Search results for "Document"

showing 10 items of 1535 documents

ULearn: Personalized Medical Learning on the Web for Patient Empowerment

2019

Abstract. Health literacy constitutes an important step towards patient empowerment and the Web is presently the biggest repository of medical information and, thus, the biggest medical resource to be used in the learning process. However, at present web medical information is mainly accessed through generic search engines that do not take into account the user specific needs and starting knowledge and so are not able to support learning activities tailored to the specific user requirements. This work presents “ULearn” a meta engine that supports access, understanding and learning on the Web in the medical domain based on specific user requirements and knowledge levels towards what we call …

020205 medical informaticsComputer scienceProcess (engineering)media_common.quotation_subjectDistance educationHealth literacy02 engineering and technologyInformation technologyPatient empowerment; search as learning; e-health; Health literacy; Health seeking behaviorUser requirements documentEducationWorld Wide WebDistance education03 medical and health sciences0302 clinical medicineResource (project management)0202 electrical engineering electronic engineering information engineeringInformation retrieval030212 general & internal medicineComputer softwareEmpowermentmedia_commonSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniSettore INF/01 - Informaticabusiness.industryCommunicationEducational technologyInformation technologyPatient empowerment search as learning e-health Health literacy Health seeking behavior.World Wide WebEducational technologyHealthbusiness
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Barriers and facilitators of older people's mHealth usage: a qualitative review of older people's views

2018

The aim of this qualitative evidence synthesis is to identify and assess existing\ud evidence on barriers to and facilitators of older people’s usage of mHealth. Existing\ud literature identified many factors that affect people’s experiences and perceptions of\ud mHealth, which are in turn influenced by their personal circumstances and biography.\ud The following themes were identified using the thematic synthesis approach: (a)\ud perception of usefulness, (b) user requirements, (c) self-efficacy, (d) sense of self and\ud control, (e) privacy and confidentiality, and (f) cost. MHealth devices and services are\ud complex interventions that have to be integrated into an older person’s life in…

020205 medical informaticsSocial Psychologymedia_common.quotation_subjectApplied psychologyPsychology of self02 engineering and technologyHMhyväksyminenAffect (psychology)User requirements documentPanacea (medicine)older people03 medical and health sciences0302 clinical medicinePromotion (rank)barriers and facilitatorsuser perspectivesRA0421qualitative evidence synthesisPerceptiontechnology acceptance0202 electrical engineering electronic engineering information engineeringConfidentiality030212 general & internal medicinemHealthmedia_commonCommunicationHuman-Computer InteractionmHealthteknologiakäyttäjäkokemusPsychologyikääntyneet
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Evaluation Framework for Analyzing the Applicability of Criteria Lists for the Selection of Requirements Management Tools Supporting Distributed Coll…

2016

Effective requirements management and enabling tools are critical for successfully developing and maintaining services and products. The identification and selection of an appropriate requirements management tool can be a costly, time-consuming, and error-prone undertaking especially in the context of software product line requirements management, requiring the tools to support both product and platform development activities that often involve geographically distributed, collaborating, and competing stakeholders. Criteria lists have been developed to facilitate the selection. This research (1) creates an evaluation framework to review the applicability of the lists for the selection of req…

0209 industrial biotechnologyRequirementBusiness requirementsComputer sciencesoftware managementSoftware requirements specification02 engineering and technologySoftware peer reviewApplication lifecycle management020901 industrial engineering & automationsoftware product lines0202 electrical engineering electronic engineering information engineeringSoftware requirementsformal verificationSoftware product lineRequirements analysisVision documentta113formal specificationsoftware toolsRequirements managementRequirements traceabilitybusiness.industrySoftware as a serviceSoftware developmenthallintajärjestelmät020207 software engineeringvaatimusmäärittelytdistributed collaborationMarket requirements documentRequirement prioritizationSoftware constructiontuotekehitysohjelmistoliiketoimintaSoftware engineeringbusinessSoftware project management2016 49th Hawaii International Conference on System Sciences (HICSS)
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Recentrifuge: Robust comparative analysis and contamination removal for metagenomics

2017

Metagenomic sequencing is becoming widespread in biomedical and environmental research, and the pace is increasing even more thanks to nanopore sequencing. With a rising number of samples and data per sample, the challenge of efficiently comparing results within a specimen and between specimens arises. Reagents, laboratory, and host related contaminants complicate such analysis. Contamination is particularly critical in low microbial biomass body sites and environments, where it can comprise most of a sample if not all. Recentrifuge implements a robust method for the removal of negative-control and crossover taxa from the rest of samples. With Recentrifuge, researchers can analyze results f…

0301 basic medicineBig DataSource codeComputer scienceBig dataNegative controlcomputer.software_genrelaw.invention0302 clinical medicineDocumentationlawlcsh:QH301-705.5media_commonEcologyMicrobiotaHigh-Throughput Nucleotide SequencingContaminationComputational Theory and MathematicsDNA ContaminationModeling and SimulationData miningAlgorithmsmedia_common.quotation_subjectComputational biologyBiology03 medical and health sciencesCellular and Molecular NeuroscienceGeneticsHumansMolecular BiologyEcology Evolution Behavior and SystematicsInternetWhole Genome Sequencingbusiness.industryPie chartComputational BiologyCorrectionSequence Analysis DNADNA Contamination030104 developmental biologylcsh:Biology (General)MetagenomicsMicrobial TaxonomyMetagenomeNanopore sequencingMetagenomicsbusinesscomputer030217 neurology & neurosurgerySoftwarePLoS computational biology
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Biallelic variants in LARS2 and KARS cause deafness and (ovario)leukodystrophy

2019

Supplemental Digital Content is available in the text.

0301 basic medicineLysine-tRNA LigaseMalePathologyMagnetic Resonance SpectroscopyMedizinmembrane proteins030204 cardiovascular system & hematologyMitochondrionDeafnessmedicine.disease_causeCompound heterozygosityCorrectionsLeukoencephalopathyMyelin0302 clinical medicineCytosolLeukoencephalopathies030212 general & internal medicineOvarian DiseasesTransfer RNA AminoacylationChildZebrafishMUTATIONExome sequencing10012MutationBrainMetabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6]General MedicineMiddle AgedDisorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]Magnetic Resonance ImagingMitochondriaProtein Transportendoplasmic reticulummedicine.anatomical_structureChild PreschoolTransfer RNAComputingMethodologies_DOCUMENTANDTEXTPROCESSING/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Biological AssayFemaleWRBRare cancers Radboud Institute for Health Sciences [Radboudumc 9]Adultcardiomyopathiesmedicine.medical_specialtyMitochondrial diseaseAminoacylationMuscle disorderBiologyArticleMEDIATES INSERTIONAmino Acyl-tRNA Synthetases03 medical and health sciencesSDG 3 - Good Health and Well-beingmedicineAnimalsPoint MutationHumansAmino Acid SequenceAlleleAllelesCOMPLEXGenetic heterogeneitybusiness.industryArsenite Transporting ATPasesLeukodystrophyGenetic Variation10090Original ArticlesZebrafish Proteinsbiology.organism_classificationDILATED CARDIOMYOPATHYmedicine.diseasezebrafishGENEMolecular biologyDisease Models Animal030104 developmental biologyMembrane protein[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics10084Neurology (clinical)Transfer RNA AminoacylationMEMBRANEbusinessSequence Alignment030217 neurology & neurosurgeryexomeNeurology
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CD19 Isoforms Enabling Resistance to CART-19 Immunotherapy Are Expressed in B-ALL Patients at Initial Diagnosis.

2017

Supplemental Digital Content is available in the text.

0301 basic medicineMaleCancer Researchmedicine.medical_treatmentT-LymphocytesEpitopes T-LymphocyteT-Cell Antigen Receptor SpecificityImmunotherapy AdoptiveEpitopeCohort StudiesExon0302 clinical medicineimmune system diseasesImmunology and AllergyMedicineProtein IsoformsChildAged 80 and overbiologyCD19CART-19B-ALLMiddle AgedPrecursor Cell Lymphoblastic Leukemia-Lymphomaepitope-lossmedicine.anatomical_structureTreatment Outcome030220 oncology & carcinogenesisChild PreschoolComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleClone (B-cell biology)Gene isoformAdultAdolescentRecombinant Fusion ProteinsImmunologyAntigens CD19Receptors Antigen T-CellCancer VaccinesCD1903 medical and health sciencesYoung AdultAntigenHumansAgedPharmacologybusiness.industryInfant NewbornisoformsInfantImmunotherapy030104 developmental biologyImmunologybiology.proteinClinical StudyTumor EscapeBone marrowbusinessJournal of immunotherapy (Hagerstown, Md. : 1997)
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Endothelial GLP-1 (Glucagon-Like Peptide 1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension

2019

Supplemental Digital Content is available in the text.

0301 basic medicineMalemedicine.medical_specialtyhypertensionBlotting WesternInflammationBlood Pressure030204 cardiovascular system & hematologyangiotensin IImedicine.disease_causeGlucagon-Like Peptide-1 Receptor1005403 medical and health sciencesMice0302 clinical medicine10030Internal medicinemedicineoxidative stressAnimalsHypoglycemic AgentsReceptor10111Cells CulturedMice KnockoutliraglutideLiraglutidebusiness.industryBasic SciencesType 2 Diabetes MellitusEndothelial CellsAtherosclerosisGlucagon-like peptide-1Angiotensin II3. Good healthMice Inbred C57BLDisease Models Animal030104 developmental biologyEndocrinology10040inflammationComputingMethodologies_DOCUMENTANDTEXTPROCESSINGRNAmedicine.symptomCardiology and Cardiovascular Medicinebusiness10024Oxidative stressmedicine.drug
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Author Correction: The genetic prehistory of the Baltic Sea region.

2018

While the series of events that shaped the transition between foraging societies and food producers are well described for Central and Southern Europe, genetic evidence from Northern Europe surrounding the Baltic Sea is still sparse. Here, we report genome-wide DNA data from 38 ancient North Europeans ranging from ~9500 to 2200 years before present. Our analysis provides genetic evidence that hunter-gatherers settled Scandinavia via two routes. We reveal that the first Scandinavian farmers derive their ancestry from Anatolia 1000 years earlier than previously demonstrated. The range of Mesolithic Western hunter-gatherers extended to the east of the Baltic Sea, where these populations persis…

0301 basic medicineMultidisciplinaryHistoryScienceQGeneral Physics and AstronomyGeneral ChemistryGeneral Biochemistry Genetics and Molecular BiologyGenealogyArticlePrehistory03 medical and health sciences030104 developmental biologyWork (electrical)Baltic seaComputingMethodologies_DOCUMENTANDTEXTPROCESSINGlcsh:Q14. Life underwaterlcsh:ScienceNature communications
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Design and protocol of Estrogenic Regulation of Muscle Apoptosis (ERMA) study with 47 to 55-year-old women's cohort : novel results show menopause-re…

2018

Supplemental Digital Content is available in the text

0301 basic medicineOncologyestradiolivaihdevuodetNeutrophilsBlood count0302 clinical medicineSurveys and QuestionnairesFSHLongitudinal Studiesmenopausal status2. Zero hungerEstradiolvalkosolutApplied MathematicsObstetrics and Gynecologyta3141ta3142Middle AgedMenstruation3. Good health17β-EstradiolMenopauseCohortComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleMenopauselihaskuntoestrogeenitmedicine.medical_specialtyGeneral MathematicsAffect (psychology)Statistics Nonparametric03 medical and health sciencesohjelmoitunut solukuolema17b-Estradiolneutrophil-to-lymphocyte ratioInternal medicinemedicineHumansLymphocyte CountAnalysis of VarianceChi-Square Distributionbusiness.industryOriginal Articlesleucocyte countmedicine.diseaseCross-Sectional Studies030104 developmental biologyApoptosisMultivariate AnalysisLinear Modelsblood viscosityFollicle Stimulating Hormonebusiness030217 neurology & neurosurgeryFollow-Up StudiesHormoneMenopause: The Journal of The North American Menopause Society
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Response to I. Batinic-Haberle et al.

2016

Letter to the editor.-- et al.

0301 basic medicinePhysiologybusiness.industryChemistryClinical BiochemistryCell Biologycomputer.software_genreBiochemistry03 medical and health sciences030104 developmental biologyComputingMethodologies_DOCUMENTANDTEXTPROCESSINGGeneral Earth and Planetary SciencesArtificial intelligencebusinessMolecular BiologycomputerNatural language processingGeneral Environmental ScienceAntioxidants & Redox Signaling
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