Search results for "Disks"

showing 10 items of 118 documents

First M87 Event Horizon Telescope Results. I. the Shadow of the Supermassive Black Hole

2019

When surrounded by a transparent emission region, black holes are expected to reveal a dark shadow caused by gravitational light bending and photon capture at the event horizon. To image and study this phenomenon, we have assembled the Event Horizon Telescope, a global very long baseline interferometry array observing at a wavelength of 1.3 mm. This allows us to reconstruct event-horizon-scale images of the supermassive black hole candidate in the center of the giant elliptical galaxy M87. We have resolved the central compact radio source as an asymmetric bright emission ring with a diameter of 42 ± 3 μas, which is circular and encompasses a central depression in brightness with a flux rati…

010504 meteorology & atmospheric sciencesindividual (M87) [galaxies]Event horizonAstronomyblack hole physicsjets [galaxies]galaxies: individualAstrophysicshigh-resolution7. Clean energy01 natural sciencesPhoton sphereGeneral Relativity and Quantum Cosmologyaccretionsagittarius-a-asterisk010303 astronomy & astrophysicsgalactic-centerHigh Energy Astrophysical Phenomena (astro-ph.HE)Physicsradio-sourcesaccretion disksGalactic Centergrmhd simulations3. Good healthenergy-distributionsactive [galaxies]AnatomyAstrophysics - High Energy Astrophysical PhenomenaActive galactic nucleusAstrophysics::High Energy Astrophysical Phenomenagalaxies: activeFOS: Physical sciencesGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic Astrophysicsgalaxies: individual: M87galaxies: individual (M87)Cell and Developmental BiologyGeneral Relativity and Quantum Cosmology0103 physical sciences(M87)Astrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesEvent Horizon TelescopeSupermassive black holeghz vlbi observationsfaraday-rotationAstronomy and Astrophysicsgalaxies: jetsAstrophysics - Astrophysics of GalaxiesBlack holeRotating black holeSpace and Planetary SciencegravitationAstrophysics of Galaxies (astro-ph.GA)advection-dominated accretion[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]ionized-gas
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DLG4-related synaptopathy: a new rare brain disorder

2021

Contains fulltext : 245031.pdf (Publisher’s version ) (Closed access) PURPOSE: Postsynaptic density protein-95 (PSD-95), encoded by DLG4, regulates excitatory synaptic function in the brain. Here we present the clinical and genetic features of 53 patients (42 previously unpublished) with DLG4 variants. METHODS: The clinical and genetic information were collected through GeneMatcher collaboration. All the individuals were investigated by local clinicians and the gene variants were identified by clinical exome/genome sequencing. RESULTS: The clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disorder, and attention deficit-hyp…

0301 basic medicineAutism Spectrum Disorder[SDV]Life Sciences [q-bio]030105 genetics & heredityBiology03 medical and health sciencesIntellectual DisabilityIntellectual disabilitymedicineMissense mutationHumansGlobal developmental delayExomeGenetics (clinical)GeneticsBrain DiseasesNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Brainmedicine.disease030104 developmental biologyPhenotypeRenal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11]Autism spectrum disorderNeurodevelopmental DisordersSynaptopathyDLG4Postsynaptic densityDisks Large Homolog 4 Protein
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Regulation of Dendritic Spine Morphology in Hippocampal Neurons by Copine-6.

2015

Dendritic spines compartmentalize information in the brain, and their morphological characteristics are thought to underly synaptic plasticity. Here we identify copine-6 as a novel modulator of dendritic spine morphology. We found that brain-derived neurotrophic factor (BDNF) - a molecule essential for long-term potentiation of synaptic strength - upregulated and recruited copine-6 to dendritic spines in hippocampal neurons. Overexpression of copine-6 increased mushroom spine number and decreased filopodia number, while copine-6 knockdown had the opposite effect and dramatically increased the number of filopodia, which lacked PSD95. Functionally, manipulation of post-synaptic copine-6 level…

0301 basic medicineDendritic spineVesicular Inhibitory Amino Acid Transport Proteinsdrug effects [Synapses]Tropomyosin receptor kinase BHippocampal formationgenetics [Carrier Proteins]pharmacology [Brain-Derived Neurotrophic Factor]Hippocampusmetabolism [Vesicular Inhibitory Amino Acid Transport Proteins]Mtap2 protein ratMice0302 clinical medicineNeurotrophic factorsdrug effects [Synaptic Vesicles]genetics [Nerve Tissue Proteins]Cells Culturedultrastructure [Neurons]NeuronsChemistryLong-term potentiationSynaptic Potentialsphysiology [Neurons]physiology [Dendritic Spines]Cell biologyultrastructure [Dendritic Spines]metabolism [Receptor trkB]Synaptic VesiclesFilopodiaultrastructure [Synaptosomes]Disks Large Homolog 4 ProteinMicrotubule-Associated ProteinsCognitive NeuroscienceDendritic Spinesmetabolism [Disks Large Homolog 4 Protein]Nerve Tissue Proteinsgenetics [Receptor trkB]03 medical and health sciencesCellular and Molecular NeuroscienceOrgan Culture Techniquesphysiology [Synaptic Vesicles]metabolism [Vesicular Glutamate Transport Protein 1]TrkB protein ratdrug effects [Synaptic Potentials]Synaptic vesicle recyclingAnimalsHumansReceptor trkBddc:610metabolism [Synaptosomes]metabolism [Nerve Tissue Proteins]Viaat protein ratBrain-Derived Neurotrophic Factormetabolism [Microtubule-Associated Proteins]Rats030104 developmental biologygenetics [Synaptic Potentials]nervous systemcytology [Hippocampus]Synaptic plasticityultrastructure [Synapses]SynapsesVesicular Glutamate Transport Protein 1CPNE6 protein ratphysiology [Synapses]Carrier Proteins030217 neurology & neurosurgerymetabolism [Carrier Proteins]SynaptosomesCerebral cortex (New York, N.Y. : 1991)
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Verification of Radiative Transfer Schemes for the EHT

2020

Authors: Gold, Roman; Broderick, Avery E.; Younsi, Ziri; Fromm, Christian M.; Gammie, Charles F.; Mościbrodzka, Monika; Pu, Hung-Yi; Bronzwaer, Thomas; Davelaar, Jordy; Dexter, Jason; Ball, David; Chan, Chi-kwan; Kawashima, Tomohisa; Mizuno, Yosuke; Ripperda, Bart; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter; Asada, Keiichi; Azulay, Rebecca Baczko, Anne-Kathrin; Baloković, Mislav; Barrett, John; Bintley, Dan; Blackburn, Lindy; Boland, Wilfred; Bouman, Katherine L.; Bower, Geoffrey C.; Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broguiere, Dominique; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chatterjee, Koushik; Chatterjee, Shami; Chen, Ming-T…

1388010504 meteorology & atmospheric sciencesGeodesicGeneral relativityEvent horizonAstronomyAstrophysics::High Energy Astrophysical PhenomenaKerr metric15947901 natural sciencesRelativistic disks739Relativity0103 physical sciencesRadiative transferRadiative transfer1769Radio astronomy010303 astronomy & astrophysicsComputingMilieux_MISCELLANEOUS0105 earth and related environmental sciencesVery long baseline interferometryPhysicsEvent Horizon Telescope[PHYS]Physics [physics]Supermassive black holeEvent horizons1335Astronomy and AstrophysicsBlack hole physics1393641Computational physicsBlack holeGeneral relativitySpace and Planetary Science1338[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]High energy astrophysics
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First M87 Event Horizon Telescope Results. VII. Polarization of the Ring

2021

Full list of authors: Akiyama, Kazunori; Algaba, Juan Carlos; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Benson, Bradford A.; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond; Boland, Wilfred; Bouman, Katherine L.; Bower, Geoffrey C.; Boyce, Hope Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broderick, Avery E.; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Chesler, Paul M.; Cho, Ilje; Christian, Pierre; Conway, John E.…

1663010504 meteorology & atmospheric sciences1346KinoAstrophysics - astrophysics of galaxiesAstronomyAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesGalaxy accretion disks01 natural sciencesAstrophysics - high energy astrophysical phenomena2033Galaxies: individual: M87 1278 1346 1769 1663 16 2033 1859 5620103 physical sciencesPolarimetrySupermassive black holes1769010303 astronomy & astrophysicsAstronomy data modeling0105 earth and related environmental sciencesVery long baseline interferometryPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Active galactic nucleiGalaxies: individual: M871278F510ChatterjeeAstronomy and AstrophysicsCreative commons16562Low-luminosity active galactic nuclei13. Climate actionSpace and Planetary ScienceAstrophysics of Galaxies (astro-ph.GA)Fish <Actinopterygii>Radio interferometryHumanities1859
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Event Horizon Telescope imaging of the archetypal blazar 3C 279 at an extreme 20 microarcsecond resolution

2020

Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Open Access funding provided by Max Planck Society.--All authors: Kim, Jae-Young; Krichbaum, Thomas P.; Broderick, Avery E.; Wielgus, Maciek; Blackburn, Lindy; Gómez, José L.; Johnson, Michael D.; Bouman, Katherine L.; Chael, Andrew; Akiyama, Kazunori; Jorstad, Svetlana; Marscher, Alan P.; Issaoun, Sara; Janssen, Michael; Chan, Chi-kwan; Savolainen, Tuomas; Pesce, Dominic W.; Özel, Feryal; Alberdi, Antxon; Alef, Walt…

ACTIVE GALACTIC NUCLEIBrightnessActive galactic nucleusactive [Galaxies]Astrophysics::High Energy Astrophysical PhenomenaAstronomygalaxies: activeAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesSubmillimeter ArrayFLOWSSCALE CIRCULAR-POLARIZATION0103 physical sciencesVery-long-baseline interferometryBlazar010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsEvent Horizon Telescope[PHYS]Physics [physics]Jet (fluid)010308 nuclear & particles physicsAstronomy and AstrophysicsFLAREgalaxies: jetsindividual: 3C 279 [Galaxies]LONGVARIABILITYgalaxies: individual: 3C 279GAMMA-RAYQUASARS13. Climate actionSpace and Planetary Sciencetechniques: interferometricBrightness temperatureACCRETION DISKSinterferometric [Techniques]jets [Galaxies]RELATIVISTIC JETS[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astronomy & astrophysics
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QPOs expected in rotating accretion flows around a supermassive black hole

2007

It is well known that rotating inviscid accretion flows with adequate injection parameters around black holes could form shock waves close to the black holes, after the flow passes through the outer sonic point and can be virtually stopped by the centrifugal force. We numerically examine such shock waves in 2D accretion flows with 10−5 to 106 Eddington critical accretion rates around a supermassive black hole with 106 M. As the results, the luminosities show QPO phenomena with modulations of a factor 2–3 and with quasi-periods of a few to several hours.

Accretion accretion disks – black hole physics – galaxies: active – hydrodynamics – radiation mechanisms: thermal – shock waves
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Pulsating in Unison at Optical and X-Ray Energies: Simultaneous High Time Resolution Observations of the Transitional Millisecond Pulsar PSR J1023+00…

2019

PSR J1023+0038 is the first millisecond pulsar discovered to pulsate in the visible band; such a detection took place when the pulsar was surrounded by an accretion disk and also showed X-ray pulsations. We report on the first high time resolution observational campaign of this transitional pulsar in the disk state, using simultaneous observations in the optical (TNG, NOT, TJO), X-ray (XMM-Newton, NuSTAR, NICER), infrared (GTC) and UV (Swift) bands. Optical and X-ray pulsations were detected simultaneously in the X-ray high intensity mode in which the source spends $\sim$ 70% of the time, and both disappeared in the low mode, indicating a common underlying physical mechanism. In addition, o…

AccretionAccretion disks-pulsars: Individual (psr j1023+0038)-stars: Neutron-X-rays: Binaries010504 meteorology & atmospheric sciencesAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesAstrophysics01 natural sciencesSettore FIS/05 - Astronomia E AstrofisicaPulsarAccretion discMillisecond pulsar0103 physical sciencesAstrophysics::Solar and Stellar Astrophysics010303 astronomy & astrophysicsAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesHigh Energy Astrophysical Phenomena (astro-ph.HE)PhysicsAstrophysics::Instrumentation and Methods for AstrophysicsX-rayAstronomy and AstrophysicsTime resolutionAccretion (astrophysics)Space and Planetary ScienceVisible bandAstrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaThe Astrophysical Journal
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NuSTAR and NICER reveal IGR J17591-2342 as a new accreting millisecond X-ray pulsar

2018

We report the discovery by the Nuclear Spectroscopic Telescope Array (NuSTAR) and the Neutron Star Interior Composition Explorer (NICER) of the accreting millisecond X-ray pulsar IGR J17591-2342. Coherent X-ray pulsations around 527.4 Hz (1.9 ms) with a clear Doppler modulation were detected. This implies an orbital period of ∼8.8 h and a projected semi-major axis of ∼1.23 lt-s. With the binary mass function, we estimate a minimum companion mass of 0.42 M, obtained assuming a neutron star mass of 1.4[subscript ⊙] and an inclination angle lower than 60°, as suggested by the absence of eclipses or dips in the light curve of the source. The broad-band energy spectrum, obtained by combining NuS…

AccretionAstrophysics::High Energy Astrophysical Phenomenageneral [Pulsars]FOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesSpectral linelaw.inventionTelescopeX-rays: binariesSettore FIS/05 - Astronomia E AstrofisicaPulsarlow-mass [Stars]lawstars: low-mass0103 physical sciencesStars: low-maAstrophysics::Solar and Stellar Astrophysics010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Neutron Star Interior Composition Explorer010308 nuclear & particles physicsComputer Science::Information Retrievalaccretion disksneutron [Stars]Astronomy and AstrophysicsAstronomy and AstrophysicOrbital periodLight curveX-rays: binarieStars: neutronNeutron starPulsars: generalAccretion diskSpace and Planetary ScienceAccretion disksbinaries [X-rays]Astrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical Phenomena[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]X-ray pulsar
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X-shooter spectroscopy of young stars with disks. The TW Hydrae association as a probe of the final stages of disk accretion

2019

We investigate ongoing accretion activity in young stars in the TW Hydrae association (TWA, ~8-10 Myr), an ideal target to probe the final stages of disk accretion down to brown dwarf masses. Our sample comprises eleven TWA members with infrared excess, amounting to 85% of the total TWA population with disks, with spectral types between M0 and M9, and masses between 0.58 and 0.02 Msol. We employed homogeneous spectroscopic data from 300 to 2500 nm, obtained with X-shooter, to derive individual extinction, stellar parameters, and accretion parameters simultaneously. We then examined Balmer lines and forbidden emission lines to probe the physics of the star-disk interaction environment. We de…

AccretionOpen clusters and associations: individual: TWA010504 meteorology & atmospheric sciencesBrown dwarfFOS: Physical sciencesTechniques: spectroscopicAstrophysicsProtoplanetary diskStellar classification01 natural sciencesspectroscopic [Techniques]symbols.namesakeSettore FIS/05 - Astronomia E Astrofisicalow-mass [Stars]pre-main sequence [Stars]0103 physical sciencesStars: low-maTW HydraeQB Astronomy010303 astronomy & astrophysicsSolar and Stellar Astrophysics (astro-ph.SR)QC0105 earth and related environmental sciencesQBEarth and Planetary Astrophysics (astro-ph.EP)PhysicsInfrared excessBalmer seriesAstronomy and AstrophysicsDASAstrophysics - Astrophysics of GalaxiesAccretion (astrophysics)StarsQC PhysicsAstrophysics - Solar and Stellar AstrophysicsSpace and Planetary ScienceAccretion diskAstrophysics of Galaxies (astro-ph.GA)Accretion diskssymbolsStars: pre-main sequenceindividual: TWA [Open clusters and associations]Astrophysics - Earth and Planetary Astrophysics
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