Search results for "Diuresis"
showing 8 items of 28 documents
Der Einflu� partieller Adrenalektomien auf Wasserdiurese und endogene Kreatinin-Clearance bei einseitig nephrektomierten Ratten
1959
Die Ausbildung verschieden starker Stauungs�deme bei der Ratte und ihre Beseitigung durch Chlorothiazid
1960
1. After tying of the jugular veins a congestion edema of differing intensity was produced by oral loading of rats with varying amounts of saline. 2. Chlorothiazid (10 or 50 mg./kg. i.v.) given 24 hours after tying of the jugular veins increased the diuresis and sodium excretion to approximately the same values in edematous and normal animals. 3. The effect of chlorothiazid on renal excretion is not influenced by the severity of the edema and is not quantitatively related to reduction of edema.
Synthesis of recombinant atrial natriuretic peptide (rANP) using hybrid fusion protein-phage fr coat/ANP (CP/ANP).
1997
Abstract Baumanis, V., I. Jansone, A. Skangals, I. Mandrika and V. Berzins. Synthesis of recombinant atrial natriuretic peptide (rANP) using hybrid fusion protein-phage fr coat/ANP (CP/ANP). Peptides 18(8) 1229–1235, 1997.—Recombinant atrial natriuretic peptide (rANP) was expressed in and isolated from E. coli. rANP was purified using HPLC. Amino acid analysis, partial sequencing, and molecular mass were determined. Fused protein was used to rise polyclonal antibodies and to develop of immunoenzymatic assays of rANP and CP/ANP. Experiments were designed to study rANP effects on isolated rabbit aortic strips and to examine hypotensive, diuretic, and natriuretic activity, as well as renal cre…
Der Einfluss von Oxytocin auf Diurese und Salzausscheidung bei Ratte und Mensch
1956
Rationale and Design of the Efficacy of a Standardized Diuretic Protocol in Acute Heart Failure Study
2021
AIMS: Although acute heart failure (AHF) with volume overload is treated with loop diuretics, their dosing and type of administration are mainly based upon expert opinion. A recent position paper from the Heart Failure Association (HFA) proposed a step-wise pharmacologic diuretic strategy to increase the diuretic response and to achieve rapid decongestion. However, no study has evaluated this protocol prospectively. METHODS AND RESULTS: The Efficacy of a Standardized Diuretic Protocol in Acute Heart Failure (ENACT-HF) study is an international, multicentre, non-randomized, open-label, pragmatic study in AHF patients on chronic loop diuretic therapy, admitted to the hospital for intravenous …
Predictors of diuresis response to levosimendan administration in patients with acute heart failure
2021
Abstract Funding Acknowledgements Type of funding sources: None. Levosimendan, a calcium sensitizer and potassium channel-opener, is appreciated for its effects on systemic and pulmonary hemodynamic and for the relief of symptoms in acute heart failure (AHF). Positive effects of levosimendan on renal function have been also described. The aim of the present analysis was to assess the predictors of the diuresis response to levosimendan administration in high risk acute heart failure patients. Methods We analysed 34 consecutive patients admitted with high risk AHF to one centre and treated in intensive cardiac care unit. Levosimendan was administered on top of other treatment as a 24-hour in…
Influence of induced intrauterine diuresis on the upper urinary tract
1993
There are many possible etiologies of sonographically detected dilatation of the renal pelvis and the ureter during pregnancy. The observation that fetal ureteral dilatation occurs with congenital diabetes insipidus has led to the suspicion of at least a modifying influence resulting from intrauterine diuresis. To increase fetal diuresis experimentally, Wistar rats were treated with 100 mg chlorthalidon and 40 mg furosemide per kg bodyweight per day. The animal experiment was performed with four groups. Group I was treated during the entire course of pregnancy. Group II during the first half and Group III during the second half. Group C was the untreated control group. For morphometric inve…
Indomethacin treatment in amphotericin B induced nephrogenic diabetes insipidus.
1994
Nephrogenic diabetes insipidus (NDI) is a serious side effect of various drugs. Elevated renal prostaglandin E2 levels have been found in patients with lithium-induced NDI and have been implicated in the pathogenesis. We report the case of a patient who developed NDI following treatment with amphotericin B. Prostaglandin levels were elevated. Indomethacin had an antidiuretic effect and normalized prostaglandin levels.