Search results for "EFB"

showing 2 items of 2 documents

HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb

2019

International audience; How nuclear proteins diffuse and find their targets remains a key question in the transcription field. Dynamic proteins in the nucleus are classically subdiffusive and undergo anomalous diffusion, yet the underlying physical mechanisms are still debated. In this study, we explore the contribution of interactions to the generation of anomalous diffusion by the means of fluorescence spectroscopy and simulation. Using interaction-deficient mutants, our study indicates that HEXIM1 interactions with both 7SK RNA and positive transcription elongation factor b are critical for HEXIM1 subdiffusion and thus provides evidence of the effects of protein-RNA interaction on molecu…

Models MolecularAnomalous diffusion[SDV]Life Sciences [q-bio]PopulationBiophysicsPlasma protein bindingDiffusion03 medical and health sciences0302 clinical medicineCell Line Tumor7SK RNAmedicineHumansComputer SimulationPositive Transcriptional Elongation Factor BNuclear proteinP-TEFbeducationComputingMilieux_MISCELLANEOUS030304 developmental biologyCell Nucleus0303 health sciencesMolecular diffusioneducation.field_of_studyChemistryRNA-Binding ProteinsArticles[SDV] Life Sciences [q-bio][SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry Molecular Biology/BiophysicsSpectrometry Fluorescencemedicine.anatomical_structureBiophysicsRNA Long NoncodingNucleus030217 neurology & neurosurgeryProtein BindingTranscription Factors
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Cybersecurity Attacks on Software Logic and Error Handling Within ADS-B Implementations: Systematic Testing of Resilience and Countermeasures

2022

Automatic Dependent Surveillance-Broadcast (ADS-B) is a cornerstone of the next-generation digital sky and is now mandated in several countries. However, there have been many reports of serious security vulnerabilities in the ADS-B architecture. In this paper, we demonstrate and evaluate the impact of multiple cyberattacks on ADS-B via remote radio frequency links that affected various network, processing, and display subsystems used within the ADS-B ecosystem. Overall we implemented and tested 12 cyberattacks on ADS-B in a controlled environment, out of which 5 attacks were presented or implemented for the first time. For all these attacks, we developed a unique testbed that consisted of 1…

vulnerabilitiesATCcybersecurity1090MHzlentoliikenneAerospace Engineeringcountermeasuresavionics978MHzdatalinkATMpentestingaviationexperimental platformElectrical and Electronic EngineeringUATlennonjohtoEFBkyberturvallisuusverkkohyökkäyksetlennonvarmistusADS-B1090ESIEEE Transactions on Aerospace and Electronic Systems
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