Search results for "ECIS"
showing 10 items of 2868 documents
Home treatment of pulmonary embolism: are all the questions answered now after the HOME-PE trial?
2020
A score model for the continuous grading of early allograft dysfunction severity
2014
Early allograft dysfunction (EAD) dramatically influences graft and patient outcomes. A lack of consensus on an EAD definition hinders comparisons of liver transplant outcomes and management of recipients among and within centers. We sought to develop a model for the quantitative assessment of early allograft function [Model for Early Allograft Function Scoring (MEAF)] after transplantation. A retrospective study including 1026 consecutive liver transplants was performed for MEAF score development. Multivariate data analysis was used to select a small number of postoperative variables that adequately describe EAD. Then, the distribution of these variables was mathematically modeled to assig…
Simultaneous cardiocerebral embolization in patients with atrial fibrillation
2020
Aerobiology: an ecological indicator for early detection and control of fungal outbreaks in caves
2011
5 pages, 1 table, 13 references.
Clinical Development of Mepolizumab for the Treatment of Severe Eosinophilic Asthma: On the Path to Personalized Medicine.
2021
The development of mepolizumab, an anti-IL-5 monoclonal antibody for the treatment of severe eosinophilic asthma, is an example of a clinical development program that evolved over time based on sound, basic scientific principles. Initial clinical data on the effects of mepolizumab on lung function in a general asthmatic population were disappointing. However, it became clear that mepolizumab may be more effective against other clinical endpoints, particularly asthma exacerbations, in patients with more severe disease. Furthermore, a developing understanding of asthma disease pathobiology led to the identification of an appropriate target population and predictive biomarker for mepolizumab t…
Heart Failure with Preserved Ejection Fraction: An Urgent Need for Precision Medicine
2021
Heart failure with preserved (HFpEF) and mid-range ejection fraction (HFmrEF) constitute two heart failure categories, representing about 50–70% of the total [...]
Triage assessment of registered nurses in the emergency department
2013
Standardised triage systems have been implemented in emergency departments (EDs) to improve the efficacy of assessment strategies as performed by registered nurses (RNs). However, the exact effect the standardised triage systems have on the decision-making process remains unclear.Aim: To evaluate decision making in the triage setting before and after implementation of the Medical Emergency Triage and Treatment System Adult in one hospital's ED.Methods: A descriptive intervention design with a quantitative approach. A total of 655 patients before and 413 patients after the intervention were included. A questionnaire was used to evaluate how the RNs assessed the patients before intervention w…
Impella CP in cardiogenic shock due to acute myocardial infarction: From primary angioplasty to LIMA-LAD grafting.
2021
382 Molecular classification of endometrial carcinoma substantially changing risk-assessment: Results from a european multicentre initiative
2021
Introduction/Background* Endometrial carcinoma patient care was based on histopathologic examination for many years. However, conventional pathologic features are known to suffer from high inter-observer variability and may be irreproducible in many cases. TCGA-derived molecular classification was shown to provide clinically meaningful data and was recently introduced to ESGO/ESTRO/ESP endometrial carcinoma consensus guidelines. It was the aim of this study to quantify alterations in risk-assessment if molecular classification is added to conventional prognosticators. Methodology Consecutive primary endometrial carcinoma patients diagnosed in 2016 were identified in participating centres. O…
Digital health interventions for children with ADHD
2020
Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder characterised by a persistent pattern of symptoms of inappropriate and impaired inattention, hyperactivity, or impulsivity, with difficulties often continuing into adulthood.1 It is estimated to affect 37·1 million children and young people (aged ≤20 years) worldwide.2 Although multiple ADHD treatments are available and widely used (eg, evidence-based behaviour therapy, medications, or a combination of both),3,4 their effectiveness has been questioned because they might not fully address the needs of many children with ADHD. Barriers to evidence-based treatment for ADHD include misconceptions and stigma, time, and…