Search results for "Dynamics"

Regional Economic Integration in the Southern African Development Community (SADC): Analysing the Dynamics and Performance

2020

This article analyses the dynamics and performance of regional economic integration in the Southern African Development Community (SADC). It proposes an innovative theoretical approach to the analysis of regionalism that refers to cooperation theory and takes the impact of external actors explicitly into account. The motivation for this research stems from the observation of a new wave of regionalism in the Global South. Many of these new or reformed regional integration organisations (RIOs) comprise of developing countries, particularly in Africa. In contrast to expectations of most mainstream integration theories, new regionalisms in the Southern Hemisphere have come into existence and sh…

Rotational effects on the oscillation frequencies of newly born proto-neutron stars

2003

In this paper we study the effects of rotation on the frequencies of the quasi-normal modes of a proto-neutron star (PNS) born in a gravitational collapse during the first minute of life. Our analysis starts a few tenths of seconds after the PNS formation, when the stellar evolution can be described by a sequence of equilibrium configurations. We use the evolutionary models developed by Pons et al. (1999; 2001) that describe how a non rotating star cools down and contracts while neutrino diffusion and thermalization processes dominate the stellar dynamics. For assigned values of the evolution time, we set the star into slow rotation and integrate the equations of stellar perturbations in th…

Photocycle of point defects in highly- and weakly-germanium doped silica revealed by transient absorption measurements with femtosecond tunable pump.

2022

AbstractWe report pump-probe transient absorption measurements addressing the photocycle of the Germanium lone pair center (GLPC) point defect with an unprecedented time resolution. The GLPC is a model point defect with a simple and well-understood electronic structure, highly relevant for several applications. Therefore, a full explanation of its photocycle is fundamental to understand the relaxation mechanisms of such molecular-like systems in solid state. The experiment, carried out exciting the sample resonantly with the ultraviolet (UV) GLPC absorption band peaked at 5.1 eV, gave us the possibility to follow the defect excitation-relaxation dynamics from the femto-picosecond to the nan…

Medium-term effects of bisoprolol administration on renal hemodynamics and function in mild to moderate essential hypertension

2007

Arterial hypertension is a significant cause of end-stage renal failure; effective treatment of hypertensive patients reduces the rate of progression of this disorder. ss-Blockers, particularly nonselective agents, are associated with deterioration of renal function in patients with chronic renal failure. Previous studies on the interaction of the beta1-selective adrenergic antagonist bisoprolol with kidney function have been performed only acutely and over the short term. This study was designed to evaluate the antihypertensive efficacy and effects on renal hemodynamics and function of bisoprolol during medium-term (6 mo) treatment of patients with mild to moderate essential hypertension. …

PUBLIC POLICY PLANNING TO ENHANCE THE RESILIENCE OF SOCIO-ECOLOGICAL SYSTEMS TO CLIMATE CHANGE: OPERATIONALIZING RESILIENCE CONCEPTS FROM A DYNAMIC P…

This study outlines a system dynamic based approach to the planning for resilience in food systems to climate change. The processes described and the insights gained are novel in the literature since they focus on describing operational aspects of resilience that can be generalized to multiple contexts and problems. On the one hand, the process described offers an aid for researchers and practitioners operationalizing resilience in public sector settings. Simultaneously, the insights gained from multiple stakeholder discussions and modelling work open new questions regarding the general mechanisms driving resilience in food systems. Climate change is threatening the extent to which social, …

The Retirement and Early Retirement in Italy: a System Dynamics approach

2006

The main aim of this study is underline that System Dynamics approach allows the building of a general framework in which psychological, economic, social, legal and organizational variables converge to describe the retirement behaviour and its main unintended consequences. It’s emphasized that organizational commitment and psychological contract breach play a considerable role in the dynamics of retirement behaviour. In the first part of this paper, an analysis of main contributions in the retirement and early retirement fields is outlined. Further, the psychological, social, economical and legal approach to retirement behaviour is also briefly remarked. In the second part, retirement pheno…

Reverse Screening on Indicaxanthin from Opuntia ficus-indica as natural chemoactive and chemopreventive agent

2018

Indicaxanthin is a bioactive and bioavailable betalain pigment extracted from Opuntia ficus indica fruits. Indicaxanthin has pharmacokinetics proprieties, rarely found in other phytochemicals, and it has been demonstrated that it provides a broad-spectrum of pharmaceutical activity, exerting antiproliferative, anti-inflammatory and neuromodulator effects. The discovery of the Indicaxanthin physiological targets plays an important role in understanding the biochemical mechanism. In this study, combined reverse pharmacophore mapping, reverse docking, and text-based database search identified Inositol Trisphosphate 3-Kinase (ITP3K-A), Glutamate carboxypeptidase II (GCPII), Leukotriene-A4 hydro…

Does Intraspecific Variation in rDNA Copy Number Affect Analysis of Microbial Communities?

2021

Amplicon sequencing of partial regions of the ribosomal RNA loci (rDNA) is widely used to profile microbial communities. However, the rDNA is dynamic and can exhibit substantial interspecific and intraspecific variation in copy number in prokaryotes and, especially, in microbial eukaryotes. As change in rDNA copy number is a common response to environmental change, rDNA copy number is not necessarily a property of a species. Variation in rDNA copy number, especially the capacity for large intraspecific changes driven by external cues, complicates analyses of rDNA amplicon sequence data. We highlight the need to (i) interpret amplicon sequence data in light of possible interspecific and intr…

Laboratory Measurements of Upstream Overdeepening

2000

MbCo in Saccharide Solid Amorphous Systems: A Combined FTIR and SAXS Study

2011

Saccharides, and in particular trehalose, are known for their efficiency in protecting biostructures against environmental stress [1], although the preservation mechanism is still debated. Experiments and simulations [2,3] on carboxy-myoglobin (MbCO) showed that the protein dynamics is highly inhibited in dry trehalose matrices, the inhibition being dependent on the water content. In these conditions, a mutual protein-matrix structural and dynamic influence is observed.Here we report a combined FTIR and SAXS study on MbCO embedded in dry amorphous matrices of trehalose and sucrose. FTIR measurements were performed at different protein/sugar ratios, focussing on the stretching band of the bo…