Search results for "Drug utilization"
showing 10 items of 34 documents
Antiepileptic drug use in nursing home residents: a cross-sectional, regional study.
2006
Summary The use of antiepileptic drugs (AED), their primary indication, comorbid conditions, and concomitant medications were collected from 565 nursing homes (NH) residents of six NH located around the city of Mainz, Germany representing 5.05% of all NH residents in the area. Data were collected from the electronic pharmacy files and by reviewing all available medical records. Average age was 82.2±2.4 years, 85.5% were women. Of 565 NH residents 28 (4.96%) received AED therapy, of which in 17 (63%) AED were prescribed for a seizure-related diagnosis. In 76.5% seizure types were unspecified and a distinction in focal and generalized epilepsy was made in only 23.5% of patients. Three patient…
Why are our patients still suffering pain?
2007
Legal barriers, restricted resources, lack of physician training, and physician and patient worries about potential opioid addiction can be barriers to effective and rational pain management in patients with cancer pain. Sebastiano Mercadante discusses these issues, as well as suggesting interventions for improving care.
From Global Initiative for Chronic Obstructive Lung Disease (GOLD) Guidelines to Current Clinical Practice
2006
Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines have been promulgated to improve the management of chronic obstructive pulmonary disorder (COPD). Objective: To evaluate the extent to which the current therapeutic approach to COPD conforms to GOLD guidelines. Methods: This was a multicentre observational study of elderly COPD patients enrolled for acute care in general medicine or geriatric wards in tertiary hospitals in Italy in April 2002. Our series consisted of 471 patients >64 years of age consecutively admitted for acute exacerbations of COPD to wards participating in the study. Data describing drugs used prior to exacerbation and prescribed at …
A prospective study of adverse drug reactions as a cause of admission to a paediatric hospital
1996
1A total of 512 consecutive paediatric hospital admissions of children 2 years old or less were evaluated to assess the extent and pattern of admission caused by suspected adverse drug reactions (ADRs). The proportion of suspected ADRs related to hospital admissions was 4.3%. 2The organ-systems most commonly implicated were the central nervous system (40.5%), digestive system (16.7%), and skin and appendages (14.3%). Together, they accounted for 71.5% of admissions attributed to ADRs. The most common clinical manifestations inducing admission were convulsions (4 cases), dizziness (4), vomiting (3), and tremor, fever, itching and apnoea (2 cases each). 3The four classes of drugs most frequen…
Uso de medicamentos associados ao risco de quedas em idosos não institucionalizados
2018
RESUMEN Objetivo: Determinar qué número de medicamentos consumidos diariamente es influyente en el riesgo de caídas en ancianos no institucionalizados y con historial de caídas en el último año. Método: Estudio descriptivo mediante muestreo aleatorio con la utilización de los siguientes instrumentos de medida: cuestionario de la OMS para el estudio de caídas en el anciano, escala de marcha y escala depresión geriátrica y escala de marcha y equilibrio. El análisis univariante, bivariante con prueba no paramétrica de Chi-cuadrado y regresión logística binaria se ellevó a cabo con el programa estadístico SPSS versión 21.0. Resultados: Participaron del estudio 213 personas. El consumo ≥ a 4 med…
Pharmacological treatment of sexual offenders in German outpatient treatment centers
2018
In Germany, depending on a sexual offender's culpability and the severity of the offence, he/she can be placed either in the forensic-psychiatric or the correctional system. Numbers related to the pharmacological treatment of sexual offenders for the correctional system are missing so far. In sexual offenders, the pharmacological treatment of paraphilic disorders is of special importance. The present study aimed at assessing the prevalence of pharmacological sexual offender treatment in German outpatient treatment centers supervising mainly clients from the correctional sector. An online questionnaire was sent to 112 outpatient treatment centers and 21 provided data relevant for the present…
The use of proton pump inhibitors in an Italian hospital: focus on oncologic and critical non-ICU patients
2015
Background Proton pump inhibitors (PPIs) are among the most misused drugs both at the community and hospital level. Recently, possible risks have been underscored, suggesting the importance of limiting PPI use to proven indications. Objective To survey the appropriateness of PPI use in a University hospital in Italy. Setting Azienda Ospedaliera Universitaria Policlinico ‘P. Giaccone’, in Palermo, Italy. Method A one day-observational study, reviewing patients’ medical records to identify treatments with PPIs and the indications for their use. After discharge, a subgroup of the cohort was followed up to assess the continuation of therapy at home. Appropriateness was evaluated according to th…
The use of low molecular weight heparin in a Sicilian teaching hospital
2013
LMWH are replacing unfractionated heparin (UFH) for therapeutic anticoagulation owing to their more predictable pharmacokinetics and ease of use. Especially in Sicily, their prescription volume is steadily increasing in general practice, but little is known about their use in the hospital setting. We investigated LMWH use at the Policlinico Universitario P. Giaccone of Palermo by examining the records of drug dispensation to the wards in the years 2010-2012. From 2010 to 2012 the use of LMWH at Policlinico of Palermo remained stable with a mean of 71 DDD/100 bed days (range 69-73) of drugs dispensed. Enoxaparin, nadroparin and reviparin were the most prescribed molecules, accounting each on…
Évaluation de la prescription des antalgiques de palier II chez la personne âgée de 75 ans en médecine générale
2017
Although step-2 analgesics (S2A) are recommended when step-1 analgesics (S1A) are ineffective or in cases of moderate to severe pain, their efficacy varies. This study evaluated the place attributed by general practitioners (GPs) to S2A in the treatment of nociceptive pain in elderly persons (EP). Descriptive, transversal and declarative study conducted among GPs in Burgundy. In total, 115 GPs took part in the survey. Among these, 60.8% had at least one consultation/day for pain. After paracetamol, which was systematically preferred, 56.4% prescribed S2A for EP. The reasons for prescribing S2A included pain not relieved by S1A in 93% of cases, another medical treatment or not (42.6%), or th…
Duration of first-line antiretroviral therapy with tenofovir and emtricitabine combined with atazanavir/ritonavir, efavirenz or lopinavir/ritonavir i…
2013
Objectives: To explore the durability of three first-line tenofovir/emtricitabine-based regimens in combination with atazanavir/ritonavir, efavirenz or lopinavir/ritonavir in HIV-1-infected patients. Patients and methods: A retrospective, longitudinal, multicentre analysis of adult patients enrolled in the Antiretroviral Resistance Cohort Analysis (ARCA), a national prospective observational cohort of HIV-1-infected patients followed up at more than 100 clinical and laboratory units in Italy. Patients eligible were those starting first-line antiretroviral therapy between 1 June 2004 and 15 April 2011 and who were followed up for at least 6 months. The primary endpoint was durability, define…