Search results for "Dissociation"

Cognitive Processing dissociation by mental effort manipulation in long demanding tasks

2020

AbstractIndividuals uses cognitive resources to modulate performance in demanding tasks and a non-invasive and reliable way of measuring mental effort is pupillometry. This study aimed to test the mental effort related to different processing systems in long tasks with controlled and automatic demands. We conducted two experiments with healthy subjects: in Experiment 1 (n=15), using a metronome to ensure control on task pace, participants performed a serial number generation task (Counting; little to no effort tasks), a random number generation (RNG; effortful tasks), and no task (Unfilled interval; no effort at all). In experiment 2, (n=15) participants performed counting tasks with or wit…

The effect of explicit knowledge on sequence learning: A graded account

2004

In this paper, we study the effect of conscious knowledge on implicit sequence learning. To do so, in three sequence learning experiments, we manipulated (1) the extent to which instructions were intentional vs. incidental - intentional participants were informed of the existence of sequential regularities, and (2) the amount of explicit knowledge given to participants about the stimulus material. Results indicated that explicit knowledge improves sequence learning, as indexed by an increase in reaction times when the training sequence is unexpectedly replaced by another one. To enable us to differentiate between implicit and explicit learning, we applied the process dissociation procedure …

2019

Objective. Several studies have reported that people with Parkinson’s disease (PD) perform poorly on tests of ‘Theory of Mind’ (ToM), suggesting impairment in the ability to understand and infer other people’s thoughts and feelings. However, few studies have sought to separate the processes involved in social reasoning from those involved in managing the inhibitory demands on these tests. In this study, we investigated the contribution of inhibition to ToM performance in PD. Methods. 18 PD patients and 22 age-matched healthy controls performed a ToM test that separates the ability to infer someone else’s perspective from the ability to inhibit one’s own. Participants also completed a batter…

Avoidant coping style and verbal-cardiovascular response dissociation

1996

Abstract This study explored the relationship between an avoidant coping style and three responses during three experimental periods (i.e., speech preparation, speech delivery, and recovery). One response was cardiovascular reactivity, the two other responses were subjective in nature: self-reports of anxiety and self-estimations of blood pressure. Subjects were 20 male and 20 female students who scored either in the upper third (i.e., high-avoiders) or lower third (i.e., low-avoiders) on cognitive avoidance (Krohne, 1989). When compared to subjects scoring low on avoidance, those high on avoidance showed greater systolic blood pressure (SBP) reactivity and evidenced verbal-autonomic respon…

Letter Position Coding Across Modalities: The Case of Braille Readers

2012

BackgroundThe question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words.MethodologyHere we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille…

Rupture Force of Single Small Drug Molecule Binding a Split Aptamer

2012

Aptamers are specific oligonucleotides (DNA or RNA) which bind small inorganic or organic molecules, large proteins or cells. In particular, the high affinity of aptamers is expected to lead to a new class of therapeutic reagents. Thus the detection and characterization of binding strength of small molecules is important for drug and medical research. Atomic force spectroscopy (AFS) with a force resolution in the piconewton range is a valuable tool for studying interactions on a single molecular level. The detection of very small target molecules less than 500 Dalton is characterized by only a few hydrogen interactions between the aptamer and the target molecules. Thus tiny rupture forces w…

Thermometric study of the dissociation equilibria of the maleinimidodioxime

1982

The values of the dissociation constants of the maleinimidodioxime are potentiometrically determined at various ionic strengths, and extrapolated to zero ionic strength (pK1T=10.41;pk2T=11.60). From these values and from the thermometric titration curves the enthalpies of neutralization (ΔHN1=−21.76,ΔHN2=−23.77 kJ/mol) and the thermodynamic parameters of dissociation of this substance at 25.0 °C are determined (ΔG1θ=59.41,ΔG2θ=66.23,ΔH1θ=34.06,ΔH2θ=32.05 kJ/mol;ΔS1θ=−85.06,ΔS2θ=−114.64 J/(K mol)).

Leitfahigkeitsmessungen an Polystyrylnatrium in Dimethoxiäthan (DME) und Tetrahydrofuran (THF)

1971

An Polystyrylnatrium werden in zwei polaren organischen Losungsmitteln Leitfahigkeitsmessungen uber einen groseren Temperaturbereich ausgefuhrt. Aus der Temperaturabhangigkeit der Dissoziationskonstante ergibt sich, das die undissoziierte Verbindung in zwei Formen, dem Kontaktionenpaar (I) und dem solvatgetrennten Ionenpaar (II), vorkommt. Enthalpie- und Entropiedifferenz beim ubergang von I nach II, sowie die entsprechenden thermodynamischen Parameter der Dissoziation von II werden ermittelt. Der effektive Ladungsabstand im solvatgetrennten Ionenpaar betragt etwa 7 A. Conductivity measurements were carried out with polystyryl sodium in two polar solvents within a large temperature range. T…

The Dissociation Constant of Pyruvic Acid: Determination by Spectrophotometric Measurements

1991

Aqueous solutions of sodium pyruvate/hydrochloric acid mixtures were studied with regard to changes in the intensity of optical absorption at 317 nm wavelength, caused by varying pH and temperature. The data were evaluated to determine the pyruvic acid apparent dissociation constant at infinite dilution. Its temperature dependence followed the relation ln Kod = −(0.55 ± 0.47) − (1538 ± 135)/T or, if previous results of Pedersen at two temperatures are included, In Kod = −(0.97 ± 0.35) − (1418 ± 102)T. The effective absorption coefficient for pyruvic acid and its anion differ because the former species is largely hydrated, whereas the latter is not. The known hydration constant and its tempe…

1984