Search results for "EB"
showing 10 items of 15658 documents
Esquema de derivación consistente de prioridades en un marco de consenso
2019
La toma de decisiones impregna la actividad humana. Con frecuencia, la decisión no es simple porque involucra elementos cualitativos, subjetivos, intangibles. En diversos métodos de decisión multi-criterio, los elementos protagonistas de tales procesos son comparados por pares, y tales comparaciones se utilizan para construir una matriz de comparaciones, de cuyo estudio emerge la decisión. En AHP (Analytic Hierarchy Process), por ejemplo, las prioridades se obtienen vía el vector propio de Perron de tales matrices. Para que la decisión sea adecuada, no obstante, las comparaciones deben ser aceptablemente consistentes. Pero cuando se comparan muchos elementos, la consistencia puede flaquear,…
Implicación de los receptores TLR4 en el daño cerebral causado por el consumo de alcohol
2012
El abuso de alcohol puede causar daño cerebral y en ciertos casos cursa con neurodegeneración, aunque los mecanismos moleculares de estos efectos se desconocen. El Sistema Nervioso Central (SNC) ha sido considerado, hasta muy recientemente, como un sistema inmunológicamente privilegiado (Galea et al., 2007). Sin embargo, estudios de los últimos años indican que el cerebro coordina y regula numerosos aspectos de la respuesta inmune innata, y que la inflamación representa un factor crítico y esencial para muchas enfermedades del SNC, como son las enfermedades neurodegenerativas (Wild et al., 2008). Igualmente, la respuesta del sistema inmune innato también desempeña un papel crucial en el dañ…
AML atbilstības novērtēšanai nepieciešamo datu pieprasīšana un apstrāde
2021
Kvalifikācijas darbā ir apkopota programmatūras prasību specifikācija, programmatūras projektējuma apraksts, testēšanas dokumentācija un projekta novērtējus SEB PFS sistēmas AML datu apmaiņas papildinājumi. Darba mērķis ir izstrādāt un sokumentēt sistēmas papildinājumus, kuri nodrošina automātisku AML datu apmaiņu fiziskām un juridiskām personām.
On the arithmetic and geometry of binary Hamiltonian forms
2011
Given an indefinite binary quaternionic Hermitian form $f$ with coefficients in a maximal order of a definite quaternion algebra over $\mathbb Q$, we give a precise asymptotic equivalent to the number of nonequivalent representations, satisfying some congruence properties, of the rational integers with absolute value at most $s$ by $f$, as $s$ tends to $+\infty$. We compute the volumes of hyperbolic 5-manifolds constructed by quaternions using Eisenstein series. In the Appendix, V. Emery computes these volumes using Prasad's general formula. We use hyperbolic geometry in dimension 5 to describe the reduction theory of both definite and indefinite binary quaternionic Hermitian forms.
Anorectal malformations and pregnancy-related disorders: a registry-based case-control study in 17 European regions
2013
Objective To identify pregnancy-related risk factors for different manifestations of congenital anorectal malformations (ARMs).Design A population-based case-control study.Setting Seventeen EUROCAT (European Surveillance of Congenital Anomalies) registries, 1980-2008.Population The study population consisted of 1417 cases with ARM, including 648 cases of isolated ARM, 601 cases of ARM with additional congenital anomalies, and 168 cases of ARM-VACTERL (vertebral, anal, cardiac, tracheo-esophageal, renal, and limb defects), along with 13371 controls with recognised syndromes or chromosomal abnormalities.Methods Multiple logistic regression analyses were used to calculate adjusted odds ratios …
Search for high energy cosmic muon neutrinos from variable gamma-ray sources and time calibration of the optical modules of the ANTARES telescope
2015
325 páginas. Tesis Doctoral del Departamento de Física Atómica, Molecular y Nuclear de la Universidad de Valencia y del Instituto de Física Corpuscular (IFIC).
Coronavirus Disease 2019–Associated Coagulopathy
2021
Patients with the severe form of coronavirus disease 2019 (COVID-19) have been frequently found to suffer from both arterial and venous thrombotic events due to the perpetuation of a hypercoagulable state. This phenomenon, termed COVID-19-associated coagulopathy (CC), is now considered a major component of the pathophysiology of this novel infectious disease, leading to widespread thrombosis. While at first, the vascular insults may be limited to the pulmonary microvasculature, as the disease progresses, systemic involvement occurs, culminating in distant organ thrombosis and multi-organ dysfunction syndrome. In this review article, we discuss recent insights into the pathophysiologic mecha…
An inhaled tumor necrosis factor-alpha-derived TIP peptide improves the pulmonary function in experimental lung injury: inhaled TIP peptide in experi…
2012
INTRODUCTION The lectin-like domain of TNF-α enhances the fluid clearance across the alveolar barrier. For experimental purposes, the lectin-like domain can be mimicked by a synthetic peptide representing the TIP-motif of TNF-α. The present study aims to assess the acute effect of TIP on the pulmonary function in a porcine model of acute respiratory distress syndrome (ARDS). METHODS Lung injury was induced in 16 pigs (25-27 kg) by bronchoalveolar lavage followed by injurious ventilation. Following randomisation, either nebulised TIP (1 mg/kg; AP301, APEPTICO, Vienna, Austria) or water for injection (control group) was administered. During 5 h of monitoring, the extravascular lung water inde…
Experimental lung injury induces cerebral cytokine mRNA production in pigs
2020
Background Acute respiratory distress syndrome (ARDS) is an important disease with a high incidence among patients admitted to intensive care units. Over the last decades, the survival of critically ill patients has improved; however, cognitive deficits are among the long-term sequelae. We hypothesize that acute lung injury leads to upregulation of cerebral cytokine synthesis. Methods After approval of the institutional and animal care committee, 20 male pigs were randomized to one of three groups: (1) Lung injury by oleic acid injection (OAI), (2) ventilation only (CTR) or (3) untreated. We compared neuronal numbers, proportion of neurons with markers for apoptosis, activation state of Ib…
Entre Trapani et Tunis. De la période du Risorgimento à la fin du Protectorat français: parcours de travailleurs et d’entrepreneurs au-delà du Canal …
2019
Sin dai tempi più antichi, il Canale di Sicilia e la città di Trapani hanno costituito un ponte naturale fra il Maghreb e la Sicilia. Il saggio mette a sistema alcuni studi sugli architetti ed imprenditori di origine trapanese che emigrarono in Tunisia fra il XVIII e XIX secolo e ne propone una lettura inedita. Il fil rouge che lega Giuseppe Abita, la famiglia di imprenditori Canino e Domenico Basciano riguarda sia la loro provenienza dalla città siciliana, ma soprattutto l'importante contributo che essi hanno trasferito nell'architettura del periodo coloniale e post-coloniale francese nel Maghreb.