Search results for "ECOLOGIA"
showing 10 items of 1399 documents
Minimally Invasive Approaches in Locally Advanced Cervical Cancer Patients Undergoing Radical Surgery After Chemoradiotherapy: A Propensity Score Ana…
2020
Abstract Purpose Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical surgery (MI-RS) compared with open radical surgery (O-RS). Patients and Methods Data for stage IB2–IVA cervical cancer patients managed by CT/RT and RS were retrospectively analyzed. Results Beginning with 686 patients, propensity score matching resulted in 462 cases (231 per group), balanced for FIGO stage, lymph node status, histotype, tumor grade, and clinical respons…
Tobacco smoking and risk of endometriosis: a systematic review and meta-analysis
2014
Objective Since conflicting results have been published on the role of tobacco smoking on the risk of endometriosis, we provide an up-to-date summary quantification of this potential association. Design We performed a PubMed/MEDLINE search of the relevant publications up to September 2014, considering studies on humans published in English. We searched the reference list of the identified papers to find other relevant publications. Case–control as well as cohort studies have been included reporting risk estimates on the association between tobacco smoking and endometriosis. 38 of the 1758 screened papers met the inclusion criteria. The selected studies included a total of 13 129 women diagn…
Robotic Versus Laparoscopic Staging for Early Ovarian Cancer: A Case-Matched Control Study.
2017
Abstract Study Objective To evaluate the feasibility, surgical outcome, and oncologic results observed after robotic staging compared with conventional laparoscopic staging for patients with early-stage ovarian cancer patients. Design A retrospective cohort study (Canadian Task Force classification II-2). Setting Catholic University of the Sacred Heart, Rome, Italy. Patients Ninety-six patients underwent minimally invasive staging for presumed stage I ovarian cancer; 32 underwent the robotic approach (cases), and 64 underwent the laparoscopic approach (controls). Measurements and Main Results There was no statistically significant difference between the 2 approaches with regard to final Fed…
Optimized culture conditions for tissue explants of uterine leiomyoma
2012
Background Uterine leiomyomas are the most common benign tumours in women, which arise from smooth muscle cells of the uterine myometrium and usually are multicentric. In spite of their frequency pathogenesis is widely unknown, mainly due to the absence of a suitable model system. We describe the systematic optimization of culturing leiomyoma tissue explants in an economical and effective ex vivo system. Methods Different concentrations of oxygen, different media, sera, hormones, and growth factor supplements were tested. Immunohistochemical stainings with antibodies against hormone receptors as well as specifying proliferation and apoptotic indices and real-time PCR were performed. Results…
Cell-Free Fetal DNA and Non-Invasive Prenatal Diagnosis of Chromosomopathies and Pediatric Monogenic Diseases: A Critical Appraisal and Medicolegal R…
2022
Cell-free fetal DNA (cffDNA) analysis is a non-invasive prenatal diagnostic test with a fundamental role for the screening of chromosomic or monogenic pathologies of the fetus. Its administration is performed by fetal DNA detection in the mother’s blood from the fourth week of gestation. Given the great interest regarding its validation as a diagnostic tool, the authors have set out to undertake a critical appraisal based on a wide-ranging narrative review of 45 total studies centered around such techniques. Both chromosomopathies and monogenic diseases were taken into account and systematically discussed and elucidated. Not surprisingly, cell-free fetal DNA analysis for screening purposes …
Discursos y percepciones en torno a la naturaleza protegida. El Parque natural del Estrecho
2019
Definir espacios naturales protegidos no es una tarea sencilla. Hemos asistido a una explosión sin precedentes de los mismos, que afecta tanto a su número como a su extensión territorial. Desde un prisma institucional podemos afirmar que es una demarcación administrativa, establecida con la finalidad de favorecer la conservación de la naturaleza, creada bajo la idea de preservar un enclave o una porción de la naturaleza que se considera privilegiada. Sin embargo, fuera de este prisma, asumimos que las áreas protegidas conllevan procesos complejos que entran en conflicto con la reduccionista interpretación medioambiental. Ésta afecta tanto al territorio como a sus habitantes, regulando la ‘n…
Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in‐soil organisms
2017
Abstract Following a request from EFSA, the Panel on Plant Protection Products and their Residues developed an opinion on the science behind the risk assessment of plant protection products for in‐soil organisms. The current risk assessment scheme is reviewed, taking into account new regulatory frameworks and scientific developments. Proposals are made for specific protection goals for in‐soil organisms being key drivers for relevant ecosystem services in agricultural landscapes such as nutrient cycling, soil structure, pest control and biodiversity. Considering the time‐scales and biological processes related to the dispersal of the majority of in‐soil organisms compared to terrestrial non…
L'uomo e il suo ambiente. Al di là dell'opposizione natura/cultura
2021
Il saggio rappresenta la prosecuzione delle ultime ricerche di Claude Calame, grecista di fama mondiale: dopo il Prometeo genetista (Sellerio, Palermo 2016, ed. or. Paris 2011), adesso lo studioso svizzero propone una riflessione sui rapporti tra l’essere umano e il suo ambiente, maturata sulla base del serrato confronto tra l’idea originaria, greca, di physis e la nozione di ‘natura’ per come essa si è sviluppata a partire dal pensiero illuministico e deterministico. Dei cinque capitoli in cui il saggio è complessivamente strutturato, il primo (dal titolo En Grèce ancienne : l’homme et son milieu) ricostruisce con accuratezza storico-filologica e acume critico il concetto greco di physis, …
Molecular markers and endometrial cancer
2022
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Late Pleistocene vertebrate - bearing deposits at San Teodoro Cave (North-Eastern Sicily): Preliminary data on faunal diversification and chronology
2008
Abstract This paper deals with the chronology and the possible correlations among levels of different excavated areas in the Pleistocene vertebrate-bearing deposits at the large San Teodoro Cave (North-Eastern Sicily). Two trenches have been excavated along the eastern side of the cave, located at a distance from the entrance, respectively, of 8 m ( α trench) and 28 m ( β trench) and at different depths. Lithological features, biometrical data from small mammals and ecological data from molluscs point to similar environmental conditions for the α trench deposits and those located along the eastern wall of the cave in the eastern part of the β trench. The same evidence, and the taphonomic fe…