Search results for "E7"
showing 10 items of 152 documents
Cazuma 1, nueva localidad de micromamíferos (Mammalia, Rodentia) del Aragoniense superior en la cuenca de Quesa - Bicorp (prov. Valencia)
2021
En el presente trabajo se describe la asociación de Megacricetodon crusafonti (Freudenthal, 1963), Megacricetodon sp. y Heteroxerus aff. grivensis (Forsyth Major, 1893) de Cazuma 1, localidad situada en el sector de Bicorp, en la cuenca terciaria de Quesa - Bicorp (Prov. Valencia). La edad atribuida a esta localidad es Aragoniense Superior. Hasta el momento, con ésta, ya son cinco las localidades conocidas de mamíferos en el Aragoniense de la cuenca de Quesa - Bicorp (Cazuma 1, Quesa 0, Quesa 2, Quesa 3 y Quesa 6).
Fosildiagénesis del anélido Rotularia spirulaea (Lamarck, 1818) (Polychaeta, Serpulidae) en el Eoceno del dominio pirenaico occidental
2018
The presence of the fossil polychaete Rotularia spirulaea (Lamarck, 1818) in Eocene deposits (middle Lutecian – upper Bartonian and (?) Priabonian) belonging to the western Pyrenean Domain is verified. In this paper, a fossildiagenetic study has been carried out. Fossils from three areas, corresponding to diff erent depositional settings, have been analysed. In area 1, sediments of the Ardanatz Sandstone and Ilundain Marls formations [Pamplona Basin and adjoining areas (Navarre)], were sampled. Here, the specimens of R. spirulaea were not substantially affected by taphonomic reworking and the original microstructure of the carbonate tube is preserved. The test consists of a thick external …
El género Parabailiella Thoral, 1946 (Trilobita) en el Cámbrico Medio de las cadenas ibéricas (NE de España)
2021
Se analiza el registro del género Parabailiella Thoral, 1946 en el Cámbrico medio de las Cadenas Ibéricas, al tiempo que se identifican y describen por primera vez en la región las cuatro especies que previamente se habían incluido en este género. La mayoría de las especies se encuentran registradas en varias secciones y las cuatro se han identificado en la sección Jarque 1. La distribución bioestratigráfica del género abarca desde el Leoniense medio hasta la base del Caesaraugustiense superior, lo que equivale en la escala propuesta por la International Subcommission on Cambrian Stratigraphy (ISCS) a la mayor parte del Piso 5 del Cámbrico y a la parte inferior del Piso Drumiense. La distri…
Primer estudio experimental sobre los efectos de la digestión en restos esqueléticos de murciélagos (Mammalia: Chiroptera)
2018
Taphonomic studies dealing with small mammals do not usually consider bats. Therefore, the degree to which bat bones are modi? ed by predation and other taphonomic agents are largely unknown. Here we present the results obtained from a set of experiments developed to approach this issue, focusing initially on the e?ect of digestion. For this purpose several bat bones and teeth were exposed to HCl and to two di?erent proteolithic enzymes. The experiments showed that bat bones are altered by acidic and enzymatic attack in a similar way as the bones of other small mammals. However, some patterns were observed in the teeth that had not been previously described in other groups. Thus, both the i…
Bailiaspis (Trilobita) with English affinities from the Mansilla Formation (Cambrian Series 3 of the Iberian Chains; NE Spain)
2020
A new study of the trilobite record in the Mansilla Formation (Iberian Chains, NE Spain) has led to the discovery of the presence of Bailiaspis aff. tuberculata, B. cf. tuberculata and Bailiaspis sp., the first certain citation of this genus in the Mediterranean subprovince. The age of the findings extends from Eccaparadoxides asturianus Zone (upper Leonian) to the lowermost Badulesia tenera Zone (lower Caesaraugustan), which correspond to the upper part of Stage 5 of Cambrian Series 3 and, probably, the lowermost Drumian. The specimens show the cranidial anterior border expanding backwards, forming a plectrum that is characteristic of Bailiaspis. The main characters of the three taxa inclu…
Early Jurassic (Sinemurian) gastropods from the Lusitanian Basin (west of Portugal)
2020
The Sinemurian gastropod specimens herein studied come from two sources: from museum collections and from samplings in field. The study of the Sinemurian gastropod specimens housed in the collections of the Museu Geológico (Laboratório Nacional de Energia e Geologia), Museu Nacional de História Natural e da Ciência (University of Lisbon), Museu da Ciência (University of Coimbra) and of the Museu de História Natural e da Ciência (University of Porto), has allowed the systematic and taxonomical update of this material. These specimens come mostly from Sinemurian outcrops in S. Pedro de Moel area and Coimbra region, and were collected by Paul Choffat and collaborators in the geological field w…
Late Quaternary marine ostracods of the Basque Basin (S Bay of Biscay): taxonomy and distribution
2018
Late Quaternary taxonomy and ecologic and age distributions of ostracods from the Basque Basin (S Bay of Biscay) are described. More than forty-four thousands ostracod specimens have been obtained from one hundred surface samples and core samples from six cores located in shelf and upper bathyal depths and other infrabathyal core as comparative deep reference. A total of 155 species have been taxonomically described, belonging to 67 genera. Most characteristic species (123) have been SEM figured, and ecologic-geographic distributions and ages have been provided for all species. The resulting database will be a useful help for palaeoceanographic and palaeoclimatologic studies of the region.
Human Papillomavirus Type 16 E7 Peptide-Directed CD8+ T Cells from Patients with Cervical Cancer Are Cross-Reactive with the Coronavirus NS2 Protein
2003
ABSTRACTHuman papillomavirus type 16 (HPV16) E6 and E7 oncoproteins are required for cellular transformation and represent candidate targets for HPV-specific and major histocompatibility complex class I-restricted CD8+-T-cell responses in patients with cervical cancer. Recent evidence suggests that cross-reactivity represents the inherent nature of the T-cell repertoire. We identified HLA-A2 binding HPV16 E7 variant peptides from human, bacterial, or viral origin which are able to drive CD8+-T-cell responses directed against wild-type HPV16 E7 amino acid 11 to 19/20 (E711-19/20) epitope YMLDLQPET(T) in vitro. CD8+T cells reacting to the HLA-A2-presented peptide from HPV16 E711-19(20)recogni…
Evaluation of HBs, HBc, and frCP virus-like particles for expression of human papillomavirus 16 E7 oncoprotein epitopes.
2002
<i>Objectives:</i> In an attempt to develop virus-like particles (VLPs) as experimental vaccine against human papilloma virus (HPV)-induced tumours, the HPV16 E7 oncoprotein epitopes spanning amino acid (aa) residues 35–98 were expressed on three proteins capable of VLP formation: hepatitis B virus (HBV) surface (HBs) and core (HBc) antigens, and RNA phage fr coats (frCP). <i>Methods:</i> The profile of immunoglobulin isotypes induced in Balb/C mice after immunization with purified chimeric proteins was studied. <i>Results:</i> The HBs*-E7(35–54) protein expressing E7 residues 35–54 between residues 139 and 142 of the HBs carrier formed HBs-like particles…
An Upper Mississippian echinoderm microfauna from the Genicera Formation of northern León (Carboniferous, Cantabrian Mountains, N Spain)
2020
For the first time an echinoderm microfauna is recorded from the cephalopod limestone facies (‘griotte facies’) of the lower Carboniferous (Mississippian) Genicera Fm. (Alba Fm.). The formation is widespread in the Cantabrian Mountains in NW Spain, but the ossicles are from some sections in the surroundings of the Bernesga valley in northern León. They have been derived from insoluble acetic acid residues from samples of the upper and especially of the uppermost part of the formation (Canalón Mb. and Millaró Beds). The microfauna include taxonomically treated wheel-shaped ossicles, sieve-plates and rods of holothurians, goniodonts of ophiocistioids, and ophiuroid and stenuroid skeletal elem…