Search results for "Dominant"

Reakcia dubov voči klimatickým extrémom v prechodnej zóne dubových a bukových lesov

2021

Forest management might be threatened by declining health status of oaks in the transition zone between oak and beech forests, where drought is the most limiting factor. The aim of the presented paper is to assess the influence of selected climatic characteristics on the radial growth of oak trees with different stem diameter status in the beech-oak and oak-beech forest altitudinal zones within the forest growth area of Poľana Mt. and Zvolen Basin (Slovakia). Our results show that oaks with less favourable stem diameter position (Weisse’s middle stems) show slower radial growth, have less pronounced climatic precipitation signal and milder response to extreme climatic events. The findings p…

Economic Concentrations vs State of Competitive Space

2017

Achieving market performance is the main objective of companies in business transactions. Developing competitiveness and gaining a large market share is conditional on achieving the proposed objectives. A way to increase the market power is to do mergers or takeovers. They can be vertical or horizontal, depending on the type of activity realized by the parties. Effects resulting from the economic mergers made under certain conditions, can distort the competitive environment on the market, with a serious damage. This leads to the need to analyze them in the compatibility with the competitive environment. Permission to achieve a merger occurs after a comprehensive study of cases considering t…

The care pathway for children with urticaria, angioedema, mastocytosis

2015

Cutaneous involvement characterized by urticarial lesions with or without angioedema and itch is commonly observed in routine medical practice. The clinical approach may still remain complex in real life, because several diseases may display similar cutaneous manifestations. Urticaria is a common disease, characterized by the sudden appearance of wheals, with/without angioedema. The term Chronic Urticaria (CU) encompasses a group of conditions with different underlying causes and different mechanisms, but sharing the clinical picture of recurring wheals and/or angioedema for at least 6 weeks. Hereditary Angioedema (HAE) is a rare disorder characterized by recurrent episodes of non-pruritic,…

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

2019

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this "convergence" of adaptive immunity among different individuals remain poorly understood. To quantitatively describe epitope immunogenicity, here we propose a supervised machine learning framework generating probabilistic estimates of immunogenicity, termed "immunogenicity scores," based on the numerical features computed through sequence-based simulation approximating the molecular scanning process of peptides presented onto major histocompatibility complex (MHC) by the human T cell receptor (T…

Political Shakespeare and the Blessing of Art

2018

This text attempts to detail the functions and effects of some of Shakespeare's aesthetic strategies, and to determine their relationship to ideology. While this is critical territory that cultural materialists and new historicists have extensively mapped, the current text avoids the preferred methods of enquiry that these lines take. Rather than giving focus to the containment strategies of a dominant ideology, my investigation proceeds via a close reading of certain elements from Act 5 of Shakespeare's A Midsummer Night's Dream. I attempt to demonstrate that meaning in the play is determined and encompassed within the self-reflective and dissimulating structures of Shakespeare's art. I su…

Optimizing the use of linaclotide in patients with constipation-predominant irritable bowel syndrome : an expert consensus report

2017

INTRODUCTION: Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by chronic or recurrent abdominal pain in association with defecation or a change in bowel habits. A predominant disorder of bowel habits, IBS is classified into three main subtypes: constipation-predominant IBS (IBS-C), diarrhea-predominant IBS (IBS-D) and IBS alternating between constipation and diarrhea (IBS-M). Linaclotide is a first-in-class, oral, once-daily guanylate cyclase-C receptor agonist (GC-CA) that is licensed for the symptomatic treatment of moderate-to-severe IBS-C in adults. This review aims to facilitate and optimize clinical practices, establishing common guidelines to monitor patie…

Motor asymmetry attenuation in older adults during imagined arm movements

2014

International audience; Laterality is an important feature of motor behavior. Several studies have shown that lateralization in right-handed young adults (i.e., right versus left arm superiority) emerges also during imagined actions, that is when an action is internally simulated without any motor output. Such information, however, is lacking for elderly people and it could be valuable to further comprehend the evolution of mental states of action in normal aging. Here, we evaluated the influence of age on motor laterality during mental actions. Twenty-four young (mean age: 24.7 +/- 4.4 years) and 24 elderly (mean age: 72.4 +/- 3.6 years) participants mentally simulated and actually execute…

Role of Renin-Angiotensin-Aldosterone System and of Sympathetic Activity in Arterial Hypertension Associated with Autosomal Dominant Polycystic Kidne…

1997

Efecto del estiramiento miocárdico sobre las frecuencias de activación determinadas mediante análisis espectral durante la fibrilación ventricular

2002

Introduction and objectives. The aim of this study was to analyze the effects of myocardial stretching on excitation frequencies, as determined by spectral analysis, during ventricular fibrillation. Methods. In 12 isolated rabbit heart preparations, ventricular activation during ventricular fibrillation was recorded with multiple electrodes. Recordings were obtained before, during and after ventricular dilatation produced with an intraventricular balloon. The dominant frequency of the signals obtained with each of the electrodes was determined by spectral analysis. Results. During the control phase, the mean, minimum and maximum dominant frequencies were, respectively, 14.3 ± 1.7, 12.5 ± 1.…

Hereditary gingival fibromatosis: clinical and ultrastructural features of a new family

2014

Objective: This article describes the diagnosis, clinical and microscopic (histopathology and ultrastructural) features and treatment of a new family with hereditary gingival fibromatosis (HGF) and highlights the importance of this genetic condition. Study Design: To characterize the pattern of inheritance and the clinical features, members of a new family with HGF were examined. The pedigree was reliably constructed including the four latest generations of family. Hematoxylin and eosin staining and ultrastructural analysis were performed with the gingival tissue. Results: Examination of the family pedigree revealed that the patient III-2 represent the index patient of this family (initial …