Search results for "ECL"
showing 10 items of 1262 documents
Sulle tracce di Ovidio epico? Contese tra padri e figli in Ps. Quint. decl. 258
2018
In the Minor Declamation 258 it is possible to notice some echoes of the Armorum iudicium of Ov. met. xiii 1-383, an episode whose success in Greece and Rome dates back to the Cyclic poems. Porcius Latro, the famous rhetorician and teacher of Ovid, chose this subject for one of his declamations and provided his pupil with a model: in fact, as showed by Sen. contr. ii 2, 8, the poet borrowed from the rhetor some literal expressions. We can also remember Sen. contr. x and Calp. decl. 21, two of the most important texts where the motifs of family disputes and reward for viri fortes are re-elaborated, in different ages. Therefore, the Minor declamation 258 is one of these interesting adaptation…
El palacete de Torrent: el chalet de la familia Giner-Cortina del arquitecto José Mª Manuel Cortina Pérez (1919-2009)
2009
Este artículo recupera la memoria del Palacete de Torrent, que fue diseñado y construido entre 1918 y 1919 por el importante arquitecto valenciano José Mª Manuel Cortina Pérez, para su hermana Elvira María Salomé y su cuñado José Giner y Viguer, un conocido industrial de Valencia. La elección de Torrent se debe a que gracias a la implantación del trenet y del tranvía a finales del siglo XIX, esta población destacaba como una de las mejores poblaciones de las cercanías de Valencia, atrayendo a familias muy distinguidas de la ciudad, que tenían casa en esta agradable población. Este estudio incide en la importancia del Chalet de la familia Giner-Cortina y en la genialidad que el arquitecto le…
La escritura en la Cartuja (análisis diacrónico a través de las constituciones)
1983
Educar para la salud en tiempos de pandemia
2021
La experiencia de la pandemia que estamos viviendo exige repensar la educación para la salud. En este trabajo lo hacemos a partir de dos conceptos procedentes de la Declaración Universal de los Derecho Humanos: primero, entender que el fin de la educación es el pleno desarrollo de la persona; y segundo, que los deberes para con la comunidad contribuyen a ese desarrollo. A partir de ellos, defendemos una concepción de la educación para la salud basada en el carácter relacional del ser humano, en la relevancia de los determinantes sociales de la salud y en los peligros del entorno digital, a pesar de los enormes beneficios que ha aportado durante la pandemia.
Moros y cristianos. De la batalla festiva a la discursiva
2008
Hace poco más de un año se acordaba en España admitir a trámite en el Congreso de los Diputados la proposición no de ley del Grupo Parlamentario Popular relativa a la proclamación de las "fiestas de moros y cristianos" como obras maestras del patrimonio oral e inmaterial de la humanidad. La solicitud se contextualiza en la democratización y universalización que el patrimonio ha experimentado y se explica por la vertiente cada vez más mercantilista de los procesos de patrimonialización. En el caso que nos ocupa la presentación estuvo envuelta en una interesante discusión política sobre la "tradición", la "libertad" y la "amenaza". Este artículo analiza la polémica sobre estas fiestas y su pr…
Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34⁺ cells in a xenograft model
2012
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), delivered as a membrane-bound molecule expressed on the surface of adenovirus-transduced CD34+ cells (CD34-TRAIL+), was analyzed for its apoptotic activity in vitro on 12 breast cancer cell lines representing estrogen receptor-positive, HER2+ and triple-negative (TN) subtypes and for its effect on tumor growth, vascularization, necrosis, and lung metastasis incidence in NOD/SCID mice xenografted with the TN breast cancer line MDA-MB-231. Mesenchymal TN cell lines, which are the richest in putative tumor stem cells among the different breast cancer cell subtypes, were the most susceptible to apoptosis induced by CD34-TRAIL+ cel…
Predicting Lung Deposition of Extrafine Inhaled Corticosteroid-Containing Fixed Combinations in Patients with Chronic Obstructive Pulmonary Disease U…
2021
Background: Functional respiratory imaging (FRI) is a computational fluid dynamics-based technique using three-dimensional models of human lungs and formulation profiles to simulate aerosol deposition. Methods: FRI was used to evaluate lung deposition of extrafine beclomethasone dipropionate (BDP)/formoterol fumarate (FF)/glycopyrronium bromide (GB) and extrafine BDP/FF delivered through pressurized metered dose inhalers and to compare results with reference gamma scintigraphy data. FRI combined high-resolution computed tomography scans of 20 patients with moderate-to-severe chronic obstructive pulmonary disease (mean forced expiratory volume in 1 second 42% predicted) with in silico comput…
Identification of novel mutations in the ABCA12 gene, c.1857delA and c.5653–5655delTAT, causing harlequin ichthyosis
2013
Abstract Harlequin ichthyosis (HI) is a severe autosomal recessive developmental disorder of the skin that is frequently but not always fatal in the first few days of life. In HI, mutations in both ABCA12 gene alleles must have a severe impact on protein function and most mutations are truncating. The presence of at least one nontruncating mutation (predicting a residual protein function) usually causes a less severe congenital ichthyosis (lamellar ichthyosis or congenital ichthyosiform erythroderma). Here we report on a girl with severe HI diagnosed by prenatal ultrasound at 33 5/7 week gestation. Ultrasound findings included ectropion, eclabium, deformed nose, hands and feet, joint contra…
2013
Cortical function is impaired in various disorders of the central nervous system including Alzheimer’s disease, autism and schizophrenia. Some of these disorders are speculated to be associated with insults in early brain development. Pericytes have been shown to regulate neurovascular integrity in development, health and disease. Hence, precisely controlled mechanisms must have evolved in evolution to operate pericyte proliferation, repair and cell fate within the neurovascular unit (NVU). It is well established that pericyte deficiency leads to NVU injury resulting in cognitive decline and neuroinflammation in cortical layers. However, little is known about the role of pericytes in pathop…
Determination of neuronal antibodies in suspected and definite Creutzfeldt-Jakob disease
2014
IMPORTANCE: Creutzfeldt-Jakob disease (CJD) and autoimmune encephalitis with antibodies against neuronal surface antigens (NSA-abs) may present with similar clinical features. Establishing the correct diagnosis has practical implications in the management of care for these patients. OBJECTIVE: To determine the frequency of NSA-abs in the cerebrospinal fluid of patients with suspected CJD and in patients with pathologically confirmed (ie, definite) CJD. DESIGN, SETTING, AND PARTICIPANTS: A mixed prospective (suspected) and retrospective (definite) CJD cohort study was conducted in a reference center for detection of NSA-abs. The population included 346 patients with suspected CJD and 49 pati…