Search results for "E7"
showing 10 items of 152 documents
Understanding Blood versus Blond Orange Consumption: A Cross-Cultural Study in Four Countries
2022
Understanding consumer perceptions and attitudes to specific fruit is key information for not only increasing fruit consumption, but also for marketing reasons. It may also give clues to breeders to set quality objectives. This study explores different aspects that help to explain blood vs. blond orange consumption: availability and consumption habit, satisfaction attributes, facilitators and consumption barriers, consumption contexts, expectations and purchase intention. The study was conducted in China, Mexico, Spain and Italy, where citrus fruit consumers were invited to respond an online questionnaire. Our results revealed Italy as the country with the highest availability and consumpti…
Architectural effects on fossil preservation. The case of macaroni coralline algae
2020
Coralline red algae with protuberances in their thalli are common and instructive examples of fabricational effects on fossil preservation. The body (thallus) of non-geniculate coralline algae is a coherent mass of cell filaments. All vegetative cells, except the epithallial ones at the tip of each filament are enclosed by a high-Mg calcite wall. Many extant and extinct species of coralline algae have protuberances in their thalli. Protuberances appear both on the dorsal surface of algae that grow attached to a rigid substrate and in unattached specimens living on loose sediment. In either case, protuberances develop due to a higher growth rate of fi laments in their centre. In each growth …
Naturally processed and HLA-B8-presented HPV16 E7 epitope recognized by T cells from patients with cervical cancer.
2004
Several major histocompatibility complex (MHC) alleles have been reported to present peptides derived from the HPV16 E7 oncoprotein to T cells. We describe an overrepresentation of the HLA-B8 allele (28.44%) in cervical cancer patients as compared to the MHC class I allele frequency in a local healthy control population (18.80%) and the identification of an HLA-B8-binding peptide TLHEYMLDL (HPV16 E77–15), which is able to drive HPV16 E7-specific and MHC class I-restricted T-cell responses in peripheral blood lymphocytes from healthy individuals. TLHEYMLDLspecific T cells recognize the naturally processed and presented peptide on HPV16 cervical cancer cells transfected with the HLA-B8 gene d…
Geographical distribution and oncogenic risk association of human papillomavirus type 58 E6 and E7 sequence variations.
2013
Human papillomavirus (HPV) 58 accounts for a notable proportion of cervical cancers in East Asia and parts of Latin America, but it is uncommon elsewhere. The reason for such ethnogeographical predilection is unknown. In our study, nucleotide sequences of E6 and E7 genes of 401 HPV58 isolates collected from 15 countries/cities across four continents were examined. Phylogenetic relationship, geographical distribution and risk association of nucleotide sequence variations were analyzed. We found that the E6 genes of HPV58 variants were more conserved than E7. Thus, E6 is a more appropriate target for type-specific detection, whereas E7 is more appropriate for strain differentiation. The frequ…
Witnesses of the early Pliocene sea-level rise in the Manilva Basin (Málaga, S Spain)
2020
The Sierra de la Utrera, a relief in the Manilva Basin (Malaga, SW Spain), shows bored surfaces at different heights above present-day sea level, from 96 m to 287 m. Borings occur in the eastern, central, and western parts of the Canuto de la Utrera, a prominent gorge in the central southern part of the relief excavated in Mesozoic limestones, as well as on the western end of the Canuto Chico, a smaller canyon in the northern part. Pliocene marine deposits fossilized the bored surfaces. Bored boulders of the substrate are embedded in the Pliocene sediments. The traces Gastrochaenolites ispp., Entobia ispp., Caulostrepsis ispp., Circolites kotoucensis, and Ericichnus asgaardi have been ident…
Late Carnian-Early Norian ammonoids from the GSSP candidate section Pizzo Mondello (Sicani mountain, Sicily).
2012
A small collection of ammonoids from the Upper Triassic Scillato Formation at Pizzo Mondello (Agrigento, Sicily) is studied. The specimens were collected in a framework of a project aimed at providing an integrated high-resolution bio-chronostratigraphic support to the Upper Carnian-Norian magnetostratigraphic scale defined at this site, that is located in an historical area from which G.G. Gemmellaro collected the Upper Triassic of ammonoids monographed at the beginning of the XX century. The specimens from Pizzo Mondello were bed-by-bed sampled and represent the first collection of Upper Triassic ammonoids described from Sicily since Gemmellaro time. Quite several levels of the Pizzo Mond…
Microstructure of Triassic conodont Pseudofurnishius murcianus van den Boogaard: Functional implications
2020
Pseudofurnishius murcianus van den Boogaard is a Triassic conodont with a very characteristic morphology, a blade with a rostral platform heavily denticulated, that makes it easily distinguishable from other coeval species. It is a well-know taxon that has been the object of several palaeobiological works, focused on their apparatus reconstruction, ontogeny and, recently, their P 1 element function. In order to increase our palaeobiology knowledge of this taxon we undertook a histological analysis to corroborate the functional hypothesis established for this conodont. The histological study demonstrated the presence of different microstructural types, suggesting that they are functional ada…
Taxonomic flux as a measure of evolutionary turnover
2021
We introduce a new metric, "taxonomic flux", to quantify evolutionary trends both within and across taxonomic boundaries. This metric is normalized, which reduces the effect of sample size disparity between biologic groups and time intervals. Furthermore, this methodology considers stratigraphic range data as a whole, and measures relative growth or decline of diversity values as they deviate from system stability. Such trends may yield key information relating to evolutionary processes and forcing functions, especially if these trends are correlative within particular taxa or niche occupancy. Thus far, scientists and researchers have been stymied by absolute values derived from unequal dat…
Developments and contributions in the study of La Rioja dinosaur footprints (Spain)
2020
In this paper the study of dinosaur tracks of La Rioja, which began in 1970, is presented as an example of knowledge development, achievements, and events occurring around a paleontological resource having strong media impact. Fieldwork, research, and dissemination since the publication of the first scientific works have been accompanied by activities to protect sites and consider them as natural and cultural heritage. Finally it is shown how a paleontological resource has also led to the development of the tourist infrastructure in the area
Fossil heritage conservation in Scotland
2019
A globally significant palaeontological resource is an integral part of Scotland’s geoheritage. A strong amateur collector tradition, extending back over two centuries has helped fuel scientific advance with the fossil resource also supporting hobby collecting. However, during the long history of collecting activity, finite fossil resources have been under pressure with instances of large-scale collecting that has damaged some particularly vulnerable localities. Legislative provisions over recent decades offer robust site-based protection that will have safeguarded some of the best and most representative fossil localities. Additionally, the Scottish Fossil Code, the first national code of …