Search results for "Dominant"

Infertility in adults with polycystic kidney disease.

2002

Biproportion et offre dominante (A propos de l'article d'André Torre ‘Sur la signification théorique du modèle d'offre multisectoriel')

1996

One replies here to partisans of the reject of the supply-driven model in input-output analysis and especially to A. Torre (Revue Economique, 5, 44, 951-970). First of all, demand-driven hypothesis (Leontief) and supply-driven hypothesis (Ghosh) are symmetrical and incompatible, what forbidden to reject the second to the motive that it depends on the first. Secondly, the results earlier obtained for France of 1970 to 1985 from the method of the biproportionnal filter show that there is so much instability in the long term in the columns than in the rows of the flow matrix. Thirdly, the assimilation of the usage of allocation coefficients to the adoption of the supply-side model is excessive.

Social media e comunicazione fatica: verso una tipologia delle pratiche in rete

2017

Social media and fatic communication: toward a typology of practices in the web. It is often said that the communicative functioning of social networks is based on the “fatic function” of language and, in general, of semiosis. The purpose of this paper is to clarify the conceptual meaning of this notion, returning to the fundamental authors who have coined it; and therefore to show its relationships with the referential function, on the one hand, and the expressive one, on the other. Hence, another aim of the paper is sketch a typology of facebook users, halfway between desire to share and self-construction project.

Exploring the common blockchain adoption enablers: the case of three Italian wineries

2021

Purpose This study aims to explore and describe the main enabling factors affecting the implementation of blockchain technology (BCT) in a strategic sector such as the wine industry, as well as the motivation behind this choice. Design/methodology/approach In light of the novelty of the phenomenon studied, a case study approach was adopted analyzing three Italian wineries. A conceptual framework, based on the dynamic capabilities, absorptive capacity and dominant logic theories, was developed. Primary and secondary data were collected. Findings Results show that wineries working in a highly dynamic and competitive market invest more in knowledge acquisition and internal assimilation and le…

Volatiles in pantellerite magmas: A case study of the Green Tuff Plinian eruption (Island of Pantelleria, Italy)

2013

Abstract The Green Tuff (GT) Plinian eruption, the largest in magnitude at Pantelleria, erupted 3 to 7 km3 DRE of pantellerite magma and a small volume of trachyte. Fifty-nine anorthoclase-hosted melt inclusions from the two basal pumice members were analyzed by FT-IR spectroscopy in order to assess the pre-eruptive H2O content in the pantellerite melt. Microanalytical methods were used to determine major element, Cl, F and S contents. Melt inclusions and glassy groundmasses have a nearly homogeneous pantelleritic composition (peralkaline index = 1.9-2.2) and variable water contents ranging from 1.4 to as high as 4.2 wt %, i.e. much higher than the 1.4 wt % of earlier published studies. The…

The amide of galacturonic acid with lysine as an immunodominant component of the lipopolysaccharide core region from Proteus penneri 42 strain

2014

Most Proteus lipopolysaccharides (LPSs) contain uronic acids or their amides with different amino acids, which together with other negatively charged components account for the acidic character of such LPS molecules. Previous studies have shown the significance of an amide of galacturonic acid with lysine [D-GalA(L-Lys)] for serological specificity of O-antigens from few P. mirabilis strains. In this work, the immunodominant role of GalALys was indicated for the P. penneri 42 LPS core region. The studies also showed the serological identity of core oligosaccharides from P. penneri 42 (O71), P. mirabilis 51/57 (O28) and R14/S1959 strains. from P. penneri 42 (O71), P. mirabilis 51/57 (O28) an…

Translations, Paratextual Mediation, and Ideological Closure

1996

Abstract: This article deals with the way so-called paratexts were used, in Finland in 1890-1939, in publishing translations of Anglo-American literature, and especially with the tendencies towards ideological closure that those paratexts manifest. The dominant ideology in the material is what could be called religious-conservative ideology, emphasizing the thought content of the works and their (educative, civilizing, sometimes also entertaining) impact on readers. This is due to the ideological unification process that penetrated the cultural institutions, which were still relatively undifferentiated and non-autonomous during the period in Finland. The article emphasizes that in studying …

WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome

2018

International audience; Locus heterogeneity characterizes a variety of skeletal dysplasias often due to interacting or overlapping signaling pathways. Robinow syndrome is a skeletal disorder historically refractory to molecular diagnosis, potentially stemming from substantial genetic heterogeneity. All current known pathogenic variants reside in genes within the noncanonical Wnt signaling pathway including ROR2, WNT5A, and more recently, DVL1 and DVL3. However, ∼70% of autosomal-dominant Robinow syndrome cases remain molecularly unsolved. To investigate this missing heritability, we recruited 21 families with at least one family member clinically diagnosed with Robinow or Robinow-like pheno…

Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 (SCA10) expansions

2017

Spinocerebellar ataxia type 10 (SCA10), an autosomal dominant cerebellar ataxia disorder, is caused by a non-coding ATTCT microsatellite repeat expansion in the ataxin 10 gene. In a subset of SCA10 families, the 5'-end of the repeat expansion contains a complex sequence of penta- and heptanucleotide interruption motifs which is followed by a pure tract of tandem ATCCT repeats of unknown length at its 3'-end. Intriguingly, expansions that carry these interruption motifs correlate with an epileptic seizure phenotype and are unstable despite the theory that interruptions are expected to stabilize expanded repeats. To examine the apparent contradiction of unstable, interruption-positive SCA10 e…

Homozygous Familial Hypercholesterolemia in Spain Prevalence and Phenotype-Genotype Relationship

2016

Background— Homozygous familial hypercholesterolemia (HoFH) is a rare disease characterized by elevated plasma levels of low-density lipoprotein cholesterol (LDL-C) and extremely high risk of premature atherosclerotic cardiovascular disease. HoFH is caused by mutations in several genes, including LDL receptor ( LDLR ), apolipoprotein B ( APOB ), proprotein convertase subtilisin/kexin type 9 ( PCSK9 ), and LDL protein receptor adaptor 1 ( LDLRAP1 ). No epidemiological studies have assessed HoFH prevalence or the clinical and molecular characteristics of this condition. Here, we aimed to characterize HoFH in Spain. Methods and Results— Data were collected from the Spanish Dyslipidemia Regist…