Search results for "ECK"

showing 10 items of 2091 documents

Associations of neck and shoulder pain with objectively measured physical activity and sedentary time among school-aged children

2020

Abstract Objectives The potential effects of physical activity and sedentary time on children’s increasing neck and shoulder pain are unclear. The aim of this cross-sectional study was to evaluate the associations between objectively measured physical activity or sedentary time and neck and shoulder pain in children. Methods Children (n=905; 10–15 years old) filled in an electronic questionnaire during school hours on the frequency of their neck and shoulder pain. Daytime moderate to vigorous physical activity and sedentary time were measured objectively with an ActiGraph accelerometer. A multinomial logistic regression was applied to study the associations. The results were adjusted for ag…

MaleMusculoskeletal painmedicine.medical_specialtyhartiatPhysical activitylapset (ikäryhmät)liikuntaBedtimeistuminen03 medical and health sciences0302 clinical medicineShoulder Painsedentary behaviorAccelerometryaccelerometryHumansDaily livingMedicinepain030212 general & internal medicineSex DistributionChildExercisePain symptomsSedentary timechildNeck PainSchool age childexercisebusiness.industrykipuniska030229 sport sciencesCross-Sectional StudiesAnesthesiology and Pain MedicinePhysical therapyFemaleNeurology (clinical)Sedentary BehaviorbusinessBody mass indexfyysinen aktiivisuus
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Axial neck rotation strength in neutral and prerotated postures.

2003

Abstract Objective. To characterize isometric rotation strength in the neutral and in different prerotated positions of the neck. Design. This was a descriptive study involving maximal isometric strength measurements of the cervical musculature. Background. The literature contains only a few studies pertaining to strength levels of the neck rotator muscles in the neutral position. None of these studies have dealt in detail with maximal neck strength in selected prerotation positions. Method. Twenty healthy men volunteered as subjects. Maximal axial rotation strength of the neck muscles was measured in a neutral position and bilaterally at 30° and 60° rotation using the isometric neck streng…

MaleNeck painRotationMovementPostureBiophysicsNeck rotationIsometric exerciseAnatomyRotationNeck musclesmedicine.anatomical_structureNeck MusclesMaximal strengthmedicineHumansOrthopedics and Sports MedicineRotator cuffmedicine.symptomRange of Motion ArticularRange of motionMathematicsClinical biomechanics (Bristol, Avon)
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Hydroxyurea modulates 5-fluorouracil antineoplastic activity in advanced head and neck carcinoma pretreated with chemotherapy

1992

After informed consent 21 patients with advanced head and neck cancer resistant to folinic acid/5-fluorouracil (FA/5FU + cisplatin) were treated with weekly FA/5FU plus low dose hydroxyurea (HU) to evaluate if HU could further modulate 5FU antineoplastic activity. Five patients achieved a partial response (23.8%) which was short-lived (mean duration 6.5 months). Three patients (14%) had stable disease and 13 (62%) progressed. Among responders, four patients had epidermoidal carcinoma and one had clear cell carcinoma. Treatment was well tolerated and 5FU-related toxicity was not apparently worsened by the addition of HU. The most frequent toxicities were nausea/vomiting (81%), diarrhea (52%)…

MaleOncologyCancer Researchmedicine.medical_specialtyNauseamedicine.medical_treatmentGastroenterologyDrug Administration ScheduleFolinic acidInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineCarcinomaHumansHydroxyureaPharmacology (medical)AgedAged 80 and overPharmacologyChemotherapyLeukopeniabusiness.industryMiddle Agedmedicine.diseaseSurvival RateOncologyHead and Neck NeoplasmsFluorouracilClear cell carcinomaVomitingFemaleFluorouracilmedicine.symptombusinessmedicine.drugAnti-Cancer Drugs
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Survival of Patients with Oral Cavity Cancer in Germany

2012

The purpose of the present study was to describe the survival of patients diagnosed with oral cavity cancer in Germany. The analyses relied on data from eleven population-based cancer registries in Germany covering a population of 33 million inhabitants. Patients with a diagnosis of oral cavity cancer (ICD-10: C00-06) between 1997 and 2006 are included. Period analysis for 2002-2006 was applied to estimate five-year age-standardized relative survival, taking into account patients' sex as well as grade and tumor stage. Overall five-year relative survival for oral cavity cancer patients was 54.6%. According to tumor localization, five-year survival was 86.5% for lip cancer, 48.1% for tongue c…

MaleOncologyHealth ScreeningDatabases FactualEpidemiologyOral Mucosal CancersOral DiseasesGermanyStage (cooking)Young adultSkin TumorsMouth neoplasmeducation.field_of_studyMultidisciplinaryRelative survivalQRMiddle Agedmedicine.anatomical_structureOncologyHead and Neck SurgeryMedicineFemaleMouth NeoplasmsPublic HealthAlcoholCancer EpidemiologyResearch ArticleAdultmedicine.medical_specialtyTobacco ControlAdolescentScienceOral MedicinePopulationYoung AdultTongueInternal medicinemedicineHumanseducationSurvival analysisAgedbusiness.industryCancers and NeoplasmsCancermedicine.diseaseSurvival AnalysisSurgeryDentistrySurgeryPreventive MedicinebusinessPLoS ONE
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Head and neck paragangliomas: Report of 175 patients (1989-2010)

2011

Attention of the otorhinolaryngologist needs to be drawn to the versatile aspects of head and neck paragangliomas (PGLs).This study is a retrospective, nonrandomized clinical study of all 175 individuals with PGLs treated in our department between 1989 and 2010. A genetic analysis was performed on 86 patients.The 175 patients presented 224 head and neck PGLs as well as 2 thyroid papillary carcinomas. Genetic analysis resulted in 1 patient positive for a von Hippel-Lindau (VHL) gene mutation and 34 for succinate dehydrogenase (SDH) gene mutations (22 SDHD, 7 SDHC, and 5 SDHB), 12 of the latter carrying a novel mutation. Thirty-three patients (18.9%) had multiple PGLs and 11 patients (6.3%) h…

MaleOncologyHeterozygotemedicine.medical_specialtyPathologyMEDLINEMalignancyNeoplasms Multiple PrimaryParagangliomaInternal medicineCarcinomamedicineHumansHead and neckRetrospective Studiesbusiness.industryRetrospective cohort studyHeterozygote advantagemedicine.diseaseCarcinoma PapillarySuccinate DehydrogenaseOtorhinolaryngologyHead and Neck NeoplasmsVon Hippel-Lindau Tumor Suppressor ProteinMutationMutation (genetic algorithm)FemalebusinessHead & Neck
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Role of Kras Status in Patients with Metastatic Colorectal Cancer Receiving First-Line Chemotherapy plus Bevacizumab: A TTD Group Cooperative Study

2012

Background: In the MACRO study, patients with metastatic colorectal cancer (mCRC) were randomised to first-line treatment with 6 cycles of capecitabine and oxaliplatin (XELOX) plus bevacizumab followed by either single-agent bevacizumab or XELOX plus bevacizumab until disease progression. An additional retrospective analysis was performed to define the prognostic value of tumour KRAS status on progression-free survival (PFS), overall survival (OS) and response rates. Methodology/Principal Findings: KRAS data (tumour KRAS status and type of mutation) were collected by questionnaire from participating centres that performed KRAS analyses. These data were then cross-referenced with efficacy da…

MaleOncologyOrganoplatinum Compoundsendocrine system diseasesEpidemiologyColorectal cancer:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]DeoxycytidineMetastasis:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Antineoplastic Combined Chemotherapy ProtocolsPathologyMedicineNeoplasm Metastasisgeneslcsh:Sciencemediana edad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols [Medical Subject Headings]Aged 80 and overanciano:Chemicals and Drugs::Organic Chemicals::Organometallic Compounds::Organoplatinum Compounds [Medical Subject Headings]Cancer Risk FactorsClinical Pharmacologyprotocolos de quimioterapia antineoplásica combinadaColon AdenocarcinomaPronósticoCombination chemotherapyadultoPrognosisBevacizumabOxaliplatinpronósticoOncologyMedicineOncology Agentsmedicine.medical_specialty:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings]FluorouraciloBevacizumab:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Pyrimidines::Pyrimidine Nucleosides::Cytidine::Deoxycytidine [Medical Subject Headings]:Check Tags::Male [Medical Subject Headings]Molecular GeneticsCapecitabine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies Monoclonal::Antibodies Monoclonal Humanized [Medical Subject Headings]Gastrointestinal TumorsGenetics:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansClinical TrialsBiologyneoplasmsCapecitabineAgedlcsh:R:Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Neoplasm::Oncogenes::Proto-Oncogenes::Genes ras [Medical Subject Headings]medicine.diseasedigestive system diseasesOxaliplatin:Check Tags::Female [Medical Subject Headings]PharmacogeneticsMutationlcsh:QfluorouraciloMultivariate analysisDesoxicitidinahumanosCancer Treatment:Named Groups::Persons::Age Groups::Adult::Aged::Aged 80 and over [Medical Subject Headings]lcsh:Medicinemedicine.disease_causeNeoplasias colorrectalesSurgical oncologyBasic Cancer Research:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Pyrimidines::Pyrimidinones::Uracil::Fluorouracil [Medical Subject Headings]Clinical Trials (Cancer Treatment)metástasis neoplásicaMetástasis neoplásicaMultidisciplinaryMiddle AgedGenetic EpidemiologyProtocolos de quimioterapia antineoplásica combinadaFemaleAntiangiogenesis TherapyFluorouracilKRASColorectal NeoplasmsResearch Articlemedicine.drugAdultDrugs and DevicesClinical Pathologyneoplasias colorrectalesClinical Research DesignGenetic Causes of CancerAntibodies Monoclonal HumanizedAntibodiesRectal CancerAntibody TherapyDiagnostic MedicineInternal medicine:Diseases::Neoplasms::Neoplastic Processes::Neoplasm Metastasis [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]mutaciónClinical GeneticsMutaciónbusiness.industryPharmacoepidemiologyCancers and NeoplasmsHuman GeneticsChemotherapy and Drug TreatmentdesoxicitidinaGenes rasanticuerposGenetics of Diseasebusinesscompuestos organoplatinoPLoS ONE
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Clinical-pathological and sociodemographic factors associated with the distant metastasis and overall survival of oral cavity and oropharynx squamous…

2020

Background The objective of this study was to evaluate the influence of clinical-pathological and sociodemographic factors on the prevalence of distant metastasis (DM) and overall survival in patients with oral cavity and oropharynx squamous cell carcinoma (OOSCC). Material and Methods Cross-sectional study based on the records of 404 OOSCC patients evaluated for DM, covering the period 2000-2014. We analysed the influence of age, sex, level of schooling, primary tumor subsite, treatment, marital status, family history of cancer, history of smoking and alcohol consumption, type of health care coverage (private vs. public) and overall survival. Findings were submitted to Fisher’s exact test,…

MaleOncologymedicine.medical_specialtyCross-sectional study03 medical and health sciences0302 clinical medicineInternal medicinemedicineCarcinomaHumansFamily historyGeneral DentistryAgedNeoplasm StagingRetrospective StudiesOral Medicine and Pathologybusiness.industryProportional hazards modelResearchCancerRetrospective cohort study030206 dentistryPrognosis:CIENCIAS MÉDICAS [UNESCO]medicine.diseasePrimary tumorOropharyngeal NeoplasmsExact testCross-Sectional StudiesOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Olfaction in chemotherapy for head and neck malignancies

2015

Abstract Objective Systemic chemotherapy for different malignancies occurs alongside various side effects, including reduced sensory function. To date, little is known about the effect of chemotherapeutic agents on olfaction. The aim of this study was to provide new data about changes in sense of smell during chemotherapy among patients with advanced squamous cell carcinomas of the head and neck region. Methods In a prospective, controlled cohort study of patients undergoing up to three courses of chemotherapy (cis- or carboplatin, 5-fluorouracil and docetaxel), olfaction was evaluated prior to and directly following completing a cycle, as well as 3 weeks later with the beginning of the nex…

MaleOncologymedicine.medical_treatmentDocetaxelSystemic therapyCarboplatinCohort StudiesOlfaction Disorderschemistry.chemical_compound0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsProspective Studies030212 general & internal medicineAged 80 and overSmokingAge FactorsGeneral MedicineMiddle AgedDocetaxelHead and Neck NeoplasmsSensory Thresholds030220 oncology & carcinogenesisCarcinoma Squamous CellFemaleTaxoidsFluorouracilmedicine.drugCohort studyAdultmedicine.medical_specialtyDifferential ThresholdOlfaction03 medical and health sciencesInternal medicinemedicineHumansLaryngeal NeoplasmsAgedCisplatinChemotherapySquamous Cell Carcinoma of Head and Neckbusiness.industryCancerPharyngeal Neoplasmsmedicine.diseaseCarboplatinSurgeryOtorhinolaryngologychemistryControlled Before-After StudiesSurgeryCisplatinbusinessAuris Nasus Larynx
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Interface transition checklists in spinal surgery

2016

Issue Recently, quality tools have been promoted to improve patient safety and process efficiency in healthcare. While surgeons primarily focused on surgical issues, like infection rates or implant design, we introduced pre-admission and preoperative checklists in the early 2000s. Initial assessment To assess the efficiency of these tools in a neurosurgical department, we performed a survey of all spinal instrumentation patients operated in 2011 ( n  = 147). The results revealed several problems. Choice of solution We consequently redesigned the checklists accompanied by flanking measures, such as written  and online accessible standards. Furthermore, the staff was trained to use the update…

MaleOperating Roomsmedicine.medical_specialtyQuality Assurance Health CarePreoperative care03 medical and health sciencesPatient safety0302 clinical medicineSurveys and QuestionnairesPreoperative CareHealth careHumansMedicine030212 general & internal medicineSeven Basic Tools of QualitySpinal instrumentationbusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthGeneral MedicineMiddle Agedmedicine.diseaseSpineChecklistSpinal surgeryChecklistSurgeryWorkflowFemalePatient SafetyMedical emergencybusiness030217 neurology & neurosurgeryInternational Journal for Quality in Health Care
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Is the injection of tramadol effective at control of pain after impacted mandibular third molar extractions? A systematic review and meta-analysis.

2022

Third molar extraction is among the most common surgical procedures performed by oral-maxillofacial surgeons. Postoperative pain, swelling and trismus are common, especially in wisdom teeth, due to trauma to local tissues and the duration of the surgical procedure, among other factors. This systematic review was conducted in accordance with the ?Preferred Reporting Items for Systematic Reviews and Meta-Analyses? in order to answer the focused question: ?Is the local submucosal injection of tramadol effective at the control of postoperative pain in patients submitted to impacted mandibular third molar extractions??. We analyzed papers published until March 30, 2021 in the MEDLINE|PubMed, Web…

MalePain PostoperativeAnalgesicsTooth Impactedhead and neckpediatricOtorhinolaryngologyhistologicimmunohistochemistryTooth ExtractionHumansEdemaSurgeryFemaleMolar ThirdTrismusrhabdomyosarcomaGeneral DentistryUNESCO:CIENCIAS MÉDICASTramadolMedicina oral, patologia oral y cirugia bucal
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