Search results for "EFFICACY"

showing 10 items of 588 documents

Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Coronavirus COVID-19 Pneumonia SARS-CoV-2 TocilizumabGCA Giant cell arteritispJIA Pediatric juvenile idiopathic arthritislaw.inventionchemistry.chemical_compound0302 clinical medicineRandomized controlled triallawMedicine030212 general & internal medicineClinical efficacyCPAP Continuous positive airway pressureCOVID-19 Coronavirus disease 2019IDSA Infectious Diseases Society of AmericaRA Rheumatoid arthritisTocilizumabIMV Invasive mechanical ventilationsJIA Juvenile idiopathic arthritisAIFA Agenzia Italiana del FarmacoPulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEAntibodies Monoclonal HumanizedNIH U.S. National Institutes of HealthArticleWHO World Health OrganizationSIMIT Italian Society of Infectious and Tropical disease03 medical and health sciencesTocilizumabARDS Acute respiratory distress syndromeAnimalsHumansIn patientIntensive care medicineTocilizumab ; COVID-19 ; Pneumonia ; SARS-CoV-2 ; Coronaviruslcsh:RC705-779business.industryCRS CAR-T cell-induced cytokine release syndromeInterleukin-6SARS-CoV-2NIV Noninvasive mechanical ventilationTNF Tumor necrosis factorCOVID-19Pneumonialcsh:Diseases of the respiratory systemCOVID-19 Drug TreatmentClinical trialCoronavirus030228 respiratory systemchemistrybusinessICTRP International Clinical Trials Registry PlatformPulmonology
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Effect of physical activity counseling on physical activity of older people in Finland (ISRCTN 07330512).

2011

SUMMARY The aim of this study was to describe the underlying theory and the implementation of a 2-year individualized physical activity counseling intervention and to evaluate whether benefits persisted 1.5 years after the intervention. The sample included 632 sedentary 75- to 81-year-old participants. Data were collected in 2003 –2005. The participants were randomly assigned to an intervention group and a control group. The intervention consisted of an individualized face-to-face meeting followed by telephone contacts every 4 months for 2 years, with the aim to increase participation in specific physical activities as well as to increase habitual physical activity. At the 2-year follow-up,…

CounselingMalemedicine.medical_specialtyAgingHealth (social science)Strength trainingHealth PromotionResidence CharacteristicsIntervention (counseling)Statistical significancemedicineAerobic exerciseHumansExerciseFinlandAgedAged 80 and overMotivationbusiness.industryIncidence (epidemiology)Public Health Environmental and Occupational HealthOdds ratioConfidence intervalSelf EfficacyPhysical therapyCalisthenicsFemalebusinessHealth promotion international
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Assessment of tobacco dependence curricula in Italian dental hygiene schools

2013

The aim of this study was to assess the level of tobacco dependence education offered by Italian dental hygiene programs. A fifty-question survey was mailed to the thirty-one active public and private dental hygiene programs in Italy during the 2008-09 academic year. The survey assessed faculty confidence in teaching tobacco treatment, which courses contained tobacco dependence content, the number of minutes spent on specific content areas, and the level of clinical competence that dental hygiene graduates should be able to demonstrate. Surveys were returned by sixteen programs for a response rate of 52 percent. Respondents indicated tobacco dependence education was included in clinic or cl…

Counselingmedicine.medical_specialtyTime FactorsAttitude of Health PersonnelSettore MED/50 - Scienze Tecniche Mediche ApplicateDentistrytobacco dependence tobacco treatment tobacco cessation dental hygiene education ItalySettore MED/28 - Malattie OdontostomatologicheIntervention (counseling)Oral and maxillofacial pathologyHumansMedicineCurriculumTobacco Use CessationResponse rate (survey)MotivationAcademic yearbusiness.industryTeachingTobacco Use DisorderGeneral MedicinePeriodontologymedicine.diseaseFacultySelf EfficacyTobacco Use Cessation DevicesQuitlineItalyPreventive DentistryFamily medicinePathology OralPeriodonticsClinical CompetenceCurriculumDental HygienistsEducational MeasurementBrief interventionbusiness
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W1113 Efficacy and Safety of Endoscopic Balloon Dilation of Symptomatic Intestinal Crohn's Disease Strictures

2009

Aim: To evaluate prospectively the clinical efficacy and safety of endoscopic hydrostatic balloon dilation in a consecutive cohort of symptomatic intestinal Crohn’s disease strictures. Methods: Between September 2003 and December 2008 we performed endoscopic balloon dilations in 37 Crohn’s disease patients with 39 intestinal symptomatic strictures (4 naive and 35 postoperative). Dilations were performed using a Rigiflex through-the-scope balloon. Clinical success rate was claimed if a patient remained asymptomatic and did not require surgery or further endoscopic dilation, following technical success. Actuarial curves of clinical, endoscopic (redilation) and surgical recurrence were obtaine…

Crohn's diseasemedicine.medical_specialtyHepatologybusiness.industryGastroenterologyDiseaseBalloonmedicine.diseaseAsymptomaticBalloon dilationsCohortBalloon dilationMedicineClinical efficacyRadiologymedicine.symptombusinessGastroenterology
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Country-specific differences of age stereotypes towards older hospital staff and their association with self-efficacy, work ability and mental well-b…

2020

To compare stereotypes towards older workers between hospital staff in Germany and Latvia and to analyse the relationship between those stereotypes and self-efficacy, subjective work ability and irritation.Cross-sectional study.In 2018, hospital staff, including nurses, physicians and other professions, of two German and three Latvian hospitals were asked to complete the standardized study questionnaire on subjective work ability, occupational self-efficacy, irritation and stereotypes towards older workers. In the latter scale older workers were defined as ≥45 years of age and the scale ranged from 27-135 whereby higher values reflect higher levels of positive stereotypes. To analyse the re…

Cross-sectional studySelf-conceptWork Capacity EvaluationContext (language use)German03 medical and health sciences0302 clinical medicineGermanySurveys and QuestionnairesHumans030212 general & internal medicineAssociation (psychology)General NursingSelf-efficacy030504 nursingMental healthlanguage.human_languageSelf EfficacyEuropePersonnel HospitalCross-Sectional StudiesPsychologieScale (social sciences)language0305 other medical sciencePsychologyClinical psychologyJournal of advanced nursingREFERENCES
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Mediation effect of self-efficacy in the relationship between neuroticism and L2 attainment

2019

This article investigates the role self-efficacy plays in the relationship between Neuroticism and foreign language attainment (operationalised as final grades and self-perceived foreign language skills). To date, the role of personality in foreign language learning has not been clearly specified; moreover, self-efficacy related to this domain has not received sufficient attention. For the purpose of the paper it was proposed that the negative relationship between Neuroticism and attainment can be explained by self-efficacy. The study’s informants consisted of 495 secondary grammar school students at the intermediate to upperintermediate levels of English proficiency. The results revealed t…

Cultural StudiesSelf-efficacy050101 languages & linguisticsLinguistics and Languagemedia_common.quotation_subject05 social sciencesForeign language050301 educationNeuroticismEducationDevelopmental psychologylanguage attainmentpersonalityMediationPersonality0501 psychology and cognitive sciencesneuroticismPsychology0503 educationself-efficacymedia_commonJournal of Multilingual and Multicultural Development
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Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia : a randomized controlled study

2018

Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100mm), and functional status was assessed by the Fibromyalgia Impact Questio…

DISORDERSsähkömagneettiset kentätsham treatmentWOMENmicrocirculationpulsed electromagnetic fieldmagneettihoitoCONTROLLED-TRIALEFFICACYverenkiertoDISEASEELECTRICAL NERVE-STIMULATIONIMPACT QUESTIONNAIRECLINICAL-TRIALkivunhoitoDOUBLE-BLINDINFLAMMATIONkrooninen kipufibromyalgia3111 Biomedicinechronic painmagnetotherapy
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The relationship between out-of-school sport participation and positive youth development

2012

Carreres-Ponsoda F, Escarti A, Cortell-Tormo JM, Fuster-Lloret V, Andreu-Cabrera E. The relationship between out-of-school sport participation and positive youth development. J. Hum. Sport Exerc. Vol. 7, No. 3, pp. 671-683, 2012. Despite growing evidence that participation in out-of-school activities and especially physical activity and sport programs facilitates positive development, little developmental research has been conducted on out-of-school sports programs compared with no participation in these activities or participation in other activities. Our study examined the participation of youth in out of school sport activities compared with participation in other out-of-school activitie…

Didáctica de la Expresión CorporalPROSOCIAL BEHAVIOR AND PERSONAL AND SOCIAL RESPONSIBILITY.educationPhysical activityProsocial behaviourPhysical Therapy Sports Therapy and RehabilitationDevelopmental researchOut of schoolDevelopmental psychologyOut of school sport activitiesPositive youth developmentEducación Física y Deportivalcsh:Sports medicineSelf-efficacyOUT OF SCHOOL SPORT ACTIVITIESbusiness.industryProsocial behavior and personal and social responsibilitySELF-EFFICACYPersonal and social responsibilityPersonal developmentProsocial behaviorSelf-efficacybusinessPositive Youth DevelopmentPsychologylcsh:RC1200-1245Social responsibilitySocial psychologyhuman activitiesPOSITIVE YOUTH DEVELOPMENTJournal of Human Sport and Exercise
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Effects of a Teaching Personal and Social Responsibility Model Intervention in Competitive Youth Sport

2021

The aim of this study was to implement the teaching personal and social responsibility (TPSR) model in a competitive context analyzing the differences between the intervention and the control group on personal and social responsibility, prosocial behaviors, and self-efficacy in youth soccer players. Participants were 34 youth soccer players between the ages of 14 and 16 years old (15.18 ± 0.72) divided into two different soccer teams of 17 members, corresponding to the control and intervention groups. The implementation of the TPSR model took place during 9 months, including initial and ongoing coach training (3 months), program implementation (three sessions per week lasting 90 min during …

Didáctica de la Expresión CorporalTeaching methodApplied psychologylcsh:BF1-990prosocial behaviors050109 social psychologyContext (language use)Sport competitionTeaching personal and social responsibility model03 medical and health sciences0302 clinical medicineIntervention (counseling)sport competitionPositive youth developmentEducación Física y DeportivaPsychology0501 psychology and cognitive sciencesGeneral Psychologyteaching personal and social responsibility modelOriginal Researchpositive youth developmentSelf-efficacybiologyAthletes05 social sciences030229 sport sciencesbiology.organism_classificationlcsh:PsychologyProsocial behaviorProsocial behaviorsPositive Youth DevelopmentPsychologySelf-efficacySocial responsibilityself-efficacyhuman activities
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Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial

2023

Background: The aim of this study is to compare the effects of %4 articaine and %2 lidocaine on inferior alveolar nerve block (IANB) for implant surgery in the posterior mandible.Material and Methods: The patients who have inserted implants in the posterior mandible were divided into 2 groups for IANB: lidocaine and articaine. VAS = visual analog scale, pain during surgery and injection, lip numb-ness time, mandibular canal-implant apex distance, age, gender, bone density, implant number, release incision, adjacent teeth, and duration of surgery were analyzed using t-test, Mann-Whitney U test, Spearman's coefficient, and, Pearson's chi-squared test. This trial followed the recommendations o…

Double-Blinddouble blind procedureEpinephrinemandibular nerveAnesthesia DentalExtractionlocal anesthetic agentCarticaineMandiblepain perceptionAdrenalineHypesthesiamapping reviewAnesthetic EfficacyDouble-Blind Methodle fortHumanshumanblood lossrandomized controlled trial (topic)Anesthetics LocalBuccal InfiltrationGeneral DentistryUNESCO:CIENCIAS MÉDICASRandomized Controlled Trials as Topicrelapsedental implantorthognathic surgery4-Percent ArticaineLidocainePulpitisNerve BlockMolarinfectionOtorhinolaryngologyarticaine2-Percent LidocaineSurgerylocal anesthesiadental anesthesiaMedicina Oral Patología Oral y Cirugia Bucal
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