Search results for "ECL"
showing 10 items of 1262 documents
Tool integration in Eclipse
2005
Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action
2015
Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…
Outdoor environment, mobility decline and quality of life among older people
2011
The Universal Declaration of Human Rights
2023
This publication has been funded through the Unesco Chair 2023 of the University of Valencia. The document addresses the importance of the Universal Declaration of Human Rights as a global framework for the protection of human rights. It mentions the five categories of rights: civil, political, economic, social, and cultural. The current challenges in human rights protection, such as violence, discrimination, and online privacy, are also highlighted.
Alarmist by bad design: Strongly popularized unsubstantiated claims undermine credibility of conservation science
2019
“Unless we change our ways of producing food, insects as a whole will go down the path of extinction in a few decades.” or “Our work reveals dramatic rates of decline that may lead to the extinction of 40% of the world's insect species over the next few decades.” These are verbatim conclusions of the recent paper by Sánchez-Bayoa and Wyckhuys (2019) in Biological Conservation. Because of fundamental methodological flaws, their conclusions are unsubstantiated. Like noted by The Guardian, the conclusions of the paper were set out in unusually forceful terms for a peer-reviewed scientific paper. The current case…
Voiko representaatioilla olla kahta vastaavuuden suuntaa?
2013
Preeklampsi i Fit for fødsel
2016
Masteroppgave folkehelsevitenskap - Universitetet i Agder 2016 Background:Preeclampsia is a serious complication of pregnancy, affectingtwo to eight percentages of all pregnanciesworldwide. Important aspects of the causal mechanisms of preeclampsia are still unknown. It is however reason to believe that preeclampsia consists of several subtypes and various causal mechanisms canbe involved. The role of obesity, excessive gestational weight gain and maternal diet in the risk of preeclampsia has recently received increased attention.Thesis question:Are there differences regarding gestational weight gain, select blood sample parametres and dietary habits between primiparous women who develop pr…
“Status quaestionis” sulle «Egloghe» dantesche. A proposito di un recente volume
2022
Breve rassegna sullo stato delle edizioni delle «Egloghe» di Dante Alighieri e dei principali studi a esse dedicati, a proposito della pubblicazione del volume di A. Renker, Streit um Vergil. Eine poetologische Lektüre der “Eklogen” Giovanni del Virgilios und Dante Alighieris, Stuttgart 2021. Brief review on the state of the editions of Dante Alighieri’s «Eclogues» and the main studies dedicated to them, regarding the publication of the volume by A. Renker, Streit um Vergil. Eine poetologische Lektüre der “Eklogen” Giovanni del Virgilios und Dante Alighieris, Stuttgart 2021.
Recensione ad A. RENKER, Streit um Vergil. Eine poetologische Lektüre der “Eklogen” Giovanni del Virgilios und Dante Alighieris, Stuttgart 2021
2022
Recensione al volume: A. RENKER, Streit um Vergil. Eine poetologische Lektüre der “Eklogen” Giovanni del Virgilios und Dan-te Alighieris, Stuttgart 2021 Review of the volume: A. RENKER, Streit um Vergil. Eine poetologische Lektüre der “Eklogen” Giovanni del Virgilios und Dante Alighieris, Stuttgart 2021