Search results for "Dot"

Extracting locations from sport and exercise-related social media messages using a neural network-based bilingual toponym recognition model

2022

Funding: This study is a part of the “Equality in suburban physical activity environments, YLLI” research project (in Finnish: Yhdenvertainen liikunnallinen lähiö, YLLI). The project is being financed by the research program about suburban in Finland “Lähiöohjelma 2020-2022” coordinated by the Ministry of Environment (grant recipient: Dr. Petteri Muukkonen). Sport and exercise contribute to health and well-being in cities. While previous research has mainly focused on activities at specific locations such as sport facilities, “informal sport” that occur at arbitrary locations across the city have been largely neglected. Such activities are more challenging to observe, but this challenge may…

Cellular mechanisms of IL-17-induced blood-brain barrier disruption.

2009

Recently T-helper 17 (Th17) cells were demonstrated to disrupt the blood-brain barrier (BBB) by the action of IL-17A. The aim of the present study was to examine the mechanisms that underlie IL-17A-induced BBB breakdown. Barrier integrity was analyzed in the murine brain endothelial cell line bEnd.3 by measuring the electrical resistance values using electrical call impedance sensing technology. Furthermore, in-cell Western blots, fluorescence imaging, and monocyte adhesion and transendothelial migration assays were performed. Experimental autoimmune encephalomyelitis (EAE) was induced in C57BL/6 mice. IL-17A induced NADPH oxidase- or xanthine oxidase-dependent reactive oxygen species (ROS)…

Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patie…

2014

Introduction Particularly in the setting of acute coronary syndromes, the interplay between vascular and platelet function has been postulated to have direct clinical implications. The present trial is designed to test the effect of clopidogrel, prasugrel and ticagrelor on multiple parameters of vascular function, platelet aggregation, oxidative and inflammatory stress before and up to 4 weeks after coronary artery stenting. Methods and analysis The study is designed as a three-arm, parallel design, randomised, investigator-blinded study. Patients with unstable angina or non-ST elevation myocardial infarction undergoing coronary intervention with a drug-eluting stent will be randomised to r…

Kustību rotaļa kā pārvietošanās pamatkustību pilnveidotāja 2-3 gadus veciem bērniem

2021

Nosaukums: Kustību rotaļa kā pārvietošanās pamatkustību pilnveidotāja 2-3 gadus veciem bērniem. Autore: Marina Stražinska Zinātniskā darba vadītāja: Mg. izgl. zin. Agita Klempere- Sipjagina Šajā kvalifikācija darbā tika teorētiski pētīta kustību rotaļa kā pārvietošanās pamatkustību pilnveidotāja pirmsskolā. Tika izpētīta konkrētā vecuma posma bērna attīstība un attīstības īpatnības. Darba pirmā nodaļa teorētiski raksturotas pamatkustības. Otrajā nodaļā teorētiski raksturotas 2-3 gadus vecu bērnu psiho-fizioloģiskās attīstības īpatnības. Trešajā nodaļā tika teorētiski pētīta rotaļu būtība un kustību rotaļas nozīme 2-3 gadus vecu bērnu pamatkutību pilnveidošana. Empīriskajā pētījumā tika izzi…

Avaimet osaamiseen ja tulevaisuuteen : selvitys maahanmuuttajataustaisten nuorten osaamisesta ja siihen liittyvistä taustatekijöistä PISA 2012 -tutki…

2014

Cardiometabolic Alterations in the Interplay of COVID-19 and Diabetes: Current Knowledge and Future Avenues

2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019 [COVID-19]) pandemic has raged for almost two years, with few signs of a sustained abatement or remission [...]

Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena?

2020

Opettaja tulevaisuuden taitojen edistäjänä : "jos haluat opettaa noita taitoja, sinun on ensin hallittava ne itse"

2013

Luminescent CdSe Quantum Dot Arrays for Rapid Sensing of Explosive Taggants

2022

Chemical sensors based on fluorescent quantum dots have attracted intense interest because of their excellent optical and electronic properties compared to the routinely employed fluorescent organic dyes. This study reports a CdSe QD-polymer-based luminescent chemosensor, which is based on an array containing either green-emitting or red-emitting CdSe QDs embedded in polycaprolactone as a polymer host matrix. We evaluate the sensing capability of the nanocomposites by exposing both sensors to vapors of explosive taggants, explosive-like molecules, and some common solvents. Both nanocomposites exhibit a very fast response time of <30 s. The limit of detection of the sensors for 3-nitrotoluen…

Hyaluronic acid and alpha-elastin based hydrogel for three dimensional culture of vascular endothelial cells

2018

Abstract The aim of this work was to demonstrate that employing a copolymer of hyaluronic acid and α-elastin (HA-EDA-g-α-elastin) is possible to produce a scaffold able to support the adhesion and growth of human vascular endothelial cells (HUVEC) thanks to its ability to incorporate and control the diffusion of vascular endothelial growth factor (VEGF). HA-EDA-g-α-elastin was crosslinked with low molecular weight hyaluronic acid (HALMW) to obtain a hydrogel that gives rise to the formation of three dimensional sponge after the freeze drying process. The physicochemical features the obtained material along with its ability to act as a support for the three dimensional culture of endothelial…