Search results for "EBI"
showing 10 items of 554 documents
Simultaneous appearance of leukemoid reaction and phlegmasia cerulea dolens
2012
A leukemoid reaction is an extreme form of reactive leukocytosis defined as granulocytic leukocytosis above 50 × 109/L produced by normal bone marrow, mostly in response to systemic infection or cancer. The mechanism as to how the haematopoetic system is altered to elevate production of myeloid cells is not known. A 69-year-old man presented with phlegmasia cerulea dolens caused by massive iliofemoral thrombosis. His workout at admission revealed absolute white blood cell count of 73.4 × 109/L, with neutrophil granulocyte of 68.5 × 109/L. The new increase in white blood cell count happened at day 5 after admission, when the haematoma of the anteromedial thigh was evacuated in general anaes…
Leukocyte Rheology Before and After Chemotactic Activation in some Venous Diseases
1999
Abstract Objective: to evaluate leukocyte rheology, polymorphonuclear leukocyte (PMN) membrane fluidity and cytosolic Ca2+ concentration in subjects with post-phlebitic leg syndrome (PPS) and acute deep-venous leg thrombosis (DVT). Subjects: twenty-two subjects with leg PPS and 14 subjects with leg DVT. Methods: we evaluated the leukocyte filtration (unfractionated, mononuclear cells (MN) and PMN), the PMN membrane fluidity and the PMN cytosolic Ca2+ concentration. Subsequently, we evaluated the same PMN variables after in vitro chemotactic activation with 4-phorbol 12-myristate 13-acetate (PMA) and N -formyl-methionyl-leucyl-phenylalanine (fMLP). Results: at baseline we observed a signific…
Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.
2006
Nebivolol is a β 1 -receptor antagonist with vasodilator and antioxidant properties. Because the vascular NADPH oxidase is an important superoxide source, we studied the effect of nebivolol on endothelial function and NADPH oxidase activity and expression in the well-characterized model of angiotensin II–induced hypertension. Angiotensin II infusion (1 mg/kg per day for 7 days) caused endothelial dysfunction in male Wistar rats and increased vascular superoxide as detected by lucigenin-derived chemiluminescence, as well as dihydroethidine staining. Vascular NADPH oxidase activity, as well as expression at the mRNA and protein level, were markedly upregulated, as well as NOS III uncoupled, …
Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats
2020
Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope for therapeutic microbes. We have shown that high hepatic fat content associated with low abundance of Faecalibacterium prausnitzii in humans and, further, the administration of F. prausnitzii prevented NAFLD in mice. Here, we aimed at targeting F. prausnitzii by prebiotic xylo-oligosaccharides (XOS) to treat NAFLD. First, the effect of XOS on F. prausnitzii growth was assessed in vitro. Then, XOS was supplemented or not with high (HFD, 60% of energy from fat) or low (LFD) fat diet for 12 weeks in Wistar rats (n = 10/group). XOS increased F. prausnitzii growth, having onl…
Pero Tafur y Bertrandon de la Broquière en Constantinopla : la imagen ceremonial de María de Trebisonda y los encuentros diplomáticos en torno al con…
2018
Tras la caída de Constantinopla (1453), Pero Tafur y Bertrandon de La Broquière difunden sus libros de viajes, dos de los más importantes europeos escritos en el siglo XV. Ambos habían conocido, entre quince y veinte años antes, al emperador de Grecia, Juan VIII Paleólogo, al Papa Eugenio IV y a otros protagonistas de los concilios de Basilea (1431-1434) y Ferrara-Florencia (1438-1439), que decretaron la unión entre las iglesias romana y griega. Los viajeros fueron, así, testigos, pero también informantes y diplomáticos activos para los intentos de unión religiosa y política, que trató de reavivar el Papa Pio II tras la caída de Constantinopla (1453). Tafur y La Broquière conocieron en Cons…
Fluoruro en aguas minerales naturales envasadas en España y prevención de la caries dental
2015
ResumenObjetivoEl propósito del estudio es conocer la concentración en flúor de las aguas minerales naturales comercializadas en España para poder prevenir la caries dental sin el riesgo de causar fluorosis dental.DiseñoEstudio descriptivo y transversal a lo largo de 2012.EmplazamientoAguas minerales naturales comercializadas en España.ParticipantesTres muestras con fechas distintas de embotellado de 109 marcas de aguas minerales naturales (97 marcas españolas y 12 aguas importadas).Medición principalDeterminación analítica por cromatografía iónica del contenido en fluoruro en el agua.ResultadosLa concentración mediana de fluoruro de las aguas minerales naturales españolas es de 0,22 (rango…
Transtensional/extensional fault activity from the Mesozoic rifting to Tertiary chain building in Northern Sicily (Central Mediterranean)
2005
Extensional structures of different ages characterize the Sicilian fold-and-thrust belt. Normal faults ranging in geometry from stepped to listric and formed in different geodynamic settings significantly controlled the pattern of syn-tectonic deposits. Since Mesozoic times Sicily has experienced deformation related to the opening of the Tethys Ocean. Between the Upper Triassic and the Cretaceous normal, strike- and oblique-slip faults, developed in northern Sicily, in the framework of a transtensional deformation regime induced by the oblique rifting of the African and European continental passive margins. Since Tertiary times a reversal in the general relative plate motion induced converg…
Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cry…
2003
With the spread of the human immunodeficiency virus in the early 1980s, cryptosporidiosis was regarded as an AIDS-defining disease. As an opportunistic pathogen, the intestinal parasite Cryptosporidium parvum became an important cause of chronic diarrhoea, leading to high morbidity and mortality in immunocompromised patients. To date, no effective chemotherapy is available. With the introduction of protease inhibitors (PIs) in highly active antiretroviral therapy (HAART), the incidence of cryptosporidiosis in AIDS patients has declined substantially in western countries. We have therefore tested the effect of five PIs used in HAART on the excystation, invasion and development of the parasit…
Real-time detection of riboflavin production by Lactobacillus plantarum strains and tracking of their gastrointestinal survival and functionality in …
2019
Some strains of lactic acid bacteria (LAB) produce riboflavin, a water-soluble vitamin of the B complex, essential for human beings. Here, we have evaluated riboflavin (B2 vitamin) production by five Lactobacillus plantarum strains isolated from chicha, a traditional maize-based fermented alcoholic beverage from north-western Argentina and their isogenic riboflavin-overproducing derivatives previously selected using roseoflavin. A direct fluorescence spectroscopic detection method to quantify riboflavin production in bacterial culture supernatants has been tested. Comparison of the efficiency for riboflavin fluorescence quantification with and without prior HPLC fractionation showed that th…
Early Diagnosis of Acanthamoeba Infection during Routine Cytological Examination of Cerebrospinal Fluid
2006
ABSTRACT Early identification of Acanthamoeba in cerebrospinal fluid is mandatory to prevent fatal granulomatous amebic encephalitis. In the case presented here amebic trophozoites were detected in a routine cerebrospinal fluid sample. The antibiotic treatment and the apparently low virulence of this isolate were responsible for the benign progression of the infection.