Search results for "Dome"
showing 10 items of 2031 documents
Synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design.
2018
Abstract Three types of ionically crosslinked (with citric acid) chitosan discs were loaded with the highly water- soluble drug, sodium salicylate (SS) and the poorly water-soluble drug, indomethacin (Ind). In separate experiments the hydrated discs were immersed in a de-crosslinking solution comprising of different concentrations of calcium chloride, which induced a controlled erosion of the discs, a process which was optimized to synchronize the release rates of the two drugs over a predetermined period of time. The optimization was accomplished by manipulating six factors: chitosan MW, its amount in the formulation, the concentration of the crosslinker agent, the concentration of the de-…
Implicación de las quimoquinas IL-8, MCP-1, rantes, los receptores CXCR1, CXCR4, CCr2, CCr5 y el factor IGFBP-rP1 en la interfase materno-embrionaria
2003
La implantación embrionaria es la fijación del blastocisto al endometrio materno. El conocimiento de los factores moleculares implicados en su regulación es crucial para comprender los mecanismos que controlan la reproducción humana Las quimoquinas y sus receptores participan activamente en este proceso así como otros factores como IGFBP-rP1.Los objetivos principales de la tesis doctoral fueron los siguientes - Investigar la expresión y localización de la quimoquinas IL-8, MCP-1, RANTES y SDF-1 en el endometrio humano.- Estudiar la expresión y localización de los receptores de las quimoquinas antes citadas CXCR1, CCR2b, CCR5 y CXCR4 en el endometrio humano.- Determinar la presencia de dicho…
Public policy in families and successions regulations : the case of ?talaq?
2021
According to EU Regulations on transnational families and successions, a foreign rule remains without effect if it is deemed contrary to the so-called public policy (ordre public) of the forum?s legal system. As a consequence, judges have to evaluate whether the application of foreign law is incompatible with fundamental principles of the domestic law, especially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq): two contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is.
Law and morals in the application of the public policy exception under the twin regulations 1103 and 1104 of 2016
2021
This paper discusses the interactions between fundamental principles of domestic legal systems and non-legal standards in the application of the public policy Generalklausel within the context of the twin Regulations 1103 and 1104 of 2016. In particular, this paper argues that public policy is composed of legal principles only and that there is no space for extra legal standards when the circulation of foreign deeds, decisions and laws is in discussion. This consideration has two consequences. Firstly, the role of good morals within contemporary private international law is extremely reduc
Property and cross-border couples from the perspective of European regulation
2021
The family property regimes constitute a relevant sector of the EU regulatory framework strongly connected with fundamental rights policies. Family property offers specific issues which need to balance individual rights with general interests, especially in matter of real estate property. The fragmentation of the discipline in EU Family law, the diversity of the domestic rules regarding rights in rem requires a large use of flexibility from EU legislator and EU legal professionals. The discipline provides by EU Regulations 1103 and 1104/2016 could be an interesting example to manage cross-border couple?s interests: the principles of universality and unity have to be used appropriately and, …
Latvijas Vēstures Institūta Žurnāls. 2011, Nr. 2 (79)
2011
Valsts kultūrkapitāla fonds; Valsts pētījuma programma "Nacionālā identitāte: valoda, Latvijas vēsture, kultūra un cilvēkdrošība"
Procesuālais taisnīgums
1998
Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy
2019
The pathogenesis of glaucoma is strongly associated with the occurrence of autoimmune-mediated loss of retinal ganglion cells (RGCs) and additionally, recent evidence shows that specific antibody-derived signature peptides are significantly differentially expressed in sera of primary-open angle glaucoma patients (POAG) compared to healthy controls. Synthetically antibody-derived peptides can modulate various effector functions of the immune system and act as antimicrobial or antiviral molecules. In an ex vivo adolescent glaucoma model, this study, for the first time, demonstrates that polyclonal-derived complementarity-determining regions (CDRs) can significantly increase the survival rate …
The European Regional Convergence Process, 1980-1995: Do Spatial Regimes and Spatial Dependence Matter?
2002
International audience; The authors show that spatial dependence and spatial heterogeneity matter in the estimation of the ß-convergence process among 138 European regions over the 1980 to 1995 period. Using spatial econometrics tools, the authors detect both spatial dependence and spatial heterogeneity in the form of structural instability across spatial convergence clubs. The estimation of the appropriate spatial regimes spatial error model shows that the convergence process is different across regimes. The authors also estimate a strongly significant spatial spillover effect: the average growth rate of per capita GDP of a given region is positively affected by the average growth rate of …