Search results for "Drying"
showing 10 items of 172 documents
Spray Freeze Dried Lyospheres® for Nasal Administration of Insulin
2021
Pharmacologically active macromolecules, such as peptides, are still a major challenge in terms of designing a delivery system for their transport across absorption barriers and at the same time provide sufficiently high long-term stability. Spray freeze dried (SFD) lyospheres® are proposed here as an alternative for the preparation of fast dissolving porous particles for nasal administration of insulin. Insulin solutions containing mannitol and polyvinylpyrrolidone complemented with permeation enhancing excipients (sodium taurocholate or cyclodextrins) were sprayed into a cooled spray tower, followed by vacuum freeze drying. Final porous particles were highly spherical and mean diameters r…
Multicomponent solid dispersion as a formulation strategy to improve drug permeation: A case study on the anti-colorectal cancer irinotecan
2019
Abstract Multicomponent solid dispersions (MSD)s are frequently proposed as efficient drug delivery systems to improve drug solubility and bioavailability. In this study, the effects of specific excipients, such as mannitol, inulin, poly(methyl methacrylate-co-methacrylic)acid (PMMA) and cellulose acetate phthalate (CAP) have been tested to potentially improve irinotecan (IRN) permeation in the intestinal tract with the intention to protect the drug from the gastric environment. MSDs were formulated as microparticles by Spray-Drying technique. Raw materials and microparticles have been characterized by FTIR analysis to determine hydrogen bonding. SEM images were recorded to investigate morp…
Influence of emulsion and powder size on the stability of encapsulated d-limonene by spray drying
2005
Abstract The microencapsulation of d -limonene by spray drying was investigated with respect to the effects of emulsion droplet size, powder particle size, as well as to the effects of various kinds of matrices (gum arabic, maltodextrin, and modified starch) on its stability. It was realized by studying release characteristics and oxidative stability during storage. The release and the oxidation decreased deeply with an increase in powder and emulsion particle size for gum arabic and maltodextrin materials. Further, the distributions of emulsion size in the powder showed an increase in the fraction of large emulsion droplets and changed to a bimodal distribution. However, the modified starc…
Properties of spray-dried food flavours microencapsulated with two-layered membranes: Roles of interfacial interactions and water
2012
International audience; Engineering the interface of oil-in-water emulsion droplets with biopolymers that modify its permeability could provide a novel technique to improve flavour retention in dry powders. The objective of this study was to determine if volatile compounds were more retained in dry emulsions stabilized by pea protein isolate (PPI)/pectin complex than that stabilized by PPI alone. The retention of ethyl esters during spray-drying increased with decreasing volatility of the encapsulated compound and ranged from 28% to 40%. The addition of pectin to feed emulsions was quite effective in markedly improving the retention of the three studied flavour compounds. In our previous wo…
Identification of lipid binders in paintings by gas chromatography
2001
Abstract The influence of the presence and the type of pigments in the lipid binding media of paintings were studied by gas chromatography with flame ionization detector. The drying oils were linseed stand oil, poppy oil and sunflower oil, and the pigments studied were cadmium red, cobalt blue, tin white, lead white, chalk and plaster of Paris, commonly used in paintings. The results indicate that the stearic/palmitic ratio and the presence of pigments are quite stable during ageing. However, some differences in the oleic acid/palmitic acid ratio were found, depending on the type of pigment present in the lipid binding media. These variations are related to the drying effect of the pigments…
Recurrent deficit irrigation and fruit harvest affect tree water relations and fruitlet growth in ‘valencia’ orange
2019
Background – Partial rootzone drying is an irrigation strategy known for increasing water use efficiency without significantly affecting tree water status. ‘Valencia’ oranges have a very long development period and nearly mature fruit and new fruitlets may be present at the same time on the tree, competing for water and assimilates. Objectives – The present study investigates the effect of recurrent deficit irrigation and fruit harvest on tree water status and fruitlet growth of ‘Valencia’ orange. Methods – Forty-eight adult trees were exposed to three irrigation treatments for seven years (2007–2013): irrigation with 100% of ETc (CI), continuous deficit irrigation (DI, 50% of CI) and parti…
Superior Antibacterial Activity of Integral Lemon Pectin Extracted via Hydrodynamic Cavitation
2020
Abstract Pectin extracted via hydrodynamic cavitation in water only from waste lemon peel and further isolated via freeze drying displays significant antibacterial activity against Staphylococcus aureus, a Gram positive pathogen which easily contaminates food. The antibacterial effect of the new IntegroPectin is largely superior to that of commercial citrus pectin, opening the way to advanced applications of a new bioproduct now obtainable in large amounts and at low cost from citrus juice industry's waste.
The Effect of Intense Air Drying on Material Distribution and Quality in Coated Papers
2003
Abstract The aim of this study was to find out what will happen to paper coating quality and material gradients if coating is dried in one air dryer at a high convection rate (150 kg/m2h). Different printing papers were coated, calendered and printed with pilot machines. The binder and pigment gradients of the coated, and also printed, samples were analyzed with LIPS (Laser Induced Plasma Spectrometry). It was found that drying affects the migration of starch, but not latex. Total air drying can be used to dry printing papers, if air temperature, velocity and moisture content can be separately controlled. The control of web temperature is more important for paper quality formation in a coat…
Biodiversity and dairy traits of lactic acid bacteria from foliage of aromatic plants before and after dehydration process monitored by a smart senso…
2020
ABSTRACT The main hypothesis of this work was to evaluate the presence of lactic acid bacteria (LAB) intrinsically resistant to plant essential oils in sage (Salvia officinalis L.) and laurel (Laurus nobilis), for future applications in functional cheese production by addition of aromatic herbs. The effect of the drying process on the viability of LAB was evaluated with three biomass densities (3, 4 and 5 kg/m2). The drying densities did not affect weight loss, but influenced the levels of LAB of sage and laurel. A total of 10 different strains of Enterococcus faecium, Enterococcus mundtii, Enterococcus raffinosus and Leuconostoc mesenteroides were identified from laurel, while sage did not…
Dielectric and mechanical assessment of cellulosic insulation during transformer manufacturing
2021
Due to the impact of cellulose of paper insulation on transformer life, it is imperatire to remove moisture from the oil and the solid insulation. Several techniques have been implemented during manufacturing of power transformers to reduce water content in transformers. These drying processes can involve different costs and time, and they can damage the insulation paper. In this work, a drying process has been implemented in the laboratory trying to simulate the most aggressive conditions that can be suffered by the paper in transformer manufacturing in a real industry. Once the moisture content of papers was lower than 0.5%, the effect of the drying process on paper degradation was evalua…