Search results for "Disc"
showing 10 items of 19256 documents
Water and Sodium in Heart Failure: A Spotlight on Congestion.
2014
Despite all available therapies, the rates of hospitalization and death from heart failure (HF) remain unacceptably high. The most common reasons for hospital admission are symptoms related to congestion. During hospitalization, most patients respond well to standard therapy and are discharged with significantly improved symptoms. Post-discharge, many patients receive diligent and frequent follow-up. However, rehospitalization rates remain high. One potential explanation is a persistent failure by clinicians to adequately manage congestion in the outpatient setting. The failure to successfully manage these patients post-discharge may represent an unmet need to improve the way congestion is …
Antiplatelet treatment in ischemic stroke treatment.
2009
Antiplatelets represent a diverse group of agents that share the ability to reduce platelet activity through a variety of mechanisms. Antithrombotic agents are effective in the secondary prevention of ischemic strokes. Most strokes are caused by a sudden blockage of an artery in the brain (called an ischaemic stroke) that is usually due to a blood clot. Immediate treatment with antiplatelet drugs such as aspirin may prevent new clots from forming and hence improve recovery after stroke. Several studies have evaluated the role of one antiplatelet agent, aspirin, in reducing stroke severity. The International Stroke Trial (IST) of 20,000 patients with acute stroke from other countries. In thi…
Determination of crown discoloration and fluorescence induced by different medications used in regenerative endodontic procedures: An ex vivo study
2021
Background Crown discoloration is an undesirable side effect of the use of triple antibiotic paste (TAP) in regenerative endodontic procedures (REPs). The aim of this ex vivo study was to assess the potential for tooth discoloration and induction of fluorescence associated with the use of TAP containing either doxycycline (DOX) or clindamycin (CLIN), and of calcium hydroxide (Ca(OH)2), by spectrophotometric analysis and confocal laser scanning microscopy (CLSM). Material and methods A total of forty single-rooted human teeth extracted by therapeutic indication were used. The root canals were enlarged using the step-back technique up to a K #80 file and were randomly divided into four experi…
Indomethacin treatment in amphotericin B induced nephrogenic diabetes insipidus.
1994
Nephrogenic diabetes insipidus (NDI) is a serious side effect of various drugs. Elevated renal prostaglandin E2 levels have been found in patients with lithium-induced NDI and have been implicated in the pathogenesis. We report the case of a patient who developed NDI following treatment with amphotericin B. Prostaglandin levels were elevated. Indomethacin had an antidiuretic effect and normalized prostaglandin levels.
A body weight loss- and health-promoting gut microbiota is established after bariatric surgery in individuals with severe obesity
2020
Obesity has reached an epidemic level worldwide, and bariatric surgery (BS) has been proven to be the most efficient therapy to reduce severe obesity-related comorbidities. Given that the gut microbiota plays a causal role in obesity development and that surgery may alter the gut environment, investigating the impact of BS on the microbiota in the context of severe obesity is important. Although, alterations at the level of total gut bacteria, total gene content and total metabolite content have started to be disentangled, a clear deficit exists regarding the analysis of the active fraction of the microbiota, which is the fraction that is most reactive to the BS. Here, active gut microbiota…
Efficacy of the portage early intervention programme ‘growing: birth to three’ for children born prematurely
2020
Findings are presented from a study examining the effects of the home-based intervention ‘Growing: Birth to Three’ (GBT) on children born prematurely at a regional hospital in Norway over a four-year period. Nineteen children received the intervention, while 17 children comprised the control group. Results indicate that GBT had a positive effect on development at 18 months, as measured by the Bayley Scale of Infant Development. However, by 36 months both the intervention and control groups were in the normal range on this measure. A post-test comparison of language performance at 36 months found significantly higher expressive language scores among children in the intervention group on the …
Transforming subjectivities in psychiatric care
2009
Accepted version of an article in the journal: Subjectivities. The definitive publisher-authenticated version: Transforming subjectivities in psychiatric care, Subjectivity, Vol. 27, 195–216 , 2009, Palgrave Macmillan is available online at: http://dx.doi.org/10.1057/sub.2009.6 This paper is based upon ethnographic fieldwork in a Norwegian psychiatric unit practicing a psycho-educational treatment of young adults diagnosed with schizophrenia. An aim of the programme is that patients learn to detect and monitor their 'symptoms' in order to obtain 'insight into their own illness', thus transforming themselves into self-governed and self-responsible subjects who are able to cope with life outs…
Brain event-related potentials to phoneme contrasts and their correlation to reading skills in school-age children
2017
Development of reading skills has been shown to be tightly linked to phonological processing skills and to some extent to speech perception abilities. Although speech perception is also known to play a role in reading development, it is not clear which processes underlie this connection. Using event-related potentials (ERPs) we investigated the speech processing mechanisms for common and uncommon sound contrasts (/ba/-/da/-/ga/ and /ata/-/at: a/) with respect to the native language of school-age children in Finland and the US. In addition, a comprehensive behavioral test battery of reading and phonological processing was administered. ERPs revealed that the children could discriminate betw…
Music Training Enhances Rapid Neural Plasticity of N1 and P2 Source Activation for Unattended Sounds
2012
Neurocognitive studies have demonstrated that long-term music training enhances the processing of unattended sounds. It is not clear, however, whether music training also modulates rapid (within tens of minutes) neural plasticity for sound encoding. To study this phenomenon, we examined whether adult musicians display enhanced rapid neural plasticity compared to non-musicians. More specifically, we compared the modulation of P1, N1, and P2 responses to standard sounds between four unattended passive blocks. Among the standard sounds, infrequently presented deviant sounds were presented (the so-called oddball paradigm). In the middle of the experiment (after two blocks), an active task was p…
Designing Environments to Enhance Physical and Psychological Benefits of Physical Activity: A Multidisciplinary Perspective.
2016
This article is part of the Topical Collection on Designing environments to enhance physical and psychological benefits of physical activity : a multi-disciplinary perspective.