Search results for "Dynamics"

showing 10 items of 9782 documents

Significance of hyperlactatemia in acute hypnotic drug poisoning

1981

Lactate concentration, fibrinogen and fibrin(ogen) -- degradation-products in central venous blood were analysed in 35 unconscious patient with acute hypnotic drug poisoning (HDP) and compared with the results in 13 healthy control persons undergoing the same degree of forced diuresis via central venous catheters. Blood samples were taken on admission and at 12 h intervals up to 36 h after admission. Patients with HDP were attributed to the categories of moderate intoxications (n = 17) and severe intoxications (n = 18) according to their clinical condition. On admission, blood lactate was significantly higher in severe intoxication (3.90 +/- 2.94 mmol/l) as compared to the control group (1.…

AdultMaleUnconsciousnessFibrinogenFibrinFibrin Fibrinogen Degradation ProductsDrug DiscoverymedicineBlood lactateHumansHypnotics and SedativesIn patientGenetics (clinical)biologybusiness.industryUnconsciousnessHemodynamicsFibrinogenGeneral MedicineVenous bloodHypnotic drugAnesthesiaLactatesbiology.proteinMolecular MedicineFemaleHyperlactatemiamedicine.symptombusinessmedicine.drugKlinische Wochenschrift
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Exploratory Factor Analysis and Validation Study of the Lifetime Severity Index for Cocaine, Spanish Version (LSI-C-Spanish)

2007

The purpose of the study was to do an exploratory factor analysis and to examine the criterion-related and discriminant validity of the Lifetime Severity Index for Cocaine (LSI-C), Spanish version. A sample of 171 outpatients from 10 drug centers in Spain participated in the study. We conducted the factor analysis with orthogonal rotation and examined correlations between the LSI-C total score and criterion variables as well as the score obtained by a quality of life measure. The factor analysis revealed 2 principal factors that explain 65.8% of the variance. Lower LSI-C scores were associated with taking medication, receiving social help, using cocaine fewer than 30 times during the previo…

AdultMaleValidation studymedicine.medical_specialtyIndex (economics)AdolescentPsychometricsPsychometricsPopulation DynamicsSeverity of Illness IndexCocaine-Related DisordersQuality of lifeSeverity of illnessmedicineHumansPsychiatryLanguagePsychiatric Status Rating ScalesDiscriminant validityReproducibility of ResultsSpanish versionMiddle AgedExploratory factor analysisHospitalizationPsychiatry and Mental healthSpainQuality of LifeFemaleSubstance Abuse Treatment CentersDrug OverdoseFactor Analysis StatisticalPsychologyDemographyJournal of Nervous & Mental Disease
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Effects on Heat Stress of a Flame-Retardant Ensemble for Aluminum Smelters

2000

A common belief is that a flame-retardant clothing ensemble will increase the level of heat stress over ordinary cotton work clothes. This is supported by bench tests on fabrics that indicate higher insulation and vapor resistance values for flame-retardant clothing. This research compared a flame-retardant clothing ensemble for an aluminum smelter (Zirpo wool shirt and FR8 denim pants) with typical cotton work clothing. Four young men walked on a treadmill at two work levels inside a climatic chamber under controlled conditions of heat stress. During each test, heart rate, core temperature, and skin temperatures were continuously monitored and recorded every 5 min. After a physiological st…

AdultMaleWork (thermodynamics)Threshold limit valuebusiness.industryWet-bulb globe temperatureEnvironmental engineeringPublic Health Environmental and Occupational HealthHumidityHeat Stress DisordersAtmospheric sciencesClothingStress (mechanics)Protective ClothingInflection pointOccupational ExposureMetallurgyHumansEnvironmental scienceRelative humidityThreshold Limit ValuesbusinessAluminumFlame RetardantsAIHAJ
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The enantiomers of phenprocoumon: pharmacodynamic and pharmacokinetic studies.

1976

The pharmacodynamics and pharmacokinetics of the optical enantiomers of phenprocoumon were studied in 5 normal subjects and compared to the racemic mixture. Each subject received a single oral dose of 0.6 mg/kg of racemic, S(-), and R(+) phenprocoumon. S(-) phenprocoumon was 1.6 to 2.6 times as a potent as R(+) phenprocoumon when the area under the effect/time curve was used to quantify the total anticoagulant effect per dose. Comparing the plasma concentrations that elicited the same anticoagulant effect, S(-) phenprocoumon was 1.5 to 2.5 times as potent as R(+) phenprocoumon. The anticoagulant activity of the racemic mixture was between that of the enantiomers. There was no distinct diffe…

AdultMalemedicine.drug_classMetabolic Clearance RateIn Vitro TechniquesPhenprocoumonStructure-Activity RelationshipPharmacokineticsCoumarinsmedicineHumansPharmacology (medical)Serum AlbuminPharmacologyVolume of distributionChromatographyChemistryAnticoagulantAnticoagulantsStereoisomerismHuman serum albuminKineticsPharmacodynamicsPhenprocoumonProthrombin TimeRacemic mixtureEnantiomermedicine.drugProtein BindingClinical pharmacology and therapeutics
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Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…

1992

In a previous paper, in which the experimental conditions of the present research are fully described (Parrot et al., this issue), heart rate (HR) was studied in 60 male and in 60 female subjects in response to a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), and an intermittent pink noise (R), all noises being emitted at the same LAeq = 75 dB for 15 min. Digital pulse level (PL) responses were concomitantly surveyed by the use of pulse oximetry, allowing continuous arterial oxygen saturation (SaO2) readings. An index of pulse reactivity (PRI) could be calculated. Arterial blood pressure was measured 7 times from the beginning to the end of each trial. At rest, within…

AdultMalemedicine.medical_specialtyAdolescentHemodynamicsBlood PressureAudiologyAnxietyPink noiseImpulse noiseHeart RateOccupational ExposureHeart rateAdaptation PsychologicalmedicineHumansHabituation Psychophysiologicmedicine.diagnostic_testbusiness.industryPulse (signal processing)Public Health Environmental and Occupational HealthHemodynamicsMiddle AgedSurgeryOccupational DiseasesPlethysmographyNoisePulse oximetryBlood pressureNoise TransportationNoise OccupationalFemaleVascular ResistancebusinessArousalInternational archives of occupational and environmental health
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Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…

1992

This study aimed at comparing for their cardiovascular effects: a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), an intermittent pink noise (R). All noises were presented at the same LAeq = 75 dB for 15 min each. Some 120 subjects were divided into 8 subgroups of 15 subjects each: OM (men between 40 and 50 years of age), OF (women, same age range), YM (men, between 15 and 20 years of age), YF (women, same age range), AM (typically anxious men, 20–25 years of age), AF (typically anxious women, same age range), NM (typicall anxiety-free men, same age range), and NF (typically anxiety-free women, same age range). Heart rate (HR), digital pulse level, and arterial blood p…

AdultMalemedicine.medical_specialtyAdolescentIndividualityBlood PressureAudiologyAnxietyPink noiseImpulse noiseSex FactorsHeart RateHeart rateAdaptation PsychologicalMedicineHumansRoad trafficPulse noisebusiness.industryPublic Health Environmental and Occupational HealthAge FactorsHemodynamicsMiddle AgedOccupational DiseasesNoiseBlood pressureNoise TransportationNoise OccupationalAnxietyFemaleVascular Resistancemedicine.symptombusinessArousalInternational archives of occupational and environmental health
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Mental representation of arm motion dynamics in children and adolescents.

2013

International audience; Motor imagery, i.e., a mental state during which an individual internally represents an action without any overt motor output, is a potential tool to investigate action representation during development. Here, we took advantage of the inertial anisotropy phenomenon to investigate whether children can generate accurate motor predictions for movements with varying dynamics. Children (9 and 11 years), adolescents (14 years) and young adults (21 years) carried-out actual and mental arm movements in two different directions in the horizontal plane: rightwards (low inertia) and leftwards (high inertia). We recorded and compared actual and mental movement times. We found th…

AdultMalemedicine.medical_specialtyAdolescentMovementlcsh:MedicineBiology050105 experimental psychologyYoung Adult03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationMotor imageryTask Performance and AnalysismedicineHumans0501 psychology and cognitive sciencesChildlcsh:ScienceMultidisciplinaryMotion dynamicsMovement (music)lcsh:R05 social sciencesAge FactorsParietal lobeMental state[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]ArmImaginationMental representationFemalelcsh:Q[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]030217 neurology & neurosurgeryResearch Article
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The spectrum of circadian blood pressure changes in type I diabetic patients.

2001

Background The objective of the present study was to characterize the spectrum of circadian blood pressure changes in type I diabetes at different stages of nephropathy by using two monitorings in each patient in order to avoid intra-individual variability. Patients and methods A total of 80 type I diabetic subjects and the same number of age, sex and awake mean blood pressure (BP)-matched controls were included. According to urinary albumin excretion, there were 57 normoalbuminurics, 15 persistent microalbuminurics and eight proteinurics. Two 24 h ambulatory blood pressure monitorings were performed at the same urinary albumin excretion stage in absence of antihypertensive treatment for ea…

AdultMalemedicine.medical_specialtyAmbulatory blood pressureAdolescentPhysiologyDiastoleHemodynamicsBlood PressureReference ValuesInternal medicineDiabetes mellitusHeart rateInternal MedicinemedicineAlbuminuriaHumansDiabetic NephropathiesCircadian rhythmbusiness.industryReproducibility of ResultsBlood Pressure Monitoring Ambulatorymedicine.diseaseCircadian RhythmProteinuriaEndocrinologyBlood pressureMean blood pressureDiabetes Mellitus Type 1CardiologyFemaleCardiology and Cardiovascular MedicinebusinessJournal of hypertension
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Metabolic and psychosocial effects of minimal invasive gastric banding for morbid obesity

2003

Obesity is considered a primary risk factor for cardiovascular disease and related mortality. The current study aimed to investigate the efficacy of minimal invasive gastric banding (GB) surgery for reducing caloric intake in morbid obesity, and to analyze the effects of weight loss on body composition and metabolic and psychosocial outcomes. Twenty-six adult severely obese patients (mean body mass index [BMI], 48.1 kg/m(2); range, 42 to 56) underwent adjustable silicone laparoscopic GB. Nine additional obese patients who declined surgery were treated with metformin (2 g daily) and served as a small additional group (BMI, 50.5 kg/m(2); range, 41 to 68). Presurgery and 17 +/- 2.2 months post…

AdultMalemedicine.medical_specialtyAnemiaEndocrinology Diabetes and MetabolismBody waterImpaired glucose toleranceEndocrinologyWeight lossInternal medicineActivities of Daily LivingWeight LossmedicineHumansHypoglycemic AgentsMinimally Invasive Surgical ProceduresDigestive System Surgical ProceduresTriglyceridesAnthropometrybusiness.industryStomachMetabolic disorderHemodynamicsmedicine.diseaseObesityMetforminObesity MorbidCholesterolEndocrinologyBody CompositionQuality of LifeLean body massFemaleLaparoscopymedicine.symptombusinessBody mass indexMetabolism
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Two-stage multi-Gaussian fitting of conduit artery photoplethysmography waveform during induced unilateral hemodynamic events.

2014

Photoplethysmography (PPG) is an optical technique with high diagnostic potential, yet clinical applications remain underdeveloped. Standardization of signal recording and quantification of waveform are essential prerequisites for broader clinical use. The aim of this study was to utilize a two-stage multi-Gaussian fitting technique in order to examine the parameters of conduit artery PPG waveform recorded during increasing the unilateral regional vascular resistance (RVR). This study was conducted on 14 young and healthy volunteers; various external compressions (ECs) were performed by inflating a tight cuff at 0, 40, 80, and 200 mmHg, while registering femoral PPG (wavelength 880 nm), dia…

AdultMalemedicine.medical_specialtyBiomedical EngineeringNormal DistributionHemodynamicsBiomaterialsInternal medicinePhotoplethysmogrammedicineHumansPhotoplethysmographyReactive hyperemiaHemodynamicsBlood flowArteriesmedicine.diseaseArterial occlusionAtomic and Molecular Physics and OpticsHealthy VolunteersElectronic Optical and Magnetic MaterialsFemoral Arterymedicine.anatomical_structureBlood pressureAnesthesiaCardiologyVascular resistanceArterial stiffnessFemaleVascular ResistanceJournal of biomedical optics
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