Search results for "Durability"

showing 10 items of 109 documents

Durability of Dolutegravir-Based Regimens: A 5-Year Prospective Observational Study

2021

This study evaluates the frequency and causes of dolutegravir (DTG) discontinuation along 5 years of follow-up, in both antiretroviral treatment (ART)-naive and experienced people living with HIV (PLWH). This is a prospective multi-center cohort study enrolling PLWH on DTG from July 2014 until November 2020. DTG-durability was investigated using the Kaplan-Meier survival curve. The Cox proportional-hazards model was used for estimating the hazard ratio (HR) of DTG discontinuation for any cause, and for adverse events (AEs). Nine hundred sixty-three PLWH were included, 25.3% were women and 28.0% were ART-naive. Discontinuations for any causes were 10.1 [95% confidence interval (95% CI) 8.9-1…

adverse events; dolutegravir; durability; HIV; safety; toxicity; virolgical failure; Cohort Studies; Female; Heterocyclic Compounds 3-Ring; Humans; Middle Aged; Oxazines; Piperazines; Prospective Studies; Pyridones; Anti-HIV Agents; HIV InfectionssafetyPediatricsmedicine.medical_specialtySettore MED/17 - Malattie InfettivePyridonesAnti-HIV AgentsOxazineHuman immunodeficiency virus (HIV)adverse eventHIV Infectionsvirolgical failurePyridonemedicine.disease_cause3-RingHIV Infections.PiperazinesCohort Studieschemistry.chemical_compoundHeterocyclic CompoundsHIV; adverse events; dolutegravir; durability; safety; toxicity; virolgical failureOxazinesAntiretroviral treatmentMedicineHumansProspective StudiesAdverse effectPiperazinebusiness.industryPublic Health Environmental and Occupational HealthHIVtoxicityAnti-HIV AgentMiddle Agedadverse eventsDiscontinuationdolutegravirvirolgical failure.Prospective StudieInfectious DiseaseschemistryDolutegravirdurabilityObservational studyFemaleCohort StudiebusinessHeterocyclic Compounds 3-RingHuman
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Estimation of durability of new surface courses using accelerated load test and expert's opinions

2022

There is an increasing interest among road authorities in studying sustainability assessment of road infrastructure. The durability of the surface course is a critical factor in these calculations and must be carefully considered in the analysis. New types of asphalt mixes with the potential to improve the results in the sustainability assessment have no proven track record and are thus more likely not to be used until solid performance data is available. To bridge the gap and diminish the uncertainty about the durability of Green asphalt mixes for surface courses, a combination of laboratory tests and tests in a circular road simulator were performed. Eight mixes were tested in total, four…

asphaltSustainabilitydurabilityservice life
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Hydrolytic degradation of PLA/Posidonia Oceanica green composites: A simple model based on starting morpho-chemical properties

2021

Abstract In this work, we studied the degradability of PLA-based biocomposites containing Posidonia Oceanica flour at different loading levels and aspect ratios. Hydrolytic tests were carried out in neutral (pH = 7.4) and alkaline (pH = 10) environment. Time-dependent evolution of some key features, including residual mass and solution uptake, was monitored, and correlated with the changes observed in both morphology and chemical structure of the matrix. The results pointed out that biocomposites degraded much faster than neat PLA in both conditions, up to lose 70% of their initial weight after 1000 h immersion. A complex mechanism was unveiled, evidencing the crucial role of the fillers, c…

chemistry.chemical_classificationBio composites Durability Environmental degradation Hydrolytic degradation Natural fibre compositesMorphology (linguistics)Materials sciencebiologyChemical structureGeneral Engineering02 engineering and technologyPolymer010402 general chemistry021001 nanoscience & nanotechnologybiology.organism_classification01 natural sciences0104 chemical sciencesMatrix (chemical analysis)HydrolysisSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistryPosidonia oceanicaCeramics and CompositesDegradation (geology)Chemical stabilityComposite material0210 nano-technology
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Closed-loop recycling. A case study of films for greenhouses

2010

Abstract The degradation undergone by plastic films used for greenhouse coverage is the main cause of the worsening of the processability, of the mechanical properties and of the durability of secondary materials obtained by their recycling. This means that this secondary material cannot be processed to produce films for the same applications (closed-loop recycling). In this work different strategies are proposed to improve the processability, some mechanical properties and the resistance to photo-oxidation of these secondary materials. In particular, homopolymer blends or multilayer films where the secondary material is used in combination with virgin polymer give the best results.

chemistry.chemical_classificationMaterials sciencePolymers and PlasticsPlastic filmGreenhousePolymerCondensed Matter PhysicsDurabilitychemistryMechanics of MaterialsMaterials ChemistryDegradation (geology)ExtrusionPolymer blendComposite materialClosed loopPolymer Degradation and Stability
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Atmospheric aging and surface degradation in As2S3 fibers in relation with suspended-core profile

2015

Abstract Microstructured optical fibers (MOF) can be seen as next generation fiber of significance in advancing the compact optics because of its excellent compatibility in integrated optics. However, the degradation of their physicochemical properties limits their efficiency and lifetime. Atmospheric moisture is responsible for the degradation of amorphous systems especially chalcogenide glasses. In the light of previously reported studies, in order to clarify the aging process continuously evolving in sulfide microstructured optical fiber over time, a detailed investigation of this phenomenon has been conducted. The time-dependent transmission and glass chemical deterioration have been st…

chemistry.chemical_classificationOptical fiberMaterials scienceAtmospheric moistureSulfideChalcogenideOrganic ChemistryChalcogenide glassMicrostructured optical fiberDurabilityAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic Materialslaw.inventionAmorphous solidInorganic Chemistrychemistry.chemical_compoundchemistrylawElectrical and Electronic EngineeringPhysical and Theoretical ChemistryComposite materialSpectroscopyOptical Materials
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Anti-/Pro-Oxidant Behavior of Naturally Occurring Molecules in Polymers and Biopolymers: A Brief Review

2019

Polymers and biopolymers are continuously subjected to the action of different stress factors, such as oxygen, heat, UV light, mechanical stress, humidity, etc., during their processing and service life, undergoing overall oxidative degradation, that causes performance and property deterioration. To improve the resistance at high temperatures and long-term weatherability of the polymers and biopolymers, usually, during their manufacturing, synthetic antioxidants and UV-light stabilizers are added. In the past decade, several concerns related to the impact of the synthetic stabilizers have emerged, and to reduce their negative effect on human health and the environment, their replacement wit…

chemistry.chemical_classificationOxidative degradationRenewable Energy Sustainability and the EnvironmentChemistryGeneral Chemical Engineering02 engineering and technologyGeneral ChemistryPolymerSettore CHIM/06 - Chimica OrganicaPolyphenols Vitamins Carotenoids Oxidative degradation Polymer and biopolymer protection Melt stabilization Durability Pro-oxidant activity010402 general chemistry021001 nanoscience & nanotechnologyPro-oxidant01 natural sciences0104 chemical sciencesHuman healthSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiChemical engineeringEnvironmental ChemistryMolecule0210 nano-technology
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Complex composite structures with integrated piezoelectric transducers

2016

International audience; Nowadays, in different industrial fields as transport or aerospace, a research effort is conducted to reduce the structural weight. One of the most promising solutions is the use of composite structures due to their high stiffness, their low mass density and their low damping factor. At the same time, there is an intensification of the operational dynamic environment and an increase of durability requirements. These different expectations seem to be contradictory. One solution to manage these points is to design and manufacture smart composite structures with a fully distributed set of integrated piezoelec-tric transducers. These structures are able to modify their m…

composite structureComputer scienceComposite numberComputational MechanicsMechanical engineering[SPI.MECA.MSMECA]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Materials and structures in mechanics [physics.class-ph]02 engineering and technology01 natural sciences[SPI]Engineering Sciences [physics]Active vibration control0103 physical sciencesAerospace[PHYS.MECA.VIBR]Physics [physics]/Mechanics [physics]/Vibrations [physics.class-ph]010302 applied physicsbusiness.industryApplied Mathematicstransducers integration[PHYS.MECA]Physics [physics]/Mechanics [physics]material characterizationMechatronics021001 nanoscience & nanotechnologyPiezoelectricityDurabilityComputer Science ApplicationsComputational Mathematicscomplex structureModeling and SimulationDamping factorPMUT[PHYS.MECA] Physics [physics]/Mechanics [physics]0210 nano-technologybusiness
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The Durability of Composite Wood-Steel Systems

2010

Nell’ambito della valutazione e del controllo della qualità tecnologica in edilizia, la conoscenza del comportamento nel tempo dei prodotti e componenti complessi per l’edilizia, risulta aspetto fondamentale, in particolare per quei prodotti tecnologicamente “innovativi” per i quali la normativa non prevede ancora prove specifiche per valutarne la durabilità. In particolare, oggi risulta sempre più diffuso l’impiego di sistemi assemblati o con connessioni tra materiali di diversa natura, tra cui i sistemi legno-acciaio, ottenuti rinforzando le travi in legno lamellare con piastre in acciaio forate, incollati mediante una resina epossidica bicomponente. Tali sistemi, che sono stati già ogget…

composite systems bond characteristics wood-epoxy-steel interfaces accelerated aging durability.Settore ICAR/11 - Produzione Edilizia
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Durability of Advanced Polymer Composites: Book of abstracts

2021

durability:NATURAL SCIENCES::Physics [Research Subject Categories]compositespolymers
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Calcestruzzi rinforzati con fibre di PET. Sperimentazioni sull'impiego delle fibre di PET provenienti dalla raccolta differenziata nella produzione d…

2013

La sperimentazione esposta tratta dell’impiego di fibre di PET, ricavate dal semplice taglio di contenitori per bevande, nel rinforzo di calcestruzzi destinati anche a impieghi strutturali. Indaga la durabilità delle fibre in ambiente fortemente basico e le caratteristiche meccaniche di calcestruzzi rinforzati con differenti dosaggi di fibre. Le osservazioni al microscopio elettronico a scansione (SEM) di fibre di PET immerse per 13 giorni a 65°C in acqua distillata e in due soluzioni fortemente basiche mostrano la buona durabilità delle fibre in soluzione 0,103 M di NaOH, che simula la basicità della soluzione acquosa che permea la matrice cementizia. L’influenza delle fibre e del loro dos…

durabilitàcaratteristiche meccanichesostenibilità calcestruzzi speciali FRC fibre di PETFiber-reinforced concretePET bottleAlkali resistanceSettore ICAR/10 - Architettura TecnicaSettore ICAR/11 - Produzione Ediliziamechanical propertiesPET fiberDurability
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