Search results for "District"

Place-based innovation in industrial districts: the long-term evolution of the iMID effect in Spain (1991–2014)

2019

ABSTRACTThe innovation-Marshallian industrial district (iMID) effect defines the existence of dynamic efficiency in the Marshallian industrial district (MID) in the form of a positive innovative di...

Innovative culture in district innovation systems of European ceramics SMEs

2017

We need to understand the dynamics of current local production systems in the form of industrial districts and, particularly, how culture and innovation are interlinked. In this paper, we argue that the district innovation system approach, which covers the innovation systems and industrial district literatures, provides a set of ideas useful for understanding the role of culture in innovation in industrial districts. We study the role of innovation culture in two of the most important European ceramics industrial districts in Italy and Spain. Specifically, we analyse how, within a given district system, the innovation culture, networks and social structure, and their inter-relations, influe…

In Vivo Reprogramming for Brain and Spinal Cord Repair.

2015

AbstractCell reprogramming technologies have enabled the generation of various specific cell types including neurons from readily accessible patient cells, such as skin fibroblasts, providing an intriguing novel cell source for autologous cell transplantation. However, cell transplantation faces several difficult hurdles such as cell production and purification, long-term survival, and functional integration after transplantation. Recently,in vivoreprogramming, which makes use of endogenous cells for regeneration purpose, emerged as a new approach to circumvent cell transplantation. There has been evidence forin vivoreprogramming in the mouse pancreas, heart, and brain and spinal cord with …

Walmeermahzitajmuischs Protokollgrahmata

1850

Nationwide analysis on the impact of socioeconomic land use factors and incidence of urothelial carcinoma

2017

Incidence rates for urothelial carcinoma (UC) have been reported to differ between countries within the European Union (EU). Besides occupational exposure to chemicals, other substances such as tobacco and nitrite in groundwater have been identified as risk factors for UC. We investigated if regional differences in UC incidence rates are associated with agricultural, industrial and residential land use.Newly diagnosed cases of UC between 2003 and 2010 were included. Information within 364 administrative districts of Germany from 2004 for land use factors were obtained and calculated as a proportion of the total area of the respective administrative district and as a smoothed proportion. Fur…

Impact of Ebola outbreak on reproductive health services in a rural district of Sierra Leone: a prospective observational study

2019

ObjectivesTo assess the trends concerning utilisation of maternal and child health (MCH) services before, during and after the Ebola outbreak, quantifying the contribution of a reorganised referral system (RS).DesignA prospective observational study of MCH services.SettingPujehun district in Sierra Leone, 77 community health facilities and 1 hospital from 2012 to 2017.Main outcome measuresMCH utililization was evaluated by assessing: (1) institutional deliveries, Cesarean-sections, paediatric and maternity admissions and deaths, and major direct obstetric complications (MDOCs), at hospital level; (2) antenatal care (ANC) 1 and 4, institutional delivery and family planning, at community leve…

An agent-based model to support the preliminary design and operation of heating and power grids with cogeneration units and photovoltaic panels in de…

2022

The increase in the energy demands of residential neighborhoods constitutes a huge challenge to be faced. A viable option lies in the insertion of both renewable energy production systems and cogeneration units within urban territories. On-site production allows for the satisfaction of the heating and electrical demands of end-users and favors the distribution of produced energy within the neighborhood, especially under the regulatory framework of energy communities. This paper proposes a tool to model heating and electricity networks integrated with cogeneration units and PV panels installed in urban areas. The tool accounts for the following possibilities: (i) energy flow management and p…

Branch-Price-and-Cut for the Soft-Clustered Capacitated Arc-Routing Problem

2021

The soft-clustered capacitated arc-routing problem (SoftCluCARP) is a variant of the classical capacitated arc-routing problem. The only additional constraint is that the set of required edges, that is, the streets to be serviced, is partitioned into clusters, and feasible routes must respect the soft-cluster constraint, that is, all required edges of the same cluster must be served by the same vehicle. In this article, we design an effective branch-price-and-cut algorithm for the exact solution of the SoftCluCARP. Its new components are a metaheuristic and branch-and-cut-based solvers for the solution of the column-generation subproblem, which is a profitable rural clustered postman tour …

The first colonization of Ibiza and Formentera (Balearic Islands, Spain): Some more islands out of the stream?

1995

Abstract The Balearic Islands, off the east coast of Spain, have provided a focus of interest in investigations of the earliest colonization of the Mediterranean islands, because of the relatively late date of their oldest sites. Mallorca was visited in the fifth millennium BC and inhabited by the third, and Menorca was colonized during the closing centuries of the third millennium; this therefore makes Ibiza and Formentera special cases of isolation, since they were evidently not occupied until about 2000 BC and moreover were essentially deserted between roughly the thirteenth and seventh centuries BC. The paper presents all the currently available data relevant to this question, particula…

The territories of tourism: a reflection about the experience of the Tourist Districts (Local Tourism Systems) in Sicily

2013

The tourist district is an important tool for territorial governance of regional tourism. The district is a type of Local System which is characterized by its multidimensionality, as well as the spatial contiguity of traders who belong to it. The territory is a space transformed by social interactions and relations of production: it is therefore the indispensable reference for measuring the impact of tourism. A bottom up approach in the process of identification of the districts is therefore vital. A Balance Score Card-approach is desirable to correctly manage this process. This study is a preliminary analysis derived from direct experience of the Sicilian tourist districts, recently formed…