Search results for "Disposition"

showing 10 items of 832 documents

Rats bred for low intrinsic aerobic exercise capacity link obesity with brain inflammation and reduced structural plasticity of the hippocampus.

2021

Abstract BACKGROUND Increasing evidence shows obesity and poor metabolic health are associated with cognitive deficits, but the mechanistic connections have yet to be resolved. We studied rats selectively bred for low and high intrinsic aerobic capacity in order to test the association between low physical fitness, a genetic predisposition for obesity, and brain health. We hypothesized that low-capacity runner (LCR) rats with concurrently greater levels of adiposity would have increased hippocampal inflammation and reduced plasticity compared to the more physically fit high-capacity runner (HCR) rats. METHODS We examined markers for inflammation and brain plasticity in the hippocampi of LCR…

kognitioPhysical fitnessbiomarkkeritHippocampal formationHippocampusBehavioral Neuroscience0302 clinical medicineHippocampus (mythology)aineenvaihduntaAdiposity2. Zero hunger0303 health sciencesExercise TolerancetulehdusNeurogenesisylipainoneurogenesisfyysinen kuntoEncephalitisgeneettiset tekijätmedicine.symptomaivotkognitiiviset taidotmedicine.medical_specialtyneuroplasticityImmunologyInflammationperinnöllinen alttius03 medical and health sciencesInternal medicinePhysical Conditioning AnimalNeuroplasticitymedicineGenetic predispositionAerobic exerciseAnimalshippokampusObesityneuroplastisuus030304 developmental biologyEndocrine and Autonomic Systemsbusiness.industrysytokiinitsynaptic proteinscytokinesRatshermosolutEndocrinologylihavuusproteiinitbusinesshuman activities030217 neurology & neurosurgeryBrain, behavior, and immunity
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A classical phenotype of Anderson-Fabry disease in a female patient with intronic mutations of the GLA gene: a case report

2012

Abstract Background Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids in the lysosomes with subsequent cellular and microvascular dysfunction. The incidence of disease is estimated at 1:40,000 in the general population, although neonatal screening initiatives have found an unexpectedly high prevalence of genetic alterations, up to 1:3,100, in newborns in Italy, and have identified a surprisingly high frequency of newborn males with genetic alterations (about 1:1,500) in Taiwan. Case presentation We des…

lcsh:Diseases of the circulatory (Cardiovascular) systemPathologyα-galactosidase AAnderson-Fabry mutationBiopsyDNA Mutational AnalysisCase Reportmedicine.disease_causeGlobotriaosylceramide0302 clinical medicineSettore BIO/13 - Biologia ApplicataPromoter Regions Genetic0303 health sciencesMutationeducation.field_of_studymedicine.diagnostic_testbiologyMetabolic disorderMagnetic Resonance Imaging3. Good healthPhenotypeCardiovascular DiseasesDisease ProgressionFemaleKidney DiseasesRenal biopsyCardiology and Cardiovascular MedicineAdultmedicine.medical_specialtyPopulation03 medical and health sciencesPredictive Value of TestsBiopsymedicineHumansHigh resolution meltingGenetic Predisposition to Diseaseeducation030304 developmental biologyFabry diseaseAlpha-galactosidasebusiness.industrymedicine.diseaseFabry diseaseIntronslcsh:RC666-701alpha-GalactosidaseMutationGLAbiology.proteinbusiness030217 neurology & neurosurgeryKidney disease
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Mood, Burnout, and Dispositional Optimism in Kayak Polo Players During Their Competitive Stage.

2021

© 2021. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Accepted Manuscript version of a Published Work that appeared in final form in Frontiers in Psychology. To access the final edited and published work see 10.3389/fpsyg.2021.667603 The main objective of performance sport is to obtain achievements at the highest level through the adequate development of the athlete. The scientific literature demonstrates the fundamental role played by the inclusion of certain psychological variables in the training plan. This study examined the psychological profile of kayak polo players through the variables of burnou…

media_common.quotation_subjectDispositional optimismBurnoutpsychological variablesLOT-R03 medical and health sciences0302 clinical medicineOptimismsport performanceTraining planPsychology0501 psychology and cognitive sciencesPOMSSenioritykayakEmotional exhaustionGeneral Psychologymedia_commonOriginal ResearchtrainingbiologyAthletes05 social sciences030229 sport scienceskayak polobiology.organism_classificationBF1-990050106 general psychology & cognitive sciencesMood:1 - Filosofía y psicología::159.9 - Psicología [CDU]IBD-RPsychologyClinical psychologyFrontiers in psychology
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Influence of Resilience and Optimism on Distress and Intention to Self-Isolate: Contrasting Lower and Higher COVID-19 Illness Risk Samples From an Ex…

2021

The study investigated the influence of resilience and dispositional optimism on, first, emotional distress and, second, the intention to self-isolate, experienced by people with a lower and higher illness risk, during the lockdown imposed in Spain during the first COVID-19 wave. These effects were investigated against the background of the Health Belief Model (HBM). A convenience sample of N = 325 participants completed an online survey including an ad-hoc questionnaire measuring the HBM core factors: Perceived health threat (susceptibility and severity of getting infected), and perceived quarantine benefits and costs. Self-efficacy and perceived social pressure were also measured. Based o…

media_common.quotation_subjectLower riskSalud mental03 medical and health sciences0302 clinical medicineOptimismEpidemiamedicineHealth belief modelhealth belief modelPsychology030212 general & internal medicineGeneral Psychologyresilience (psychological)Original Researchmedia_commonintention to self-isolateResiliencia psicológicadispositional optimismCOVID-19distressLonelinessBoredomBF1-990DistressDistrés psicológicoPsychological resiliencemedicine.symptomPsychologyPsychosocial030217 neurology & neurosurgeryillness riskClinical psychologyFrontiers in Psychology
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The mediating role of optimism in the relations between sense of coherence, subjective and psychological well-being among late adolescents

2015

Abstract The purpose of this study was to examine whether optimism is a mediator between sense of coherence, subjective well-being and psychological well-being among late adolescents. Two hundred and eleven participants completed the Sense of Coherence Scale, the Life Orientation Test-Revised, the Satisfaction With Life Scale, the Positive and Negative Affect Schedule, and the Psychological Well-Being Scale. Results of path analysis revealed both direct and indirect effects of sense of coherence on subjective and psychological well-being measures, suggesting that optimism served as a partial mediator. The mediating role of optimism may be more fully understood within the framework of the se…

media_common.quotation_subjectOptimism; Sense of coherence; Subjective and psychological well-being; Late adolescentsDispositional optimismDevelopmental psychologyOptimismPositive and Negative Affect SchedulePsychological well-beingLife orientationPath analysis (statistics)PsychologySocial psychologyGeneral PsychologySense of coherencemedia_commonPersonality and Individual Differences
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Finnish Students' School Engagement Profiles in the Light of PISA 2003

2008

The aim of this study is to examine Finnish students' school engagement profiles in the light of the data collected in the PISA (Programme for International Student Assessment) in 2003. Even though Finnish students' cognitive achievement has proved excellent in various international assessments, their school engagement has not been flattering. The article first defines the concept of school engagement and discusses some previous findings on students' attitudes and socio‐emotional disposition towards school life. Next, on the basis of students' responses to the PISA 2003 survey questionnaire, students are grouped and the groups profiled by cluster analysis into six distinct clusters in terms…

media_common.quotation_subjectSelf-conceptCognitionDispositioncomputer.software_genrePeer acceptanceEducationReading (process)PerceptionEducational assessmentPedagogyMathematics educationSchool engagementPsychologycomputermedia_commonScandinavian Journal of Educational Research
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"optimism Is a Strategy for Making a Better Future": A Systematic Review on the Associations of Dispositional Optimism with Health-Related Quality of…

2022

Abstract. Cancer is a deadly disease that can lead to psychological suffering and decreased quality of life (QoL). Personality has been proven to have an effect on QoL and, in particular, Dispositional Optimism (DO) has been studied in relation to overcoming health crisis. The aim of this systematic review is to deepen the state of art of the relationship between QoL and DO in cancer patients. PubMed and Embase databases were systematically searched. Fifteen studies were included with a total of 5,249 cancer patients. All of the studies consider the relationship between DO and QoL, some studies analyze the correlation between the two variables and found a positive association. The majority…

media_common.quotation_subjectdispositional optimismCancerDispositional optimismDiseasemedicine.diseasehumanitiescancer care03 medical and health sciences0302 clinical medicineOptimismArts and Humanities (miscellaneous)Quality of lifequality of life030220 oncology & carcinogenesismedicinePersonality030212 general & internal medicinePsychologycancer patientsGeneral Psychologymedia_commonClinical psychology
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The Moderating Role of Intellectual Humility in the Adoption of ICT: A Study Across Life-Span

2018

Literature has shown age-related differences in the adoption process. In this way, it is very important to encourage the adoption of ICT by the elderly, in order to maintain their independence in daily life. However, some specific cognitive variables were not considered in theoretical models until a decade ago. One of the emerging fields in this area is the science of learnable intelligence, which investigates the role of thinking dispositions. The variable which we have focused on is intellectual humility. For this propose, a sample of 306 participants from 18 to 87 years was selected. Age was selected as a predictor variable. Intellectual humility was tested as a moderator between ageing …

media_common.quotation_subjectlcsh:BF1-990050109 social psychologySample (statistics)Humilitythinking dispositions050105 experimental psychologyId ego and super-egoPsychology0501 psychology and cognitive sciencesGeneral Psychologymedia_commonOriginal Researchbusiness.industryintellectual humility05 social sciencesModerationIndependencecognitive variablesPersonal developmentlcsh:PsychologyageInformation and Communications TechnologyICTIntellectbusinessPsychologySocial psychologyFrontiers in Psychology
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Electrocardiographic Indices of Left Ventricular Hypertrophy and Repolarization Phase Share the Same Genetic Influences: A Twin Study

2009

Background: Both left ventricular hypertrophy (LVH) and repolarization phase (RP) are known to be attributable to genetic influences, but less is known whether they share same genetic influences. The aim of this study was to investigate to what extent individual differences in electrocardiographic (ECG) LVH and RP are explained by genetic and environmental influences and whether these influences are shared between these two traits. Methods: Resting ECG recordings were obtained from 186 monozygotic and 203 dizygotic female twin individuals, aged 63 to 76 years. Latent factors, called LVH and RP, were formed to condense the information obtained from LVH indices (Cornell voltage and Cornell pr…

medicine.medical_specialty030204 cardiovascular system & hematologyLeft ventricular hypertrophyGenetic correlationCorrelationElectrocardiography03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineGenetic modelingHumansRepolarizationMedicineGenetic Predisposition to Diseasecardiovascular diseases030212 general & internal medicineAgedbusiness.industryOriginal ArticlesGeneral MedicineMiddle AgedHeritabilitymedicine.diseaseTwin studyEndocrinologyCardiologyFemaleHypertrophy Left VentricularCardiology and Cardiovascular MedicinebusinessAnnals of Noninvasive Electrocardiology
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Genetic influences on resting electrocardiographic variables in older women: a twin study.

2009

Background: Previous studies in young and middle-aged men and women have shown that resting electrocardiographic (ECG) variables are influenced by genetic factors. However, the extent to which resting ECG variables are influenced by genetic factors in older women is unknown. Thus, the aim of this study was to estimate the relative contribution of genetic and environmental influences to individual differences in resting ECG variables among older female twins without overt cardiac diseases. Methods: Resting ECG recordings were obtained from 186 monozygotic and 203 dizygotic twin individuals, aged 63–76 years. Quantitative genetic modeling was used to decompose the phenotypic variance in each …

medicine.medical_specialtyAgingDizygotic twinRestTwins030204 cardiovascular system & hematologyQT intervalCohort Studies03 medical and health sciencesQRS complexElectrocardiography0302 clinical medicineHeart RateReference ValuesPhysiology (medical)Internal medicineHeart ratemedicineConfidence IntervalsTwins DizygoticHumansGenetic Predisposition to Diseasecardiovascular diseasesFinland030304 developmental biologyAged0303 health sciencesmedicine.diagnostic_testbusiness.industryGeneral MedicineTwins MonozygoticOriginal ArticlesHeritabilityMiddle AgedTwin studyConfidence intervalEndocrinologyCardiologyFemaleCardiology and Cardiovascular MedicinebusinessElectrocardiographyAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
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