Search results for "EMAST"

Functional and energetic consequences of climate change on a predatory whelk

2017

Abstract The increasing rise in sea surface temperature caused by human activities currently represents the major threat to biodiversity and natural food webs. In this study we used the Lessepsian mussel Brachidontes pharaonis, one of the most recent invaders of the Mediterranean Sea, as a model to investigate the effect of a novel prey and a chronic increase in temperatures on functional parameters of local consumers, compared to the native mytilid species Mytilaster minimus. In particular we focused on the whelk Stramonita haemastoma, a widespread Mediterranean intertidal predator that actively preys on bivalves, barnacles and limpets, by studying the direct effects of such multiple stres…

Paradoxical attenuation of leukocyte rolling in response to ischemia- reperfusion and extracorporeal blood circulation in inflamed tissue.

2005

In contrast to acute preparations such as the exteriorized mesentery or the cremaster muscle, chronically instrumented chamber models allow one to study the microcirculation under “physiological” conditions, i.e., in the absence of trauma-induced leukocyte rolling along the venular endothelium. To underscore the importance of studying the naive microcirculation, we implanted titanium dorsal skinfold chambers in hamsters and used intravital fluorescence microscopy to study venular leukocyte rolling in response to ischemia-reperfusion injury or extracorporeal blood circulation. The experiments were performed in chambers that fulfilled all well-established criteria for a physiological microcir…

The Centetostoma scabriculum complex—a group of three cryptic species (Arachnida: Opiliones: Nemastomatidae)

2011

Nemastoma scabriculum Simon, 1879 turned out to be a group of three closely related species of the Pyrenees in SW Europe (France and Spain). Though the species are similar in general habit they can easily be recognized by external morphology (structure of the apophysis of male chelicerae) and male genital morphology (penial structure). For Nemastoma scabriculum Simon, 1879 sensu stricto a lectotype is designated. The synonymous Nemastoma ventalloi Mello-Leitao, 1936 is considered to be a distinct species and is re-described. The third species of the group is described as new, Centetostoma juberthiei sp. n. Though partly sympatric in their restricted Pyrenean area, the individual species are…

<p><strong><em>Sinostoma</em> <em>yunnanicum</em>, the first nemastomatine harvestman in China (Arachnida: Opilio…

2016

The easternmost Nemastomatinae species, Sinostoma yunnanicum n. gen., n. sp., from northern Yunnan, China is described. It extends the geographic distribution of Nemastomatinae by roughly 3000 km southeastwards. Within Nemastomatinae Sinostoma displays plesiomorphic characters, including the long, basic bulb of the truncus shaft and the extremely short glans of penis, armed with short robust spines. Sinostoma may represent a relict line in the early evolution of nemastomatine harvestmen.

Feinstruktur der Cheliceren-Dr�se von Nemastoma dentigerum Canestrini (Opiliones, Nemastomatidae)

1973

1. Nemastoma dentigerum Canestrini besitzt als sekundares mannliches Geschlechtsmerkmal eine Apophyse auf dem ersten Chelicerenglied, die eine Druse enthalt. 2. Die einzelnen Drusenzellen schliesen sich jeweils zu Dreiergruppen zusammen, deren distales Ende immer von 3 Hullzellen umfast wird. Diese 6 Zellen bilden eine funktionelle Einheit innerhalb des komplexen Drusenorgans. Jede Drusenzelle gliedert sich in 3 Abschnitte: 1. in den basalen kernhaltigen Teil, 2. in den mittleren sehr langen Drusenzellschlauch und 3. in den distalen Kopf mit Mikrovilli-Becher. 3. An der Sekretion beteiligen sich 2 Zelltypen: die 3 Drusenzellen und die innere Hullzelle (H1). Das Sekret beider Zelltypen gelan…

No evidence of EMAST in whole genome sequencing data from 248 colorectal cancers.

2021

Microsatellite instability (MSI) is caused by defective DNA mismatch repair (MMR), and manifests as accumulation of small insertions and deletions (indels) in short tandem repeats of the genome. Another form of repeat instability, elevated microsatellite alterations at selected tetranucleotide repeats (EMAST), has been suggested to occur in 50% to 60% of colorectal cancer (CRC), of which approximately one quarter are accounted for by MSI. Unlike for MSI, the criteria for defining EMAST is not consensual. EMAST CRCs have been suggested to form a distinct subset of CRCs that has been linked to a higher tumor stage, chronic inflammation, and poor prognosis. EMAST CRCs not exhibiting MSI have b…

Gluing the ‘unwettable’: soil-dwelling harvestmen use viscoelastic fluids for capturing springtails

2014

Gluing can be a highly efficient mechanism of prey capture, as it should require less complex sensory–muscular feedback. Whereas it is well known in insects, this mechanism is much less studied in arachnids, except spiders. Soil-dwelling harvestmen (Opiliones, Nemastomatidae) bear drumstick-like glandular hairs (clavate setae) at their pedipalps, which were previously hypothesized to be sticky and used in prey capture. However, clear evidence for this was lacking to date. Using high-speed videography, we found that the harvestman Mitostoma chrysomelas was able to capture fast-moving springtails (Collembola) just by a slight touch of the pedipalp. Adhesion of single clavate setae increased p…

Comparative efficacy of levocetirizine, desloratadine, clemastine, kvifenadine and sekvifenadine on histamine prick test induced weal reaction, blood…

2007

Myogenic effects enhance norepinephrine constriction: Inhibition by nitric oxide and felodipine

1998

Myogenic effects enhance norepinephrine constriction: Inhibition by nitric oxide and felodipine. Myogenic, pressure-induced vasoconstriction may amplify the effects of circulating vasoconstrictors. Through intravital microscopy in cremaster arterioles (31 to 115 μm diameter), the relative contribution of myogenic responses (MR) to norepinephrine (NE)-induced constriction and the inhibitor potency of nitric oxide (NO) or a Ca2+ entry blocker (CEB), felodipine (F), were examined. In 24 anesthetized hamsters, a vessel occluder was placed around the aorta to control cremaster vessel inflow pressure (IP). NE infusion increased blood pressure (by 50 ± 2mm Hg) and induced significant constriction …

Local consumers are the first line to control biological invasions: a case of study with the whelk Stramonita haemastoma (Gastropoda: Muricidae)

2016

The increasing spread of invasive species in the Mediterranean Sea determines several alterations in local food webs, changing the feeding habits of native organisms. The whelk Stramonita haemastoma is a widespread Mediterranean gastropod that consumes bivalves, barnacles and limpets. Previous studies showed a shift in its diet from the bivalve Mytilaster minimus to the invasive mussel Brachidontes pharaonis, presumably due to a higher energy gain. Here we tested whelks’ preference among natives and a novel prey, calculating the profitability ratio, and integrating those results with biochemical analysis on prey tissues and the routine metabolism of the whelks. Further, we used the scaled f…