Search results for "EFFICACY"
showing 10 items of 588 documents
Highly purified chondroitin sulfate: a literature review on clinical efficacy and pharmacoeconomic aspects in osteoarthritis treatment
2020
AbstractOsteoarthritis (OA) is the most prevalent musculoskeletal disease and a major cause of negative relevant outcomes, associated with an ever-increasing societal burden. Pharmaceutical-grade chondroitin sulfate (CS) was repeatedly reported to reduce pain and improve function in patients with OA. This article aims to review the evidence for the role of highly purified (hp) CS (Condrosulf®, IBSA) in the treatment of OA. We collected and reported evidence concerning (1) efficacy of hpCS 800 mg/day in the treatment of OA affecting the knee, hand and hip; (2) efficacy and safety of hpCS 1200 mg/day also in the oral gel formulation; (3) the safety profile of hpCS; (4) the difference of hpCS …
The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds.
2021
ABSTRACT With the increasing emergence of drug-resistant Mycobacterium tuberculosis strains, new and effective antibiotics against tuberculosis (TB) are urgently needed. However, the high frequency of poorly water-soluble compounds among hits in high-throughput drug screening campaigns is a major obstacle in drug discovery. Moreover, in vivo testing using conventional animal TB models, such as mice, is time consuming and costly, and represents a major bottleneck in lead compound discovery and development. Here, we report the use of the zebrafish embryo TB model for evaluating the in vivo toxicity and efficacy of five poorly water-soluble nitronaphthofuran derivatives, which were recently id…
The role of individual processes and learning environment in the prediction of grades in a sample of Norwegian students
2018
Student grades are traditionally used to evaluate academic achievement in higher education. A review of previous research indicates a relatively clear tendency to adopt either an individual or contextual approach in exploring this subject. The present study represents an attempt to simultaneously examine effects of individual variables and learning environment on academic achievements as measured in grades. The study adopts a quantitative approach and reports data collected from students enrolled in early childhood education in a mid-sized university in Norway. Results of a stepwise hierarchical regression demonstrate that individual variables (e.g. nonmandatory school attendance, self-effi…
Repensando la educación. Trayectoria y futuro de los sistemas educativos modernos
2019
Este artículo tiene por objetivo reflexionar sobre la doble condición de las reformas educativas requeridas en las sociedades avanzadas: como elemento de conocimiento político-sociológico y como acción reguladora social. A nivel metodológico se plantea una hermenéutica de las principales representaciones del cambio educativo, y se subraya que las reformas no deben subordinarse sólo a las necesidades sociológicas del momento. En esta línea, se exponen las demandas de cambio acaecidas a partir de PISA, así como las críticas que este modelo de evaluación ha recibido. Los principales resultados de los estudios internacionales analizados indican que comparar sistemas educativos y alumnado a part…
THE CREATIVITY AND RESILIENCE DEVELOPMENT PROJECT (CRDP) TO INVESTIGATE LEARNING PRACTICE IN THE USE OF ICT
2016
Much research has demonstrated that students' cognitive characteristics as general mental ability or prior level of achievement do explain a substantial proportion of the variance in subsequent achievement, but only more recently has research focused on relationships between cognitive characteristics of students and the process variables of classroom behaviour. In conceptualizations of teaching-learning situations, cognitive characteristics of students are seen as one cluster of determinants of the interactive and learning processes established in the classroom. The researchers suggest that flexibility is central to creative adaptation. The centrality of flexibility to creative adaptation a…
Self-efficacy and performance of the roundhouse kick in taekwondo
2014
[ES] El desarrollo de escalas de autoeficacia permite el análisis de las percepciones de los deportistas y el examen de la relación entre dichas percepciones y el rendimiento. El objetivo de este estudio fue (1) desarrollar una escala específica de autoeficacia para una tarea de taekwondo, la patada circular, y (2) analizar el rendimiento deportivo y su relación con los resultados de dos escalas de autoeficacia (específica y general) en función del género de los deportistas. En el estudio participaron 43 taekwondistas (33 hombres y 10 mujeres). Se administraron las escalas de autoeficacia Física (PSE) y Específica (RKSES). Los datos de rendimiento (fuerza de impacto y tiempo total de respue…
Students’ self-reported learning outcomes after a business start-up education program
2019
The aim of the present study is to examine the breadth of influence of a business plan-based entrepreneurship education. This task is implemented by examining students’ (n = 227) self-reported learning outcomes concerning entrepreneurial skills, attitudes and abilities after education. In addition to proposing a classification of the self-reported learning outcomes, this study explores how these outcomes are related to the background characteristics of those taking part in an education program, and of the companies involved. Based on this study, four main areas of self-reported learning outcomes were found: (i) working-life key skills, (ii) management skills, (iii) entrepreneurial empowerme…
What’s in a name : the effect of category labels on teachers’ beliefs.
2019
In this paper, we report an investigation of the possible influence on teachers’ essentialist thinking and efficacy beliefs of category labels used to describe children’s educational difficulties. A 2x2x2 counterbalanced design was employed in which primary school teachers in Finland and the UK were exposed to vignettes that portrayed a child exhibiting difficulties in one of two domains: either behaviour or reading. Vignettes were presented in two versions. In one, the child was labelled as having either ‘ADHD’ or ‘Dyslexia’; in the alternate condition, no such label was ascribed, descriptions were identical in all other respects. Participating teachers were presented with two vignettes, o…
Pas de titre traduit
2011
This research work adresses the prediction of success after a training scheme (success in university examination, integration of job seekers after a training session) on the basis of 1/ subjective indicators at the end of training: satisfaction or subjective learning and 2/ individuals' variables (self-efficacy, locus of control, self-esteem, optimism and core self-evaluation). Our results show that, compared to training evaluation models, subjective indicators at the end of training do not appear to be good predictors of success. In addition, if individuals' variables are sometimes predictable of success, this seems to be related to the mere fact that they represent high values in students…
La escritura expresiva en la orientación. Una metodología educativa para la construcción del proyecto de vida personal y profesional
2020
La scrittura espressiva adottata a scuola come strumento di autorientamento dell’adolescente di 17-18 anni non sostituisce l’intervento educativo dell’insegnante, piuttosto può considerarsi una tecnica efficace per raccogliere tutte le informazioni necessarie con cui formare, con il consenso dell’alunno e insieme a lui, un quadro esaustivo in cui includere lo stato attuale delle sue competenze, le sue attitudini, i suoi interessi, le sue motivazioni, la sua storia formativa, il suo profilo di personalità, i suoi limiti, nonché i suoi obiettivi e le modalità concrete con cui egli pensa di raggiungerli. Essa è pertanto un metodo educativo con cui gli studenti che si approssimano a svolgere gl…