Search results for "ECK"
showing 10 items of 2091 documents
Eckhaus instability of stationary patterns in hyperbolic reaction–diffusion models on large finite domains
2022
AbstractWe have theoretically investigated the phenomenon of Eckhaus instability of stationary patterns arising in hyperbolic reaction–diffusion models on large finite domains, in both supercritical and subcritical regime. Adopting multiple-scale weakly-nonlinear analysis, we have deduced the cubic and cubic–quintic real Ginzburg–Landau equations ruling the evolution of pattern amplitude close to criticality. Starting from these envelope equations, we have provided the explicit expressions of the most relevant dynamical features characterizing primary and secondary quantized branches of any order: stationary amplitude, existence and stability thresholds and linear growth rate. Particular em…
Ultrasound hyperthermia induces apoptosis in head and neck squamous cell carcinoma: an in vitro study
2016
Background Hyperthermia is considered an efficient complement in the treatment of head and neck squamous cell carcinoma (HNSCC). Hyperthermia induces cell apoptosis in a temperature- and time-dependent manner. However, the molecular mechanism of hyperthermia remains unclear. The aim of this study was to investigate the mechanism of apoptosis induced by ultrasound hyperthermia in HNSCC cell lines HN-30 and HN-13. Material and Methods We examined the dynamic changes of early apoptosis and secondary necrosis in HN-30 and HN-13 cells treated by hyperthermia at 42°C for 10 min. We further examined mitochondrial membrane potential in vitro by ultrasound hyperthermia for different heating temperat…
Kawalerzysta, dowódca i wykładowca - szkic do biografii gen. bryg. Konstantego Druckiego-Lubeckiego (1893-1940)
2018
Celem przeprowadzonych badań było opracowanie rozszerzonego szkicu biograficznego księcia gen. bryg. Konstantego Druckiego-Lubeckiego. Dzięki zebranym dokumentom i materiałom ustalono najważniejsze fakty z życia generała, dotyczące jego pochodzenia, nauki w Cesarskim Aleksandrowskim Liceum (Lycee Imperial Alexandre) w Petersburgu, udziału w walkach o niepodległość Polski oraz kariery w kawalerii i szkolnictwie wojskowym II RP. Udostępnione przez bliskich księcia materiały, skonfrontowane ze źródłami urzędowymi i dostępnymi publikacjami, pozwoliły także na ustalenie dodatkowych okoliczności związanych z jego śmiercią z rąk NKWD w 1940 roku. Dokumenty te umożliwiły rekonstrukcję podejmowanych…
Cultural adaptation of the Smiling is Fun program for the treatment of depression in the Ecuadorian public health care system: A study protocol for a…
2021
Background Depression is one of the world's major health problems. Due to its high prevalence, it constitutes the first cause of disability among the Americas, where only a very low percentage of the population receives the adequate evidence-based psychological treatment. Internet-Based Interventions (IBIs) are a great alternative to reduce the treatment gap for mental disorders. Although there are several studies in low-and middle-income countries proving IBIs' feasibility and acceptability, there is still little evidence of the effectiveness in diverse social and cultural contexts such as Latin America. Methods Two studies will be described: Study 1 is focused on the cultural adaptation o…
Accelerated dinuclear palladium catalyst identification through unsupervised machine learning.
2021
Although machine learning bears enormous potential to accelerate developments in homogeneous catalysis, the frequent need for extensive experimental data can be a bottleneck for implementation. Here, we report an unsupervised machine learning workflow that uses only five experimental data points. It makes use of generalized parameter databases that are complemented with problem-specific in silico data acquisition and clustering. We showcase the power of this strategy for the challenging problem of speciation of palladium (Pd) catalysts, for which a mechanistic rationale is currently lacking. From a total space of 348 ligands, the algorithm predicted, and we experimentally verified, a number…
Metafora i piękno w "Iliadzie" Homera
2017
Iliada Homera jest wielowarstwową opowieścią o heroicznej przeszłości achajskiej arystokracji. Choć skażeni winą, ate, choć zaangażowani w niesprawiedliwą, łupieżczą wojnę, bohaterowie achajskiej historii dosięgają wzoru cnoty, arete – męstwa połączonego z mądrością. Wina zarówno Achajów – Achillesa i Agamemnona, jak i Trojan – Parysa i Hektora, przesłania oraz odbiera im część chwały, jaka winna wypływać z mądrego męstwa połączonego z szacunkiem dla zwyciężonych. Wina zrodzona z pokusy, której nie mogą się oprzeć jako śmiertelni, paradoksalnie obarcza ich odpowiedzialnością za zło, nad którym nie panują. Jednak spadająca na nich kara staje się ekspiacją i aktem odzyskania heroicznej cnoty.…
Squamous cell carcinoma related with dental implants. A clinical cases report
2020
One third of all cases of head and neck carcinoma (CA) concern the oral mucosa. The use of dental implants (DI) for dental rehabilitation is widely extended. However, a few studies have reported some cases with neoplasic alterations, among the tissue surrounding implants. Our aim was to analyze possible alterations at the bone-implant interface in patients with oral squamous cell carcinoma (SCC), providing new evidence that could relate or discard a possible link between these factors. We used, for the first time, different techniques, including electron microscopy and histology, to analyze the implant ´s surface and the surrounding tissue from four clinical cases with neoplasic alterations…
Using ultrasound transmission velocity to analyse the mechanical properties of teeth after in vitro, in situ, and in vivo irradiation.
2000
Ultrasound transmission velocity (UTV) in isotropic material as a measure for the modulus of elasticity was correlated to mechanical properties. Changes in micromechanical properties of radiated teeth and influence of the oral cavity were to be evaluated nondestructively. UTV was measured in extracted teeth after 36 Gy and 62 Gy of in situ (enorally, with no contact to the oral cavity) and in vitro irradiation. Relative to controls, teeth subjected to 62 Gy in vivo showed higher UTV values for dentine and enamel. Sound teeth irradiated with 60 Gy in situ also showed higher UTV values for enamel, whereas dentine values were not significantly different from those of control. The mechanical pr…
Pedagogical experiments with MathCheck in university teaching
2019
MathCheck is a relatively new online tool that gives students feedback on their solutions to elementary university mathematics and theoretical computer science exercises. MathCheck was designed with constructivism learning theory in mind and it differs from other online tools as it checks the solutions step by step and shows a counter-example if the step is incorrect. It has been in student use since the autumn of 2015 and under design-based research from the first online day. The main research questions of this study are the following. 1) How can the usage of MathCheck support the aspects of conceptual understanding and procedural fluency of constructivism learning? 2) How can MathCheck em…
From Benzofurans to Indoles: Palladium-Catalyzed Reductive Ring-Opening and Closure via β-Phenoxide Elimination
2018
International audience; Benzofurans can undergo ring-opening by a palladium-catalyzed process resulting in C−O bond breaking. Benzofuran-tethered 2-iodoanilines give synthetically interesting 2-(3-indolylmethyl)phenols in an overall reductive process. Mechanistic studies suggest that this unusual reaction proceeds by carbopalladation of benzofuran giving a 3-palladated 2,3-dihydrobenzofuran intermediate, which then fragments by an uncommon trans-elimination of the phenoxide group β to the metal. In this transformation, N,N-diisopropylethylamine (DIPEA) acts as a base and as a reducing agent: it regenerates palladium(0) from palladium(II), thus allowing catalytic turnover.