Search results for "Disc"

Femminicidi a processo. Dati, stereotipi e narrazioni della violenza di genere

2021

Il volume espone i risultati di una ricerca sulle rappresentazioni del femminicidio in ambito giudiziario in Italia, illustrandone il quadro teorico, le scelte metodologiche, l’impianto analitico, gli strumenti. La tematica del potere e della diseguaglianza tra i sessi è analizzata attraverso le definizioni fornitene in ambito giuridico e nei codici penali, esplorandone i significati sociali e questionando i possibili ancoraggi politici ed economici, attraverso il modello del “campo giuridico” di Bourdieu quale luogo di espressione di una forza simbolica che contende il potere ad altri “campi sociali”. L’indagine empirica è condotta attraverso un triplice livello di approfondimento di natur…

The Nasal Epithelium as a Factory for Systemic Protein Delivery

2002

We have previously shown that recombinant Sendai virus (SeV) produces efficient in vivo airway epithelial gene transfer. The ability to produce therapeutic levels of circulating proteins following noninvasive gene transfer would have widespread clinical application. Here, we compared nose, lung, and skeletal muscle for the ability to produce circulating levels of the secreted mouse antiinflammatory cytokine interleukin-10 (IL10) following SeV-mediated gene transfer. High levels of serum IL10 were obtained from each site with a potency order of lung > nose > muscle for a given viral titer. Serum levels from each site were within the likely required range for anti-inflammatory effects. The co…

Clathrin- and Caveolin-Independent Entry of Human Papillomavirus Type 16—Involvement of Tetraspanin-Enriched Microdomains (TEMs)

2008

BACKGROUND: Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molecule seems to be involved in virus uptake. Depending on the papillomavirus subtype, it has been reported that entry occurs by clathrin- or caveolin-mediated mechanisms. Regarding human papillomavirus type 16 (HPV16), the primary etiologic agent for development of cervical cancer, clathrin-mediated endocytosis was described as infectious entry pathway. METHODOLOGY/PRINCIPAL FINDINGS: Using immunofluorescence and infection studies we show in contra…

Tumor targeting of baculovirus displaying a lymphatic homing peptide.

2008

Background Tumor-associated cells and vasculature express attractive molecular markers for site-specific vector targeting. To attain tumor-selective tropism, we recently developed a baculovirus vector displaying the lymphatic homing peptide LyP-1, originally identified by ex vivo/in vivo screening of phage display libraries, on the viral envelope by fusion to the transmembrane anchor of vesicular stomatitis virus G-protein. Methods In the present study, we explored the specificity and kinetics of viral binding and internalization as well as in vivo tumor homing of the LyP-1 displaying virus to elucidate the applicability of baculovirus for targeted therapies. Results We demonstrated that th…

Regularity for nonlinear stochastic games

2015

We establish regularity for functions satisfying a dynamic programming equation, which may arise for example from stochastic games or discretization schemes. Our results can also be utilized in obtaining regularity and existence results for the corresponding partial differential equations. peerReviewed

I look but do I see? : the application of visual design grammar in an introductory image analysis discussion course

2004

Cluster visual field progression and its relationship with optic disc changes

2015

Purpose Glaucoma diagnosis and follow up of progression is often based on structural and functional assessments. This study aimed to assess clustered progression and evaluate its correlation with the corresponding disc changes (RA sectors) obtained from HRT examinations. Methods 51 eyes from OHT and glaucoma patients with a minimum of 5 reliable visual ᴀ밄eld tests (HFA II i 24-2) and HRT with a follow-up >4 years were analyzed retrospectively. Linear regression of clusters deᴀ밄ned by the Glaucoma Hemiᴀ밄eld Test (GHT) was performed based on the mean threshold in each cluster. Global and sectoral rates of change in RAs were assessed and correlated with functional clustered measures. Cluste…

Event-related potentials to task-irrelevant changes in facial expressions

2009

Abstract Background Numerous previous experiments have used oddball paradigm to study change detection. This paradigm is applied here to study change detection of facial expressions in a context which demands abstraction of the emotional expression-related facial features among other changing facial features. Methods Event-related potentials (ERPs) were recorded in adult humans engaged in a demanding auditory task. In an oddball paradigm, repeated pictures of faces with a neutral expression ('standard', p = .9) were rarely replaced by pictures with a fearful ('fearful deviant', p = .05) or happy ('happy deviant', p = .05) expression. Importantly, facial identities changed from picture to pi…

Género y enfermedad en la visualidad artística del fin de siglo español (1889-1921)

2022

La introducción de la modernidad artística en España en la segunda mitad del siglo XIX hizo de la enfermedad un tema que se trasladó a la visualidad artística. A pesar de arrastrarse algunos asuntos anclados en la tradición, los parámetros de representación en torno a lo patológico se renovaron, y las imágenes gestadas en este contexto reflejan muchos de los cambios acontecidos a nivel tecnológico, científico y social, enlazando con el ideario del progreso burgués. Ante la inminente llegada del fin de siglo, el tema de la enfermedad toma un nuevo rumbo en relación a otros discursos visuales que integran la imagen de la mujer y del hombre enfermos. Lo patológico se carga, en este momento, de…

Disciplinamiento social y vida cotidiana en la época de la confesionalización (1564-1665)

2018

Descripción del trabajo de investigación doctoral