Search results for "EIV"

showing 10 items of 833 documents

Validity of the Seattle Heart Failure Model after heart failure hospitalization.

2019

Abstract Aims Heart failure hospitalization is a sentinel event associated with increased mortality risk. Whether long‐term heart failure risk models such as the Seattle Heart Failure Model (SHFM) accurately assess risk in the post‐hospital setting is unknown. Methods and results The SHFM was applied to a cohort of 2242 consecutive patients (50% women; mean age 73) on discharge after acute heart failure hospitalization and analysed for the primary endpoint of all‐cause mortality. Model discrimination and calibration were assessed. Direct patient‐level comparison between our study cohort and the original SHFM cohorts was also performed to confirm and quantify the degree and extent of increas…

Malemedicine.medical_specialty030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineRisk FactorsSeattle Heart Failure ModelInternal medicineOriginal Research ArticlesClinical endpointmedicineHumansIn patient030212 general & internal medicineOriginal Research ArticleHospital dischargeMortality riskAgedAged 80 and overHeart FailureModels StatisticalReceiver operating characteristicbusiness.industryReproducibility of ResultsAcute heart failureMean ageAfter dischargeMiddle Agedmedicine.diseaseHospitalizationHeart failureAmbulatoryCohortCardiologyFemaleCardiology and Cardiovascular MedicinebusinessESC heart failure
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Differentiation of benign and malignant lymph nodes in pediatric patients on ferumoxytol-enhanced PET/MRI.

2019

The composition of lymph nodes in pediatric patients is different from that in adults. Most notably, normal lymph nodes in children contain less macrophages. Therefore, previously described biodistributions of iron oxide nanoparticles in benign and malignant lymph nodes of adult patients may not apply to children. The purpose of our study was to evaluate if the iron supplement ferumoxytol improves the differentiation of benign and malignant lymph nodes in pediatric cancer patients on 18F-FDG PET/MRI. Methods: We conducted a prospective clinical trial from May 2015 to December 2018 to investigate the value of ferumoxytol nanoparticles for staging of children with cancer with 18F-FDG PET/MRI.…

Malemedicine.medical_specialtyAdolescentAnemiaMRI contrast agentMedicine (miscellaneous)030218 nuclear medicine & medical imagingLesioncancer imaging03 medical and health sciences0302 clinical medicineFluorodeoxyglucose F18lymph nodesNeoplasmsferumoxytolmedicineHumansProspective StudiesChildPharmacology Toxicology and Pharmaceutics (miscellaneous)Lymph nodeReceiver operating characteristicbusiness.industryCell Differentiationmedicine.diseasePediatric cancerMagnetic Resonance ImagingFerrosoferric Oxide3. Good healthFerumoxytolmedicine.anatomical_structurePET/MRI030220 oncology & carcinogenesisPositron-Emission TomographyNanoparticlesFemaleRadiologyLymphmedicine.symptomRadiopharmaceuticalsbusinessResearch PaperTheranostics
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Slackline Training in Children with Spastic Cerebral Palsy: A Randomized Clinical Trial

2020

Objective: To assess whether a slackline intervention program improves postural control in children/adolescents with spastic cerebral palsy (CP). Design: Randomized controlled trial. Setting: Patients&rsquo

Malemedicine.medical_specialtyAdolescentHealth Toxicology and MutagenesisMovementSignificant groupMotor DisordersTerapéuticalcsh:Medicineneuro-disabilityArticlelaw.inventionrehabilitation03 medical and health sciencesTratamiento médico0302 clinical medicineSpastic cerebral palsyRandomized controlled triallawSpasticMedicineHumansChildPostural BalanceMotor skillRating of perceived exertionIntervention programexerciseSistema nerviosobusiness.industryElectromyographyCerebral PalsyPosturographylcsh:RPublic Health Environmental and Occupational HealthResistance Training030229 sport sciencesmedicine.diseaseEnfermedadesNiños paralíticos cerebralesTreatment OutcomeMotor SkillsMuscle SpasticityPhysical therapynon-conventional balance therapyFemalebusiness030217 neurology & neurosurgery
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Kayaking performance is altered in mentally fatigued young elite athletes

2019

Background The present study aimed to assess the impact of 60 min of a cognitive demanding task inducing mental fatigue (Stroop) on kayaking performance in young elite athletes. The second objective was to elucidate the effect of mental fatigue on performance in a population of young under-17 elite athletes of national. Methods Thirteen under-17 elite kayakers completed 60 min of an incongruent Stroop color-word test, or the equivalent time in a control condition in a cross-over study design. Afterwards, participants completed a 2000 m kayaking time trial in which power output, stroke rate and time at the end of 400, 800, 1200, 1600 and 2000 m were recorded. Physiological and perceptual mea…

Malemedicine.medical_specialtyAdolescentPopulationPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicineTime trialHeart RateHeart ratemedicineHumansOrthopedics and Sports MedicineeducationWater SportsRating of perceived exertioneducation.field_of_studyCross-Over StudiesCognition030229 sport sciencesMental FatigueCrossover studyTest (assessment)AthletesStroop TestPhysical therapyFemalePsychology030217 neurology & neurosurgeryStroop effectThe Journal of Sports Medicine and Physical Fitness
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Health literacy and participation in sports club activities among adolescents

2017

Aims: The aim of this research was to compare the levels of perceived health literacy among adolescents who do or do not participate in sports club activities. Organized sport club activities reach a high proportion of adolescents, and have the potential to contribute to the development of their health literacy. Methods: The cross-sectional data on health literacy among school children in Finland (aged 13 and 15, n=3852) were measured, as a part of the Health Behaviour in School-Aged Children (HBSC) study, using the Health Literacy for School-aged Children (HLSAC) instrument. Sports club participation and its association with health literacy were examined in relation to age, gender, family…

Malemedicine.medical_specialtyAdolescentmedia_common.quotation_subjecteducationPhysical activityHealth literacyliteracynuorisofamily affluenceaffluencephysical activenessLiteracyPerceived healthsports clubs03 medical and health sciences0302 clinical medicinenuoretmedicineHumans030212 general & internal medicineadolescentsFinlandmedia_commonMedical educationyouthAcademic SuccessPublic Health Environmental and Occupational Healthta3141health030229 sport sciencesGeneral MedicineCross-Sectional Studiesschool achievementsPhysical therapyFemaleCluburheiluseuratPsychologyhuman activitiesterveyshealth literacyfyysinen aktiivisuusSportsScandinavian Journal of Public Health
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Concurrent validation of the OMNI-Resistance Exercise Scale of perceived exertion with elastic bands in the elderly.

2018

Purpose:\ud To examine the concurrent validity of the OMNI-Resistance Exercise Scale of perceived exertion using elastic bands in elder population.\ud \ud Methods:\ud Twenty-six participants performed three separate sets of 15 repetitions (low- medium- and high-intensity) for 4 different exercises (2 for the upper-limb and 2 for the lower limb), over two different testing sessions. The criterion variables were heart rate and applied force (average and maximum). In addition to these dependent variables, the active muscle and overall body OMNI-RES for elastic bands scores were collected at the end of each repetition.\ud \ud Results:\ud Significant differences in heart rate, applied force and …

Malemedicine.medical_specialtyAgingScale (ratio)Intraclass correlationConcurrent validityPopulationPhysical ExertionPerceived exertion030204 cardiovascular system & hematologyBiochemistry03 medical and health sciences0302 clinical medicineEndocrinologyPhysical medicine and rehabilitationHeart RateHeart rateTask Performance and AnalysisGeneticsmedicineHumanseducationMuscle SkeletalMolecular BiologyMathematicsAgedRating of perceived exertioneducation.field_of_study030229 sport sciencesCell BiologyMiddle AgedQPCross-Sectional StudiesExercise intensityExercise TestFemalePerceptionPsychomotor PerformanceExperimental gerontology
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Blood Infusion and the Risk of Haemorrhage in Patients Undergoing Cardiac Surgery with Extracorporeal Circulation.

2016

Purpose: Patients undergoing cardiac surgery with extracorporeal circulation (ECC) frequently present haemorrhages as a complication associated with high morbidity and mortality. One of the factors that influences this risk is the volume of blood infused during surgery. The objective of this study was to determine the optimal volume of autologous blood that can be processed during cardiac surgery with ECC. We also determined the number of salvaged red blood cells to be reinfused into the patient in order to minimize the risk of haemorrhage in the postoperative period. Methods: This was an observational retrospective cross-sectional study performed in 162 ECC cardiac surgery patients. Data r…

Malemedicine.medical_specialtyAutologous bloodBlood volumeHemorrhageHigh morbidityRisk FactorsMedicineHumansIn patientPostoperative PeriodInfusion PumpsAgedRetrospective StudiesPharmacologyBlood VolumeReceiver operating characteristicbusiness.industryExtracorporeal circulationThoracic Surgical ProceduresSurgeryCardiac surgeryCross-Sectional StudiesROC CurveAnesthesiaFemaleCardiology and Cardiovascular MedicineComplicationbusinessErythrocyte TransfusionCurrent vascular pharmacology
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A Sequential Algorithm Combining ADAPT and Liver Stiffness Can Stage Metabolic-Associated Fatty Liver Disease in Hospital-Based and Primary Care Pati…

2020

INTRODUCTION Metabolic-associated fatty liver disease is common, with fibrosis the major determinant of adverse outcomes. Population-based screening tools with high diagnostic accuracy for the staging of fibrosis are lacking. METHODS Three independent cohorts, 2 with both liver biopsy and liver stiffness measurements (LSMs, n = 254 and 65) and a population sample (n = 713), were studied. The performance of a recently developed noninvasive algorithm (ADAPT [age, diabetes, PRO-C3 and platelets panel]) as well as aspartate aminotransferase-to-platelet ratio index, fibrosis-4, nonalcoholic fatty liver disease fibrosis score, and LSM was used to stage patients for significant (≥F2) and advanced …

Malemedicine.medical_specialtyBiopsyPopulationGastroenterology03 medical and health sciences0302 clinical medicineFibrosisNon-alcoholic Fatty Liver DiseasePredictive Value of TestsDiabetes mellitusInternal medicineNonalcoholic fatty liver diseasemedicineDiabetes MellitusHumansAspartate Aminotransferaseseducationeducation.field_of_studyHepatologymedicine.diagnostic_testReceiver operating characteristicbusiness.industryPlatelet CountFatty liverGastroenterologyAge FactorsOdds ratioMiddle Agedmedicine.diseaseCollagen Type III030220 oncology & carcinogenesisLiver biopsyElasticity Imaging Techniques030211 gastroenterology & hepatologyFemalebusinessAlgorithmsBiomarkersThe American journal of gastroenterology
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Early Improvement and Serum Concentrations of Citalopram to Predict Antidepressant Drug Response of Patients with Major Depression

2013

Post hoc analyses of clinical trials have shown that early improvement around day 14 is highly predictive for later response. More- over, evidence has been given that suffi ciently high concentrations of antidepressant drugs in blood are required to attain response. In this study, we determined cut-off levels for citalo- pram serum concentrations and clinical improve- ment during the early phase of treatment to predict later response and the predictive power of these measures either alone or in combination. Methods: Inpatients with depressive disorder according to ICD-10 who received citalopram were included. Psychopathology was assessed by the 17-item Hamilton Depression (HAMD-17) rating s…

Malemedicine.medical_specialtyCitalopramCitalopramSensitivity and SpecificityPredictive Value of TestsRating scaleInternal medicinemedicineHumansPharmacology (medical)Depression (differential diagnoses)Depressive Disorder MajorReceiver operating characteristicGeneral MedicineOdds ratioMiddle AgedAntidepressive AgentsClinical trialPsychiatry and Mental healthAnesthesiaAntidepressantFemalePsychologyPsychopathologymedicine.drugPharmacopsychiatry
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Global Geriatric Assessment and In-Hospital Bleeding Risk in Elderly Patients with Acute Coronary Syndromes: Insights from the LONGEVO-SCA Registry.

2018

Background: Bleeding risk scores have shown a limited predictive ability in elderly patients with acute coronary syndromes (ACS). No study explored the role of a comprehensive geriatric assessment to predict in-hospital bleeding in this clinical setting. Methods: The prospective multicentre LONGEVO-SCA registry included 532 unselected patients with non-ST segment elevation ACS (NSTEACS) aged 80 years or older. Comorbidity (Charlson index), frailty (FRAIL scale), disability (Barthel index and Lawton-Brody index), cognitive status (Pfeiffer test) and nutritional risk (mini nutritional assessment-short form test) were assessed during hospitalization. CRUSADE score was prospectively calculated …

Malemedicine.medical_specialtyFrail ElderlyGerontologíaEnfermedad cardiovascularHemorrhageComorbidityfrailty030204 cardiovascular system & hematologyLogistic regressionRisk Assessmentelderly03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansValoración geriátricaSíndrome coronario agudoacute coronary syndromes030212 general & internal medicineProspective StudiesRegistriesAcute Coronary SyndromeProspective cohort studyGeriatric AssessmentAgedAged 80 and overInpatientsbiologyReceiver operating characteristicbusiness.industryGeriatric assessmentHematologyOdds ratiomedicine.diseasebleedingComorbidityTroponinTroponincomorbidityArea Under Curvebiology.proteinFemaleRisk assessmentbusiness
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