Search results for "Dote"
showing 10 items of 164 documents
Identification of mixed bromidochloridotellurate anions in disordered crystal structures of (bdmim)2[TeX2Y4] (X, Y = Br, Cl; bdmim = 1-butyl-2,3-dime…
2014
The discrete mixed [TeBrxCl6−x]2− anions in their disordered crystal structures have been identified by using the phases prepared by the reaction of 1-butyl-2,3-dimethylimidazolium halogenides (bdmim)X with tellurium tetrahalogenides TeX4 (X = Cl, Br) as examples. Homoleptic (bdmim)2[TeX6] [X = Cl (1), Br (2)] and mixed (bdmim)2[TeBr2Cl4] (3), and (bdmim)2[TeBr4Cl2] (4) are formed depending on the choice of the reagents, and their crystal structures have been determined by single-crystal X-ray diffraction. The coordination environments of tellurium in all hexahalogenidotellurates are almost octahedral. Because of the crystallographic disorder, the mixed [TeBr2Cl4]2− and [TeBr4Cl2]2− anions …
Suomalaisten suuryritysten vuosina 1851-1925 syntyneiden johtajien elinikä
2012
Tässä työssä tarkastellaan suomalaisten teollisuusyritysten johtajien kuolleisuutta. Tarkoituksena on selvittää sosioekonomisia kuolleisuuseroja 1900-luvun alusta alkaen vertailemalla johtajien kohorttikuolleisuutta miesten yleiseen kohorttikuolleisuuteen vastaavana aikana. Aineiston 192 johtajaa ovat syntyneet vuosina 1851–1925 ja toimineet johtajina vuosien 1900 ja 1975 välisenä aikana. Kuolleisuuden käsittelyssä käytetään kolmea mittaria: saavutettua elinikää, aikuisiän elinajanodotetta ja johtajakohtaisesti laskettua todennäköisyyttä väestön yleiselle edustajalle elää johtajan nimityshetkestä vähintään yhtä pitkään kuin johtaja. Lisäksi luodaan nopea katsaus johtajien kuolemiseen vielä …
Predictors of mortality in old age : contribution of self-rated health, physical functions, life satisfaction and social support on survival among ol…
2006
Length of life is perhaps the best single indicator of the health of a population. The purpose of the present series of studies was to explore the potential predictors of mortality in older people with special emphasis on self-rated health, physical functions, life satisfaction and perceived social support.The four studies used prospective data drawn from 1) the Evergreen study, where mortality was followed for 10 years in an entire cohort of the 75- and 80-year-old (N=650) residents of the city of Jyväskylä, Finland, 2) the Functional capacity of men born in 1906-10, 1926-30 and 1946-50 research project from which two oldest age cohorts, 257 residents of the city of Jyväskylä, Finland aged…
Significado pronóstico de la expresión del factor de crecimiento endotelial vascular (VEGF) y de genes implicados en las vías de señalización del VEG…
2022
El estudio de las características de la leucemia aguda mieloblástica (LMA) al diagnóstico es fundamental porque clasifica a los pacientes en grupos pronósticos para adaptar el tratamiento al riesgo de recaída y reducir la toxicidad. Sin embargo, existe un grupo de pacientes en los que no se detectan alteraciones citogenéticas o moleculares y cuya evolución es muy heterogénea. Diversos estudios han demostrado un aumento de la angiogénesis en la médula ósea de los pacientes con LMA así como de citoquinas proangiogénicas como el factor de crecimiento endotelial vascular (VEGF). Las células leucémicas inducen la angiogénesis a través del VEGF, que regula la proliferación, supervivencia, angiogé…
Tēva loma anekdotēs mūsdienās un tradicionālās folkloras aspektā
2015
Bakalaura darba "Tēva loma anekdotēs mūsdienās un tradicionālās folkloras aspektā" mērķis ir noskaidrot tēva nozīmi ģimenē tradicionālajā folklorā un tā iespējamo lomas maiņu mūsdienu folklorā anekdošu aspektā. Tēva tēls līdz šim ir mazāk apskatīts nekā mātes tēls, kas ir pētīts saistībā, piemēram, ar māšu kultu vai mātes ciešo sakaru ar bērnu. Arī aplūkojot citus folkloras tēlus, kas saistīti ar latviešu tradicionālo ģimenes modeli, tēvs nav apskatīts kā indivīds, nav izceltas viņa darbības vai ietekmes sfēras ģimenē, nav nodalīti viņa tiešie ģimenes pienākumi, kas šajā darbā tika izdarīts. Lai sasniegtu darba mērķi, tika izvirzīti šādi uzdevumi: •Noskaidrot ģimenes terminu, aplūkot latvie…
Vascular aging in women: is estrogen the fountain of youth?
2012
Aging is a physiological process associated with structural and functional changes in vasculature, including endothelial dysfunction, arterial stiffening and remodeling, impaired angiogenesis, and defective vascular repair, and with an increasing prevalence of atherosclerosis. The risk of cardiovascular disease differs between men and women, remaining lower in women during their fertile years and reaching values similar to their male peers after menopause. Menopause is marked by the loss of endogenous estrogen production. Therefore, estrogens have been implicated in premenopausal protection from cardiovascular disease, an assumption supported by experimental and some clinical studies, where…
Suizidale und parasuizidale Intoxikationen mit Paracetamol
2003
BACKGROUND AND OBJECTIVE: Paracetamol is frequently used in deliberate self-poisoning resulting in a major risk for the patients due to its dose-dependent hepatotoxicity. In the present study the cases of intoxications consulting our Poison Center should be analysed illustrating recent results and trends. PATIENTS AND METHODS: From 38 065 patients (25 098 female, 12447 male, 520 sex unknown, average age 36.8 years) registered during the study period from 1.1.1995 until 31.5.2002 4021 with paracetamol intoxication were analysed with respect to the ingested dose, concomitant substances, the degree of observed symptoms and the length of hospital stay. RESULTS: The use of paracetamol in deliber…
Estradiol, acting through estrogen receptor alpha, restores dimethylarginine dimethylaminohydrolase activity and nitric oxide production in oxLDL-tre…
2011
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthase. ADMA accumulation, mainly due to a decreased dimethylarginine dimethylaminohydrolase (DDAH) activity, has been related to the development of cardiovascular diseases. We investigate whether estradiol prevents the changes induced by oxidized low density lipoprotein (oxLDL) on the DDAH/ADMA/NO pathway in human umbilical artery endothelial cells (HUAEC). HUAEC were exposed to estradiol, native LDL (nLDL), oxLDL and their combinations for 24 h. In some experiments, cells were also exposed to the unspecific estrogen receptor (ER) antagonist ICI 182780, the specific ERα antagonist MPP or specific agonists …
Nitric oxide and sensory afferent neurones modulate the protective effects of low-dose endotoxin on rat gastric mucosal damage
1995
Pretreatment (1 h) with low doses (5-40 micrograms/kg i.p.) of Escherichia coli endotoxin dose dependently reduced the gastric mucosal damage induced by a 10 min challenge with 1 ml ethanol (50% and 100%) in conscious rats. Treatment with the nitric oxide synthesis inhibitor, NG-nitro-L-arginine methyl ester (L-NAME, 5 and 10 mg/kg i.p.), significantly inhibited the protective effects of endotoxin (40 micrograms/kg i.p.). The actions of L-NAME were reversed by the prior administration of L-arginine (100 mg/kg i.p.). The protective effects of endotoxin were not influenced by pretreatment with dexamethasone (5 mg/kg s.c. twice) or indomethacin (5 mg/kg s.c.). However, ablation of sensory affe…
Estudio de la acción proinflamatoria de Angiotensina II y su posible modulación. Papel de Angiotensina II en disfunciones endoteliales.
2002
La acumulación leucocitaria es una característica de los primeros estadios de la lesión aterosclerótica, de infarto agudo de miocardio y de enfermedades renales de diversa etiología. Receptores para Angiotensina-II (Ang-II) han sido hallados en monocitos y Ang-II puede promover la activación y adhesión de estas células. Este proceso podría desencadenar o perpetuar el daño endotelial asociado a aterosclerosis e hipertensión. Los resultados de nuestro estudio demuestran que Ang-II, a dosis subvasoconstrictoras y fisiológicas, presenta propiedades proinflamatorias in vivo a nivel agudo; en concreto, produce acumulación leucocitaria en vénulas de la microcirculación mesentérica de la rata a tra…