Search results for "Distre"

showing 10 items of 609 documents

SARS CoV2 infection _The longevity study perspectives

2021

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MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
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Free-to-play: About addicted Whales, at risk Dolphins and healthy Minnows. Monetarization design and Internet Gaming Disorder

2015

Abstract Introduction Video games are not only changing due to technical innovation, but also because of new game design and monetization approaches. Moreover, elite gamer groups with financial in-game-investments co-finance all users of free-to-play-games. Besides questions on youth protection, the growing popularity of free-to-play games has fostered discussions on supposed associations to Internet Gaming Disorder (IGD). Method Children and adolescents using free-to-play browser games were examined in a German school-based representative study (N = 3967; age range 12 to 18). Based on a clinical self-report AICA-S (Wolfling et al., 2011), students were categorized into non-problematic, ris…

MaleCoping (psychology)AdolescentChild BehaviorMedicine (miscellaneous)Dysfunctional familyToxicologyDevelopmental psychology03 medical and health sciences0302 clinical medicineGame designGermanySurveys and QuestionnairesAdaptation PsychologicalHumansChildInternetbusiness.industryAge FactorsPopularityPlay and Playthings030227 psychiatryBehavior AddictivePsychiatry and Mental healthClinical PsychologyDistressVideo GamesAdolescent BehaviorFemaleThe InternetPsychologyFree to playbusinessStress Psychological030217 neurology & neurosurgeryPsychopathologyAddictive Behaviors
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Psychological experience of patients 3 months after a stay in the intensive care unit: A descriptive and qualitative study.

2015

Abstract Purpose The purpose was to describe psychological experiences of patients 3 months after a stay in the intensive care unit (ICU) using qualitative methods. Methods Twenty patients underwent clinical interview lasting 1 hour and completed the Impact of Event Scale—Revised and Hospital Anxiety and Depression questionnaires. All interviews were recorded and coded using thematic analysis. Results All patients (100%) reported that they could not remember their ICU stay; half reported confused memories (50%) or disorientation (50%). Negatives memories were also reported (20%-45%), namely, pain, distress, sleep difficulties, noise, fear, feeling of abandonment; 20% reported positive memor…

MaleCoping (psychology)medicine.medical_specialtymedia_common.quotation_subjectFamily supportEmotions[SHS.PSY]Humanities and Social Sciences/PsychologyAnxietyCritical Care and Intensive Care Medicinelaw.inventionStress Disorders Post-Traumatic03 medical and health sciences0302 clinical medicineOptimismlawSurveys and QuestionnairesAdaptation PsychologicalInterview PsychologicalmedicineHumans030212 general & internal medicineProspective StudiesPsychiatryComputingMilieux_MISCELLANEOUSQualitative Researchmedia_commonAgedbusiness.industryDepression030208 emergency & critical care medicineFearLength of StayMiddle AgedIntensive care unitPatient Discharge3. Good healthDistressIntensive Care UnitsMemory Short-TermFeelingAnxietyFemaleThematic analysismedicine.symptombusinessJournal of critical care
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A Cross-Country Examination on the Fear of COVID-19 and the Sense of Loneliness during the First Wave of COVID-19 Outbreak

2021

The aim of the current study is to examine gender, age. and cross-country differences in fear of COVID-19 and sense of loneliness during the lockdown, by comparing people from those countries with a high rate of infections and deaths (e.g., Spain and Italy) and from countries with a mild spread of infection (e.g., Croatia, Serbia, Slovakia, Slovenia, and Bosnia and Herzegovina). A total of 3876 participants (63% female) completed an online survey on “Everyday life practices in COVID-19 time” in April 2020, including measures of fear of COVID-19 and loneliness. Males and females of all age groups in countries suffering from the powerful impact of the COVID-19 pandemic reported greater fear o…

MaleCross-country Fear of COVID-19 Loneliness Psychosocial distress COVID-19Health Toxicology and MutagenesisSloveniapandemijecoronaviruslcsh:MedicineDisease Outbreaksrestrictions0302 clinical medicineEconomic costPandemicstrah030212 general & internal medicineEveryday lifeukrepipublic healthLonelinessFearItalypsihosocialne stiskefearFemalemedicine.symptomPsychologySerbiaisolationmedicine.medical_specialtySlovakiaCoronavirus disease 2019 (COVID-19)Croatiafear of COVID-19Article03 medical and health sciencesmedicinelonelinessHumansPandemicsAgedBosnia and Herzegovinaudc:616-036.21:614:616.89-008.441osamljenostSARS-CoV-2koronavirusPublic healthpandemicjavno zdravjelcsh:RPublic Health Environmental and Occupational HealthOutbreakCOVID-19psychosocial distressMental healthSpainCommunicable Disease Controlcross-country030217 neurology & neurosurgeryDemographyizolacijaInternational Journal of Environmental Research and Public Health
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Course of social support and associations with distress after partial laryngectomy

2021

PURPOSE Social support has been shown to be positively associated with quality of life and adjustment after a cancer diagnosis. The present study investigates the course of social support up to one year after partial laryngectomy and its association with distress. DESIGN Longitudinal questionnaire study. SAMPLE A total of 428 patients after partial laryngectomy (mean age: 64, SD = 11, 91% male). METHODS Patients completed questionnaires before treatment (t1), one week after a partial laryngectomy (t2), 3 months (t3), and one year (t4) thereafter. Social support was evaluated at t2, t3, and t4 using a brief version of the Social Support Questionnaire. Distress was measured at t2, t3, and t4 …

MaleDescriptive statisticsbusiness.industrySocial SupportLaryngectomyMiddle AgedPsychiatry and Mental healthDistressSocial supportOncologyQuality of lifeSurveys and QuestionnairesQuality of LifeHumansMedicineFemaleLongitudinal StudiesProspective cohort studybusinessPsychosocialApplied PsychologyPartial laryngectomyClinical psychologyQuestionnaire studyJournal of Psychosocial Oncology
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The role of mind theory in patients affected by neurodegenerative disorders and impact on caregiver burden

2020

Abstract Background Theory of Mind (ToM) is defined as the ability to understand mental and emotional state. This ability is assessed also in neurodegenerative disease. Few studies have investigated the impact that social cognition of patients could have on caregiver burden. The aim of this study was to investigate a possible correlation in level of social cognition impairment between patients with different neurodegenerative disorders and their caregivers with possible impact on caregivers burden. Methods we enrolled 48 patients with dementia divided in different groups: Fronto-Temporal Dementia (FTD), Alzheimer Disease (AD), and Mild Cognitive Impairment (MCI) and also the three groups of…

MaleEmotionsTheory of MindDiseaseFronto-temporal dementia03 medical and health sciences0302 clinical medicineSocial cognitionAlzheimer DiseasePhysiology (medical)Theory of mindmental disordersActivities of Daily Livingmedicine80 and overDementiaHumansIn patientCognitive DysfunctionAlzheimer disease; Caregiver; Dementia; Fronto-temporal dementia; Mild cognitive impairment; Theory of mind; Activities of Daily Living; Aged; Aged 80 and over; Alzheimer Disease; Caregivers; Cognitive Dysfunction; Emotions; Female; Frontotemporal Dementia; Humans; Male; Middle Aged; Neurodegenerative Diseases; Theory of MindAgedAged 80 and overbusiness.industryMild cognitive impairmentNeurodegenerative DiseasesGeneral MedicineCaregiver burdenMiddle Agedmedicine.diseaseCaregiverDistressNeurologyCaregivers030220 oncology & carcinogenesisFrontotemporal DementiaSurgeryDementiaFemaleNeurology (clinical)Alzheimer's diseasebusiness030217 neurology & neurosurgeryClinical psychology
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The Mediating Role of Psychological Distress in Excessive Gambling among Young People: A Four-Country Study

2021

Background and aims: Loneliness and a low sense of mastery are associated with excessive gambling, but the underlying processes of these relationships remain unstudied. Because psychological distress can increase vulnerability to excessive gambling, we investigated its mediating role in these relationships among young people. To meet the need for cross-country research, we also observed how these relationships occur in four countries with different cultures. Design, setting, and participants: Demographically balanced cross-sectional survey data were collected from 15–25-year-olds in Finland (n = 1200

MaleHealth Toxicology and MutagenesisVulnerability030508 substance abuse0302 clinical medicinenuoretpsychological distressadolescentsYoung adultFinlandRLonelinessapplied_psychology3142 Public health care science environmental and occupational healthPREVALENCEADDICTIONyksinäisyysScale (social sciences)5141 SociologyGAMBLERSMedicineFemaleHEALTHmedicine.symptom0305 other medical sciencePsychologyClinical psychologyAdultyoung adultsAdolescent515 PsychologyArticleYoung Adult03 medical and health sciencessense of masteryRepublic of KorearahapelitlonelinessmedicineHumansVALIDITYAssociation (psychology)nuoret aikuisethenkinen pahoinvointiPublic Health Environmental and Occupational HealthelämänhallintaPATHWAYSPsychological distressongelmapelaaminen030227 psychiatryCross-Sectional StudiesSpainGamblingexcessive gamblingSurvey data collectionSCREENGeneral Health QuestionnaireInternational Journal of Environmental Research and Public Health
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Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study

2019

Editor's Perspective What We Already Know about This Topic Hospital mortality in acute respiratory distress syndrome is approximately 40%, but mortality and trajectory in "mild" acute respiratory distress syndrome (classified only since 2012) are unknown, and many cases are not detected What This Article Tells Us That Is New Approximately 80% of cases of mild acute respiratory distress syndrome persist or worsen in the first week; in all cases, the mortality is substantial (30%) and is higher (37%) in those in whom the acute respiratory distress syndrome progresses Background: Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered …

MaleInternationalityRespiratory Distress Syndrome Adultadult respiratory distress syndromeMiddle AgedSeverity of Illness IndexPatient Outcome AssessmentProspective StudieAnesthesiology and Pain MedicineSettore MED/41 - ANESTESIOLOGIAARDSFemaleHospital MortalityAcute Respiratory Distress SyndromeHuman
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Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol…

2017

Background Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hemodynamics, and the effects on PPCs are uncertain. We hypothesized that intraoperative mechanical ventilation using high PEEP with periodic recruitment maneuvers, as compared with low PEEP without recruitment maneuvers, prevents PPCs in obese patients. Methods/design The PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients (PROBESE) study is a multice…

MaleLung DiseasesTime Factors[SDV]Life Sciences [q-bio]Respiratory Medicine and Allergymedicine.medical_treatmentRESPIRATORY-DISTRESS-SYNDROMEMedicine (miscellaneous)HemodynamicsMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuver; Medicine (miscellaneous); Pharmacology (medical)LAPAROSCOPIC BARIATRIC SURGERYLung DiseaseBody Mass Indexlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationClinical ProtocolsRandomized controlled trialRisk Factors030202 anesthesiologylawMedicine and Health SciencesClinical endpointAnesthesiaPharmacology (medical)Respiratory function030212 general & internal medicineLungLungmedicin och allergi2. Zero hungerlcsh:R5-920ddc:617Positive end-expiratory pressurerespiratory systemOperative3. Good healthTreatment OutcomeRecruitment maneuverTIDAL VOLUMESResearch DesignMechanical ventilation Positive end-expiratory pressure Recruitment maneuver Obesity Postoperative pulmonary complicationSurgical Procedures OperativeAnesthesiaBreathingFemaleErratumlcsh:Medicine (General)ALVEOLAR RECRUITMENT MANEUVERHumancirculatory and respiratory physiologymedicine.medical_specialtyTime FactorMechanical ventilation ; Obesity ; Positive end-expiratory pressure ; Postoperative pulmonary complication ; Recruitment maneuverAnesthesia GeneralLung injuryMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuver; Body Mass Index; Clinical Protocols; Female; Humans; Intraoperative Care; Lung; Lung Diseases; Male; Obesity; Positive-Pressure Respiration; Protective Factors; Research Design; Risk Factors; Time Factors; Treatment Outcome; Anesthesia General; Surgical Procedures Operative; Medicine (miscellaneous); Pharmacology (medical)NOGENERAL-ANESTHESIADRIVING PRESSURE03 medical and health sciencesmedicineHumansddc:610ObesityClinical ProtocolGeneralProtective FactorPositive end-expiratory pressurePOSTOPERATIVE PULMONARY COMPLICATIONSMechanical ventilationSurgical ProceduresIntraoperative CareINTERNATIONAL CONSENSUSbusiness.industryRisk FactorProtective FactorsSurgeryMechanical ventilation; Obesity; Positive end-expiratory pressure; Postoperative pulmonary complication; Recruitment maneuverrespiratory tract diseasesbusinessPostoperative pulmonary complicationLUNG INJURY
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Screening for distress in routine oncological care-a survey in 520 melanoma patients.

2012

Introduction Despite the increasing incidence of melanoma little is known about patients' emotional distress associated with this disease. Supplemented by the problem list (PL), the distress thermometer (DT) is a recommended screening instrument to measure psychosocial distress in cancer patients. Our objective was to explore the acceptance and the feasibility of the DT and PL as a concise screening tool in an ambulatory setting for routine care and to elucidate determinants of distress in melanoma patients with regard to sociodemographic and clinical variables. Methods Consecutive melanoma outpatients were asked to complete the DT with the PL prior to their scheduled consultation. Demograp…

MaleMelanomasPediatricsSkin NeoplasmsNon-Clinical MedicineEpidemiologyEmotionsProblem listlcsh:MedicineDiseaseSocial and Behavioral SciencesQuality of lifeRisk FactorsSurveys and QuestionnairesOutpatientsMass ScreeningPsychologyYoung adultlcsh:ScienceMelanomaSkin TumorsAged 80 and overMultidisciplinaryIncidence (epidemiology)Malignant MelanomaMiddle AgedDistressClinical PsychologyMental HealthOncologyMedicineFemalePsychosocialResearch ArticleTest EvaluationAdultmedicine.medical_specialtyAdolescentSocial PsychologyPsychological StressMalignant Skin NeoplasmsDermatologyYoung AdultDiagnostic MedicinemedicineHumansPsychiatryMass screeningAgedBehaviorHealth Care Policybusiness.industrylcsh:RCancers and NeoplasmsSurvey MethodsHealth Care SurveysQuality of Lifelcsh:QbusinessStress PsychologicalPLoS ONE
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