Search results for "EFFICACY"
showing 10 items of 588 documents
Elotuzumab, lenalidomide, and dexamethasone as salvage therapy for patients with multiple myeloma: Italian, multicenter, retrospective clinical exper…
2020
No abstract available
Rituximab in primary Sjögren's syndrome: a ten-year journey
2014
Primary Sjögren's syndrome (pSS) is an autoimmune disorder affecting exocrine glands and characterized in most cases by a rather mild clinical picture. However, a subgroup of pSS patients experience systemic extraglandular involvement leading to a worsening of disease prognosis. Current therapeutic options for the treatment of pSS are mainly empirical, often translated by other autoimmune diseases, and recent systematic reviews have highlighted the lack of evidence-based recommendations for most of the drugs commonly employed in the spectrum of extraglandular involvement. Because of the well-established role of B-lymphocytes in the pathogenesis of pSS, a B-cell targeting therapy may repres…
From Planning to Management of Cultural Heritage Sites: Controversies and Conflicts Between Unesco WHL Management Plans and Local Spatial Planning in…
2014
The paper investigates the relationship between the preservation of cultural heritage and planning in UNESCO World Heritage List (WHL) sites, with special reference to the relation be- tween Management Plans and other (local and regional) planning instruments and policies able to influence the promotion of sustainable and responsible development. This will be explored through a case study related to South-Eastern Sicilian UNESCO sites (in particular Syracuse). The analysis of this case study will point out the challenge of integrating different management and planning regimes - which mainly refer to a performative model - in a (still) very conformative planning sys- tem. The paper will show…
Transformational leadership and depressive symptoms among employees : mediating factors
2014
Purpose– The purpose of this paper is to examine whether the link between transformational leadership and depressive symptoms among employees is mediated by such personal resources as occupational self-efficacy, perceived meaningfulness of the work, and work-related rumination.Design/methodology/approach– The study was conducted using questionnaires among 557 Finnish municipal employees in various occupations. The statistical analysis was based on structural equation modeling. A multiple mediation model enabled us to investigate the specific indirect effects of each mediator. Model comparison was applied to ascertain whether the mediation should be considered as full or partial.Findings– Re…
Clima scolastico e variabili soggettive dei docenti di scuola secondaria
2015
The theme of our research is understanding why many aspects of school climate are interrelated and how such relations influence subsequent scholastic functioning. The research is oriented towards the determination of personal and environmental factors that provide to explain several aspects of the construct. We administered a test battery to analyze: Scholastic Climate; Personal and Collective Efficacy; Organizational Commitment, Involvement, and Job Satisfaction. Findings confirm the constant influence of personal efficacy on determining of the level of job involvement and satisfaction. If teachers’ personal efficacy convictions play a significant role on stamp their scholastic perceptions…
Efficacy of swm appliance in the expression of first-, second- and third-order information in Class I and Class II
2019
Background To assess the efficacy of a multibracket appliance-Straight-wire Mirabella (SWM) prescription-in terms of achieving the ideal first-, second- and third-order values proposed by Andrews. Material and methods A total sample of 46 Caucasian subjects was divided into two groups: 23 with class I malocclusion (Group 1), and 23 with class II malocclusion (Group 2). The treatment protocol involved fixed multibracket appliances-SWM prescription-for both groups, with the addition of class II elastics for Group 2. Values for ΔU1-PP, ΔIMPA, in-out, tip and torque were measured on digital scans, and the results obtained were compared with the ideal values proposed by Andrews. Results Statisti…
Det er tungt å bære sekken, men det er tyngre å bære på unyttige tanker : En kvalitativ studie om på hvilken måte friluftsliv og opphold i naturen ka…
2017
Masteroppgave folkehelsevitenskap ME516 - Universitetet i Agder 2017 Introduction: As a result of the growth in mental illnesses and the industrial society, there is an increased need for a place where humans can reconnect and find peace. Science shows that almost one out of four grown up Norwegians has a mental disorder, and that physical activity, especially by spending time in nature, can contribute to the recovery. To accommodate these challenges, I believe that science can offer a better understanding on how we can facilitate for health promotion accompanied with nature. Objective and key question: The purpose of this study is to get a better and holistic understanding on how the natur…
Scaffolding for motivation by parents, and child homework motivations and emotions: Effects of a training programme
2018
Background and aims Based on the principles of scaffolding for motivation and on the assumptions of self-determination theory, two studies aimed to assess the role played by perceived parental autonomy-supportive scaffolding on child homework autonomous motivation, self-efficacy, affect, and engagement. Samples and results The results of Study 1, which involved 122 parents and their children, showed that the higher the parental autonomous motivation, the more their children perceived them as autonomy-supportive while scaffolding for motivation, and hence developed autonomous motivation, self-efficacy, and engagement in homework. In Study 2, 37 parents were involved in a four-session trainin…
Child consumption of fruit and vegetables: the roles of child cognitions and parental feeding practices
2011
AbstractObjectiveTo examine the roles of child cognitions and parental feeding practices in explaining child intentions and behaviour regarding fruit and vegetable consumption.DesignCross-sectional surveys among pre-adolescent children and their parents.SettingThe child questionnaire included measures of fruit and vegetable consumption and cognitions regarding fruit and vegetable consumption as postulated by the Attitude–Social Influence–Self-Efficacy (ASE) model. The parent questionnaire included measures of parental feeding practices derived from the Comprehensive Feeding Practices Questionnaire (CFPQ).SubjectsIn total, 963 parents and 796 students in grades 5 and 6 from eighteen schools …