Search results for "ELA"

showing 9 items of 33899 documents

Monotherapy with indacaterol once daily reduces the rate of exacerbations in patients with moderate-to-severe COPD: Post-hoc pooled analysis of 6 mon…

2014

Summary Background In patients with COPD, exacerbations are associated with poor quality of life and may shorten survival. Prevention of exacerbations is, therefore, a key objective in COPD management. Indacaterol, a once-daily ultra-long-acting β 2 -agonist, has been shown to reduce exacerbations in various studies. This pooled analysis evaluated the effect of indacaterol on exacerbations versus placebo. Methods Six-month data were pooled from three randomized, double-blind, and placebo-controlled studies: indacaterol 300 μg versus placebo (1 year); indacaterol 150 μg and 300 μg versus placebo (6 months); and indacaterol 150 μg versus placebo (6 months). All treatments were administered on…

β2-agonistPulmonary and Respiratory Medicinemedicine.medical_specialtyExacerbationKaplan-Meier EstimateQuinolonesPlaceboDrug Administration SchedulePooled analysisExacerbationsPulmonary Disease Chronic ObstructiveFEV1/FVC ratioDouble-Blind MethodForced Expiratory VolumeInternal medicineHumansCOPDMedicineAdrenergic beta-2 Receptor AgonistsRandomized Controlled Trials as TopicIndacaterolCOPDDose-Response Relationship Drugbusiness.industryMinimal clinically important differenceHazard ratiomedicine.diseaseConfidence intervalBronchodilator AgentsClinical Trials Phase III as TopicAnesthesiaIndansIndacaterolbusinessBronchodilatormedicine.drugRespiratory Medicine
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Evidence against the wobbling nature of low-spin bands in 135Pr

2021

International audience; The electromagnetic character of the ΔI=1 transitions connecting the 1- to 0-phonon and the 2- to 1-phonon wobbling bands should be dominated by an E2 component, due to the collective motion of the entire nuclear charge. In the present work it is shown, based on combined angular correlation and linear polarization measurements, that the mixing ratios of all analyzed connecting transitions between low-lying bands in 135Pr interpreted as 0-, 1-, and 2-phonon wobbling bands, have absolute values smaller than one. This indicates predominant M1 magnetic character, which is incompatible with the proposed wobbling nature. All experimental observables are instead in good agr…

γγγ-coincidencesNuclear and High Energy Physics010308 nuclear & particles physicsPhysicsQC1-999FOS: Physical sciences-coincidences[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]nucl-ex01 natural sciencesParticle rotor modelAngular correlationsspin (kvanttimekaniikka)0103 physical sciencesWobbling bandsNuclear Physics - ExperimentNuclear Experiment (nucl-ex)ydinfysiikka010306 general physicsNuclear Experiment
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Analysis of infiltrating γδ T cells in cutaneous melanoma: a hypothetic crosstalk for new immunotherapy

2022

Introduction: Melanoma is one of the most frequently occurring skin cancer and remains an important cause of mortality mainly in Caucasian populations. In clinical practice, the standard treatment for localized melanoma is surgical resection but for metastatic melanoma, few treatments are available, where chemo and radio-therapies are rarely indicated. Immunotherapy has revolutionized the management of metastatic melanoma that, as in others tumors, uses your body's own immune system to help fight cancer. Therapies targeting the immune checkpoint molecules have achieved objective responses in melanoma. Several receptors and/or ligands, such as PDL1, PD-1 and CTLA-4, have been identified as i…

γδ T lymphocytes.melanomaimmunotherapyimmunocheckpoint molecule
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On continua whose hyperspace of subcontinua is σ-locally connected

1999

Abstract We provide a structural characterization of all continua X whose hyperspace C ( X ) of all subcontinua is the countable union of Peano continua. Applying this result we prove that there exists a uniformly path connected continuum X with no continuous mapping from C ( X ) onto X.

σ-local connectednessConnected spacePure mathematicsContinuum (topology)Mathematical analysisCharacterization (mathematics)Hyperspace of subcontinuaσ-relative local connectednessHyperspaceLocal connectednessPeano axiomsContinuumCountable setGeometry and TopologyLocal connectednessRelative local connectednessMathematicsTopology and its Applications
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GEOCHEMISTRY OF THE GAS MANIFESTATIONS OF GREECE: METHANE AND LIGHT HYDROCARBONS

2017

Το σύνθετο γεωδυναμικό καθεστώς της Ελλάδας πηγάζει από την πολύπλοκη γεωλογική της ιστορία, η οποία χαρακτηρίζεται από έντονη σεισμική δραστηριότητα και ενισχυμένη γεωθερμική βαθμίδα. Αυτή η δραστηριότητα σε συνδυασμό με το ενεργό ηφαιστειακό τόξο, ευνοεί την ύπαρξη πολλών εκπομπών αερίων, με αποτέλεσμα την κατηγοριοποίηση σε CO2-, N2- και CH4-αέρια, ανάλογα με το επικρατών είδος. Η παρούσα εργασία επικεντρώνεται στο μεθάνιο και τους ελαφρούς υδρογονάνθρακες (C2-C6) με σκοπό τον προσδιορισμό της προέλευσή τους. Οι συγκεντρώσεις του CH4 (<2 έως 915,200 μmol/mol) και η ισοτοπική του αναλογία (δ13C -79.8 έως +16.9 ‰, δD -298 έως +264‰) καλύπτουν ένα ευρύ φάσμα τιμών, που υποδεικνύει διαφορ…

υδροθερμικά αέρια010504 meteorology & atmospheric sciencesπροέλευση υδρογονανθράκωνMineralogyΕλληνική περιοχή010502 geochemistry & geophysics01 natural sciencesMedicinal chemistryLight hydrocarbonsSettore GEO/08 - Geochimica E Vulcanologiahydrothermal gasesεκπομπές ψυχρών αερίωνHellenic territoryorigin of hydrocarbon gasesHellenic territory hydrothermal gases cold gas emissions origin of hydrocarbon gasesMaterials Chemistrycold gas emissionsGeology0105 earth and related environmental sciences
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Вклад Мирдзы Аболы (1923-2007) в расширение латышско-белорусских литературных связей

2018

Абола Мирдзаархивное наследиеarchival heritageBelarusian-Latvian-Belarusian dictionary:HUMANITIES and RELIGION [Research Subject Categories]Abola Myrdzaлатвийские-белорусские литературные связилатвiйска-беларускiя лiтаратурныя сувязiархiуная спадчынаАбала Мiрдзабеларуска-латышска-беларускi слоунiкLatvian-Belarusian literary relationsбелорусско-латышско-белорусский словарь
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Beam-induced and cosmic-ray backgrounds observed in the ATLAS detector during the LHC 2012 proton-proton running period

2016

This paper discusses various observations on beam-induced and cosmic-ray backgrounds in the ATLAS detector during the LHC 2012 proton-proton run. Building on published results based on 2011 data, the correlations between background and residual pressure of the beam vacuum are revisited. Ghost charge evolution over 2012 and its role for backgrounds are evaluated. New methods to monitor ghost charge with beam-gas rates are presented and observations of LHC abort gap population by ghost charge are discussed in detail. Fake jets from colliding bunches and from ghost charge are analysed with improved methods, showing that ghost charge in individual radio-frequency buckets of the LHC can be resol…

Большой адронный коллайдерbackground [beam]Physics::Instrumentation and DetectorsMonte Carlo methodPerformance of high energy physics detectorJet (particle physics)01 natural sciencesHigh Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)pressureSubatomic Physicsscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Instrumentationпротон-протонные столкновенияQCMathematical PhysicsPhysicseducation.field_of_studyPerformance of high energy physics detectorsLarge Hadron ColliderSettore FIS/01 - Fisica SperimentaleBeam-intensity monitors; Beam-line instrumentation (beam position and profile monitors; Bunch length monitors); Data analysis; Performance of high energy physics detectors; Instrumentation; Mathematical PhysicsData analysiMonte Carlo [numerical calculations]ATLASbuildingsBunchesCERN LHC CollBeam-intensity monitorBeam-line instrumentation (beam position and profile monitorComputingMethodologies_DOCUMENTANDTEXTPROCESSINGcolliding beams [p p]Particle Physics - ExperimentParticle physicsCiências Naturais::Ciências Físicas530 PhysicsAstrophysics::High Energy Astrophysical PhenomenaPopulation:Ciências Físicas [Ciências Naturais]Beam-line instrumentation (beam position and profile monitorsData analysisFOS: Physical sciencesgapCosmic ray530Bunch length monitors)Nuclear physicsATLAS LHC High Energy Physics510 Mathematics0103 physical sciencesBeam-line instrumentation (beam position and profile monitors;; beam-intensity monitors; bunch length monitors); Data analysis;; Performance of High Energy Physics Detectors; LEPHigh Energy Physicsddc:610010306 general physicseducationMuonScience & Technologycosmic radiation [muon]010308 nuclear & particles physicsFísicaLEPBeam-intensity monitorsghostcorrelationExperimental High Energy PhysicsBeam-line instrumentation (beam position and profile monitors; beam-intensity monitors; bunch length monitors); Data analysis; Performance of High Energy Physics DetectorsBeam-line instrumentation (beam position and profile monitors; beam-intensity monitors; bunch length monitors)Physics::Accelerator PhysicsPerformance of High Energy Physics DetectorsATLAS детекторBeam (structure)experimental resultsbeam-line instrumentation
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LEBENSWELT ALS PRAKTISCHER HORIZONT

2017

СтатьяпредставляетоценкугуссерлевскогопонятияLebensweltнаосновеегопозднихрукописей, посвященныхгенетическомуанализу. Размышлениеопонятиижизненногомиранацеленонато, чтобыоценитьфеноменологическийвкладвфилософскиеспорыза HORIZON 6 (2) 2017 47пределамиразногласийреализма, натурализмаисубъективизма. Статьяначинаетсясрассмотренияидеи «универсальнойкорреляции», акцентируятемсамымэгологическуюфигуру «Ich-kann» (Я-могу) каксобственногокандидатанато, чтобысоставитьконституциюжизненногомира. Встатьеутверждается, чтоконститутивнаяактивность «Я-могу» отвечаетзавнутреннююартикуляциюмножествачастныхмиров (Sonderwelten) впределахобъемлющегожизненногомира. Такоеотношениемеждумирами, центрированнымиинтересо…

Гуссерль Я-могу конституция корреляция жизненныймир феноменологическаяэтика особенныймир традиция ответственностьSettore M-FIL/03 - Filosofia MoraleHusserl I-can constitution correlation life-world phenomenological ethics particular world tradition responsibility
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Translation ‘going social’? Challenges to the (Ivory) Tower of Babel

2010

The discussion of “turns” or “paradigmatic shifts” which we can witness in the last few years in Translation Studies undoubtedly testifies to the discipline’s increasing establishment and recognition within the scientific community and of the increasing practice of a transdisciplinary research. These shifts also include what has been called the “sociological turn”, which comprises the cluster of questions dealing not only with the networks of agents and agencies and the interplay of their power relations, but also the social discursive practices which mould the translation process and which decisively affect the strategies of a text to be translated. This paper seeks to foreground some of t…

“Sociological turn”EthicsLinguistics and LanguageUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASTraducció -- Aspectes socialsSocial perspectiveProcess (engineering)Traducción e InterpretaciónMethodologyPower relationsSociological turnWitnessLanguage and LinguisticsEducationEpistemologyTranslation sociology; Sociological turn; Methodology; Ethics; Translation and activism:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Translation studiesTranslation sociologyIvory towerSociologyAffect (linguistics)Social scienceTranslation and activism
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