Search results for "Disorder"

showing 10 items of 6405 documents

Tetralogy of Fallot as a Model to Study Cardiac Progenitor Cell Migration and Differentiation During Heart Development

2009

Tetralogy of Fallot (ToF) has long been considered a congenital disorder that occurs due to environmental alterations during gestation. Recently, several mutated genes have been discovered that are thought to be responsible for the malformations observed in ToF. These genetic mutations, which are microdeletions, are sporadic and are frequently also present in trisomy 21 patients. The ToF malformations can be lethal, but for the last 50 years, surgical repairs that place an artificial patch to repair the four features of ToF have improved the survival of patients with ToF. However, 0.5% to 6% of patients who survive after surgical repair of ToF die of sudden cardiac death caused by ventricul…

medicine.medical_specialtyOrganogenesisBiologyVentricular tachycardiaSudden cardiac deathHomeobox protein Nkx-2.5Cell MovementInternal medicinemedicineAnimalsHumansCell LineageCell ProliferationTetralogy of FallotHomeodomain ProteinsSurgical repairHeart developmentMyocardiumStem CellsGene Expression Regulation DevelopmentalCell DifferentiationToF Cardiac Stem Cellsmedicine.diseaseGATA4 Transcription Factormedicine.anatomical_structureVentricleMutationHomeobox Protein Nkx-2.5Tetralogy of FallotCardiologyCardiology and Cardiovascular MedicineTranscription FactorsCongenital disorderTrends in Cardiovascular Medicine
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Factors Associated With Psychological Disturbances During the COVID-19 Pandemic: Multicountry Online Study.

2021

Background Accumulating evidence suggests that the COVID-19 pandemic has negatively impacted the mental health of individuals. However, the susceptibility of individuals to be impacted by the pandemic is variable, suggesting potential influences of specific factors related to participants’ demographics, attitudes, and practices. Objective We aimed to identify the factors associated with psychological symptoms related to the effects of the first wave of the pandemic in a multicountry cohort of internet users. Methods This study anonymously screened 13,332 internet users worldwide for acute psychological symptoms related to the COVID-19 pandemic from March 29 to April 14, 2020, during the fi…

medicine.medical_specialtyOriginal Papermedia_common.quotation_subjectpandemicMEDLINECOVID-19globalMental healthPsychiatry and Mental healthOptimismposttraumatic stress disordergeneral psychological disturbanceCohortPandemicdepressionmedicineSocial mediaBig Five personality traitsPsychiatryPsychologyDepression (differential diagnoses)mental healthmedia_commonJMIR mental health
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Consumo de sustancias en jóvenes adultos con TDAH: comorbilidad y síntomas de inatención e hiperactividad/impulsividad

2016

Young adults with attention deficit hyperactivity disorder (ADHD) are at high risk of substance use (SU). The aims of the current study were: 1) to examine the use of alcohol, tobacco, marijuana and other illegal drugs by adults with and without ADHD; 2) to compare the oppositional, conduct, anxiety, depression, sleep and antisocial personality symptoms of ADHD adults with SU and ADHD adults without SU; 3) to examine the ability of ADHD symptoms and conduct problems to predict SU. A total of 93 young adults, 43 without ADHD and 50 with a childhood diagnosis of ADHD, who were part of the Spanish sample of the Multicenter ADHD Genetics (IMAGE) study, collaborated in a follow-up evaluation 10.…

medicine.medical_specialtyOriginal articleExternalizationlcsh:BF1-990substance useSubstance useAffect (psychology)behavioral disciplines and activitiesOppositional defiant disorderConduct disorderEx post facto study03 medical and health sciences0302 clinical medicinemental disordersmedicineAttention deficit hyperactivity disorderADHD0501 psychology and cognitive sciencesTDAHestudio ex post factoYoung adultex post facto studyPsychiatryDepression (differential diagnoses)conduct disorder05 social sciencesconsumo de sustanciasmedicine.diseaseComorbidity030227 psychiatryClinical Psychologylcsh:Psychologyoppositional defiant disordertrastorno de conductaAnxietytrastorno negativista desafiantemedicine.symptomSubstance usePsychology050104 developmental & child psychology
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Orthopedic-orthodontic treatment of the patient with Turner's syndrome: Review of the literature and case report.

2018

Aims Turner syndrome (TS) patients have phenotypical variable presentations and they are more susceptible to endocrine, auto-immune, and structural anomalies. Typical clinical characteristics are short stature and premature ovarian insufficiency. Patients with TS show a typical cranial-facial morphology with bi-maxillary bi-retrusion, high-arched palate, micrognathia, and class II malocclusion. Aim of our study is to present the orthopedic-orthodontic treatment approach of a young TS patient and data of stability after 7 years. Methods and results A careful analysis of anamnestic data was performed. After extraoral and intraoral examination, cephalometric measurements and examination of mod…

medicine.medical_specialtyPalatal Expansion TechniqueCephalometryRadiographyTurner SyndromeMalocclusion Angle Class IIPremature ovarian insufficiencyShort statureoral pathology; orthodontics; rare disorders; Dentistry (all)Orthodontics CorrectiveCraniofacial Abnormalities03 medical and health sciences0302 clinical medicine030225 pediatricsOral and maxillofacial pathologyTurner syndromeMedicineHumansrare disordersChildGeneral DentistryOrthodonticsorthodonticbusiness.industryElectromyography030206 dentistrymedicine.diseaseTurner's syndromeCombined Modality TherapyOrthopedic surgeryMasticatory MusclesDentistry (all)Femalemedicine.symptomMalocclusionoral pathologyorthodonticsbusinessSpecial care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
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Aberrant opioid use behaviour in advanced cancer.

2020

ObjectivesTo evaluate the presence of aberrant behaviour in a consecutive sample of patients with advanced cancer treated with opioids in a country like Italy, with its peculiar attitudes towards the use opioids. The second objective was to detect the real misuse of opioids in clinical practice.MethodsProspective observational study in two palliative care units in Italy in a period of 6 months. At admission the Edmonton Symptom Assessment Scale, the Memorial Delirium Assessment Scale, Brief Pain Inventory (BPI) and the Hospital Anxiety Depression Scale were measured. For detecting the risk of aberrant opioid use, the Screener and Opioid Assessment for Patients With Pain (SOAAP), the Opioid …

medicine.medical_specialtyPalliative careMedicine (miscellaneous)chronic conditionRisk Assessment03 medical and health sciences0302 clinical medicineInternal medicineNeoplasmscancerMedicineHumans030212 general & internal medicineBrief Pain InventoryPain MeasurementOncology (nursing)business.industryOpioid useCancerpain.General Medicinemedicine.diseaseOpioid-Related DisordersAdvanced cancerAnalgesics OpioidMedical–Surgical NursingOpioid030220 oncology & carcinogenesisDeliriumObservational studymedicine.symptombusinesshospital caremedicine.drugBMJ supportivepalliative care
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Soziale Phobie – eine im psychosomatischen Ambulanz- und Konsildienst unterdiagnostizierte Angsterkrankung?

2009

Social fears are common, whereas Social Phobia is diagnosed infrequently. Therefore, we compared the clinical diagnoses (ICD-10) in an outpatient and CL service of a psychosomatic university hospital to patients' self ratings in social fears on the Liebowitz Social Anxiety Scale (LSAS). Over the course of one year 688 patients could be characterized regarding their clinical diagnoses, LSAS-scores, symptom severity (SCL-90R) and psychosomatic complaints (GBB-24). Patients were assigned to three groups by their levels of social fears (LSAS). Social Phobia was diagnosed rarely by clinicians (5.5%), but generalized social fears (LSAS>60) were commonly reported by patients (14.6%). Patients with…

medicine.medical_specialtyPanic disorderLiebowitz social anxiety scalemedicine.diseasePhobic disorderPsychiatry and Mental healthClinical PsychologyDistressAmbulatory caremedicinePsychiatryPsychologyApplied PsychologyDepression (differential diagnoses)Anxiety disorderAgoraphobiaClinical psychologyPPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie
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Clinical utility of cognitive-behavioural treatment for panic disorder. results obtained in different settings: a research centre and a public mental…

2002

Cognitive-Behavioural programmes have become the treatment of choice for Panic Disorder (PD). However, although its effectiveness has been widely demonstrated, there are still some limitations regarding the possibility of offering this type of treatment to all panic sufferers. Some researchers are studying ways to make these programmes more available. This study deals with the application and testing of treatment programmes for PD in sites where patients usually look for help for their psychological problems, i.e. mental health care centres. Our work follows a strategy of benchmarking, and the results obtained after applying the treatment in habitual clinical contexts are compared with the …

medicine.medical_specialtyPanic disorderPanicCognitionBenchmarkingmedicine.diseaseMental healthUnit (housing)Clinical PsychologyResearch centremedicineMental health caremedicine.symptomPsychologyPsychiatryClinical Psychology & Psychotherapy
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Coffee and Anxiety

2015

Abstract This chapter discusses the effects of coffee consumption on anxiety response, taking into account vulnerability factors such as sex and genetics. In light of research concerning the effects of coffee on normal anxiety, and particularly research carried out in our laboratory, current knowledge can be summarized as follows: (1) men appear to be more sensitive to the effects of coffee than women; and (2) coffee can increase alertness in habitual consumers after acute deprivation, but not above the level of that observed in nonconsumers. In addition, we discuss clinical evidence of the varying sensitivity of anxiety disorder patients to the effects of coffee. The caffeine challenge tes…

medicine.medical_specialtyPanic disorderSocial anxietyPanicmedicine.diseaseVulnerability factorsAlertnesschemistry.chemical_compoundchemistrymedicineAnxietymedicine.symptomPsychiatryPsychologyCaffeineAnxiety disorder
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Somatosensory amplification in hypochondriasis and panic disorder

1999

The aim of this study is to explore the differences and similarities of Somatic Amplification (SA) in both panic and hypochondriasis disorders. An additional objective is to validate the Somatosensory Amplification Scale (SSAS) for use in our cultural context. For these purposes, 34 patients (17 with hypochondriasis and 17 with panic disorder; DSM-III-R criteria) completed the following questionnaires: SSAS, State–Trait Anxiety Inventory, Beck Depression Inventory, MMPI Hypochondriasis Scale, Illness Attitude Scales and Illness Behaviour Questionnaire. The SSAS showed a satisfactory internal consistency (Cronbach's α=0·83), and revealed two components: ‘Internal Stimulus Amplification’ and …

medicine.medical_specialtyPanic disorderSomatosensory amplificationBeck Depression InventoryPanicmedicine.diseasebehavioral disciplines and activitieshumanitiesClinical PsychologyMinnesota Multiphasic Personality InventoryCronbach's alphaInternal consistencymedicineAnxietymedicine.symptomPsychologyPsychiatryClinical psychologyClinical Psychology & Psychotherapy
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Possibilities and necessities of parenteral nutrition with amino acid mixtures.

1975

In recent years, there have been conclusive findings in the field of maintaining homeostasis following trauma, bleeding, nutritional and metabolic disturbances and infections. These findings can help save the lives of an increasing number of injured and sick by enlarging the therapeutic possibilities which have previously been unimaginable. This development has been made possible by the good cooperation of both basic research and clinical staff whose common aim was to achieve advances in this field of intensive care. The aim of the present study is to make a relevant theoretical and practical contribution to the widening possibilities and necessities in this field.

medicine.medical_specialtyParenteral NutritionProtein HydrolysatesMedicine (miscellaneous)HemorrhageBiologyBiochemistryNutrition DisordersSprue TropicalParenteral nutritionBasic researchIntensive caremedicineClinical staffHomeostasisAmino AcidsIntensive care medicineBurnsFood ScienceZeitschrift fur Ernahrungswissenschaft
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