Search results for "E.P.S."

A Hierarchical Detection and Response System to Enhance Security Against Lethal Cyber-Attacks in UAV Networks

2018

International audience; Unmanned aerial vehicles (UAVs) networks have not yet received considerable research attention. Specifically, security issues are a major concern because such networks, which carry vital information, are prone to various attacks. In this paper, we design and implement a novel intrusion detection and response scheme, which operates at the UAV and ground station levels, to detect malicious anomalies that threaten the network. In this scheme, a set of detection and response techniques are proposed to monitor the UAV behaviors and categorize them into the appropriate list (normal, abnormal, suspect, and malicious) according to the detected cyber-attack. We focus on the m…

Assessing drought vulnerability and adaptation among farmers in Gadaref region, Eastern Sudan

2018

Agricultural productivity in rural areas is severely affected by climate variability, and this elevates the vulnerability of rural households to food insecurity. This study examines the socio-economic vulnerability of farmers who are susceptible to droughts in the five agricultural-based regions of Gadaref, Eastern Sudan. A survey was carried out in 500 households to collect data on socio-economic and livelihood indicators. The data analyzed from these indicators were used to generate the three components of drought vulnerability: exposure, sensitivity and adaptive capacity. The analysis revealed that the regions deemed to be most vulnerable to both drought and climate variability were also…

The learning curve, accuracy, and interobserver agreement of endoscope-based confocal laser endomicroscopy for the differentiation of colorectal lesi…

2012

Background: The endoscope-based confocal laser endomicroscopy (eCLE) system allows in vivo imaging of colorectal epithelium. Little is known about the learning curve for accurate interpretation of confocal images acquired with eCLE. Objective: To determine the learning curve of eCLE, its diagnostic accuracy, and the intra- and interobserver agreement for the differentiation of colorectal lesions. Design: Post hoc assessment of selected eCLE images. Setting: Academic centers. Patients: This study involved colonoscopic images from 47 patients. Main Outcome Measurements: Learning curve of eCLE, accuracy, and intraobserver and interobserver agreement. Methods: Three endoscopists received a shor…

The Effect of Natural Allergen Exposure on the Maximal Response Plateau to Adenosine 5′-monophosphate and on Exhaled Nitric Oxide of Alveolar and Bro…

2010

Effects of gait speed on stability of walking revealed by simulated response to tripping perturbation

2013

The objective of this work was to study stability of walking over a range of gait speeds by means of muscle-driven simulations. Fast walking has previously been related to high likelihood of falling due to tripping. Various measures of stability have shown different relationships between walking speed and stability. These measures may not be associated with tripping, so it is unclear whether the increase in likelihood of falling is explicable by an increase in instability. Here, stability with respect to a constant tripping perturbation was quantified as the immediate passive response of torso to the perturbation. Subject-specific muscle-driven simulations of eight young healthy subjects wa…

Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination▿ †

2008

ABSTRACTCytomegalovirus (CMV) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitution of protective antiviral immunity mediated primarily by CD8 T cells. Furthermore, adoptive transfer of CMV-specific memory CD8 T (CD8-TM) cells is a therapeutic option for preventing CMV disease in HSCT recipients. Given the different CMV infection histories of donor and recipient, a problem may arise from an antigenic mismatch between the CMV variant that has primed donor immunity and the CMV variant acquired by the recipient. Here, we have used the BALB/c mouse…

Highly protective in vivo function of cytomegalovirus IE1 epitope-specific memory CD8 T cells purified by T-cell receptor-based cell sorting.

2005

ABSTRACTReconstitution of antiviral CD8 T cells is essential for controlling cytomegalovirus (CMV) infection after bone marrow transplantation. Accordingly, polyclonal CD8 T cells derived from BALB/c mice infected with murine CMV protect immunocompromised adoptive transfer recipients against CMV disease. The protective population comprises CD8 T cells with T-cell receptors (TCRs) specific for defined and for as-yet-unknown viral epitopes, as well as a majority of nonprotective cells with unrelated specificities. Defined epitopes include IE1/m123 and m164, which are immunodominant in terms of the magnitude of the CD8 T-cell response, and a panel of subordinate epitopes (m04, m18, M45, M83, a…

Lymphoma cell apoptosis in the liver induced by distant murine cytomegalovirus infection.

2006

ABSTRACTCytomegalovirus (CMV) poses a threat to the therapy of hematopoietic malignancies by hematopoietic stem cell transplantation, but efficient reconstitution of antiviral immunity prevents CMV organ disease. Tumor relapse originating from a minimal residual leukemia poses another threat. Although a combination of risk factors was supposed to enhance the incidence and severity of transplantation-associated disease, a murine model of a liver-adapted B-cell lymphoma has previously shown a survival benefit and tumor growth inhibition by nonlethal subcutaneous infection with murine CMV. Here we have investigated the underlying antitumoral mechanism. Virus replication proved to be required, …

Natural and adoptive T-cell immunity against herpes family viruses after allogeneic hematopoietic stem cell transplantation.

2011

Reactivated infections with herpes family-related cytomegalovirus, Epstein–Barr virus and varicella zoster virus are serious and sometimes life-threatening complications for patients undergoing allogeneic hematopoietic stem cell transplantation. The pathogenesis of these infections critically involves the slow and inefficient recovery of antiviral T-cell immunity after transplantation. Although efficient drugs to decrease viral load during this vulnerable period have been developed, long-term control of herpes viruses and protection from associated diseases require the sufficient reconstitution of virus-specific memory T cells. To heal the deficiency by immunotherapeutic means, numerous re…

Body composition and nutrition of female athletes

2019

Background. The somatic features of the athletes’ bodies partially determine their sporting level and are conditioned to a large extent by the state of nutrition. Objective. The aim of this paper is to present nutritional status and its correlation with the somatic determinants of training athletes and physical education students. Material and methods. This study involved 12 weightlifting players (subgroup-WL), 15 soccer players (subgroup-SP), 12 table tennis players (subgroup-TT) and 12 female students of physical education (subgroup-C). In all subjects, the age and somatic variables were recorded and the daily intake of energy, water, proteins, fats and carbohydrates was determined by 24-…