolation criteria. A vertex is considered matched to a displaced decay if the vertex is within $\Delta R = 0.4$ of the simulated decay position. The MS vertex efficiency is parameterized as a function of the LLP decay position.
"Table 31" of "Search for long-lived particles produced in $pp$ collisions at $\sqrt{s}=13$ TeV that decay into displaced hadronic jets in the ATLAS …
2018
Barrel MS vertex efficiencies (in %) for baryogenesis $\chi \rightarrow cbs$ benchmark samples ($m_{h}=125$ GeV). The vertex reconstruction efficiency is defined as the fraction of simulated LLP decays in the MS fiducial volume that match a reconstructed vertex ($\Delta R(\textrm{LLP,vertex}) = 0.4$) passing the baseline event selection and satisfying the vertex isolation criteria. A vertex is considered matched to a displaced decay if the vertex is within $\Delta R = 0.4$ of the simulated decay position. The MS vertex efficiency is parameterized as a function of the LLP decay position.
"Table 33" of "Search for long-lived particles produced in $pp$ collisions at $\sqrt{s}=13$ TeV that decay into displaced hadronic jets in the ATLAS …
2018
Barrel MS vertex efficiencies (in %) for baryogenesis $\chi \rightarrow \tau\tau\nu$ benchmark samples ($m_{h}=125$ GeV). The vertex reconstruction efficiency is defined as the fraction of simulated LLP decays in the MS fiducial volume that match a reconstructed vertex ($\Delta R(\textrm{LLP,vertex}) = 0.4$) passing the baseline event selection and satisfying the vertex isolation criteria. A vertex is considered matched to a displaced decay if the vertex is within $\Delta R = 0.4$ of the simulated decay position. The MS vertex efficiency is parameterized as a function of the LLP decay position.