Search results for "EES"
showing 10 items of 2276 documents
Asymmetric synthesis of functionalized tetrahydrofluorenones via an NHC-catalyzed homoenolate Michael addition
2018
The first example of an N-heterocyclic carbene-catalyzed asymmetric desymmetrization of enal-tethered cyclohexadienones via an intramolecular homoenolate Michael addition/esterification reaction is described. This new protocol offers a direct entry to various functionalized tetrahydrofluorenones with three contiguous stereocenters in high yields, good diastereoselectivities and excellent enantioselectivities.
Synthesis of N‐Fused Indolines via Copper (II)‐Catalyzed Dearomatizing Cyclization of Indoles
2021
Advanced synthesis & catalysis 363(12), 3121-3126 (2021). doi:10.1002/adsc.202100290
Solid state conformational behavior and interactions of a series of aromatic oligoamide foldamers
2016
The topic of this thesis is aromatic oligoamide foldamers. The literary review of the thesis discusses the general features of foldamers and their design and then focuses on the specific examples of aromatic oligoamide foldamers. The experimental part of the thesis discusses the design and preparation of a family of aromatic oligoamide foldamers that can adopt a helical conformation. The folding is directed by intramolecular hydrogen bonding and stabilized by intramolecular aromatic interactions. The focus of the thesis is the analysis of the solid state conformations of ten foldamer analogues. The analysis is based on forty different crystal structures which are determined using single cry…
De novo Synthesis of Chemical Defenses in an Aposematic Moth
2018
Many animals protect themselves from predation with chemicals, both self-made or sequestered from their diet. The potential drivers of the diversity of these chemicals have been long studied, but our knowledge of these chemicals and their acquisition mode is heavily based on specialist herbivores that sequester their defenses. The wood tiger moth (Arctia plantaginis, Linnaeus, 1758) is a well-studied aposematic species, but the nature of its chemical defenses has not been fully described . Here, we report the presence of two methoxypyrazines, 2-sec-butyl-3-methoxypyrazine and 2-isobutyl-3-methoxypyrazine, in the moths’ defensive secretions. By raising larvae on an artificial diet, we confir…
X-Ray structure, Hirshfeld analysis and DFT studies of two new hits of triazolyl-indole bearing alkylsulfanyl moieties
2021
Two new hits of triazolyl-indole containing two different alkylsulfanyl analogues named tert-butyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 2, and ethyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 3 were synthesized via reaction of 4-amino-5-(1H-indol-2-yl)-1,2,4-triazol-3(2H)-thione 1 with tert-butyl bromoacetate and ethyl chloroacetate in the presence of base (Et3N). The molecular structure of 2, and 3 was confirmed by single-crystal X-ray diffraction and 1H/13C- NMR spectroscopic techniques. In compound 2, the molecular packing depends on significant O...H (9.3%), N...H (12.4%) and S...H (3.1%) as well as relatively weak C...H (14.1%), S...C (…
Hypotheses engineering : first essential steps of experiment-driven software development
2019
Recent studies have proposed the use of experiments to guide software development in order to build features that the user really wants. Some authors argue that this approach represents a new way to develop software that is different from the traditional requirement-driven one. In this position paper, we propose the discipline of Hypotheses Engineering in comparison to Requirements Engineering, highlighting the importance of proper handling hypotheses that guide experiments. We derive a set of practices within this discipline and present how the literature has tackled them up to now. Finally, we propose a set of research questions that could guide future work towards helping practitioners. …
Preču zīmes atcelšanas un atzīšanas par spēkā neesošu procedūras ieviešana Rūpnieciskā īpašuma apelācijas padomē, pamatojoties uz Eiropas Parlamenta …
2018
Darbā vispārīgi tiek apskatīta Rūpnieciskā īpašuma apelācijas padomes strīdu izskatīšanas pāreja no administratīvā procesa uz civilprocesu, kā arī Rūpnieciskā īpašuma apelācijas padomes atbilstība kvazi tiesas un prejudiciālo nolēmumu prasīšanas kritērijiem. Darba teorētiskā daļa tiek attiecināta uz atcelšanas un atzīšanas par spēkā neesošu procedūru ieviešanu Rūpnieciskā īpašuma apelācijas padomē, izvērtējot to līdzību jau pastāvošajai iebildumu procedūrai. Pētījuma mērķis ir aplūkot minētās procedūras un noskaidrot nepieciešamos grozījumus normatīvajā regulējumā, ieviešot atcelšanas un atzīšanas par spēkā neesošu procedūras, kā arī konstatēt, vai Rūpnieciskā īpašuma apelācijas padomi var …
Theoretical and experimental studies of some main group compounds : from closed shell interactions to singlet diradicals and stable radicals
2012
Acquiring knowledge of different interactions within and between molecules is a fascinating undertaking as it not only deepens our understanding of chemical bonding but also offers insight into electronic structures, molecular properties and the connections between these two. This dissertation combines together three main group chemistry related topics within the aforementioned theme. Research presented in the first third of this dissertation describes wave function and density functional theory studies of weak inter- and intramolecular interactions in pnictogen-based dimers X3Pn···PnX3 (Pn = N-Bi; X = F-I), dithallenes RTlTlR (R = H, Me, tBu, Ph) and octachalcogen dications Ch82+ (Ch = S, …
Actividad Bancaria, Reestructuracion y Creacion de Bancos Malos
2015
La reciente crisis financiera ha favorecido que la sociedad debatiera sobre los vicios y virtudes de los diferentes procesos de reestructuración bancaria, y el proceso de creciente concentración en los sistemas financieros (con reducción del número de entidades financieras), ha generado numerosos interrogantes en torno a la inestabilidad sistémica, o a los bancos demasiado grandes para caer. Las entidades financieras ofrecen peculiaridades de naturaleza contable y de gobierno corporativo que justifican su análisis pormenorizado. Existen determinadas asimetrías en el reparto de responsabilidades y rentas generadas en los procesos de reestructuración bancarias y sus diferentes hojas de ruta s…
Ocena jednorodności zanieczyszczenia kory drzew liściastych metalami ciężkimi
2018
Celem badań była ocena jednorodności zanieczyszczenia metalami ciężkimi (Ni, Cu, Zn, Cd i Pb) kory drzew liściastych pobranej z lasu mieszanego na terenie gminy Ozimek (województwo opolskie). W ramach biomonitoringu pasywnego pobrano próbki kory z trzech gatunków drzew liściastych: z brzozy brodawkowatej (Betula pendula Roth.), buka zwyczajnego (Fagus sylvatica L.) oraz z dębu szypułkowego (Quercus robur L.). Metale ciężkie oznaczono za pomocą absorpcyjnej spektrometrii atomowej (AAS). Na podstawie przeprowadzonych badań można jednoznacznie stwierdzić, że kora drzew wykorzystanych do badań różni się pod względem stężeń metali ciężkich. Największe średnie zawartości Cu, Zn, Cd i Pb występują…