Search results for "EMC"
showing 10 items of 369 documents
Results of a Phase I-II Pilot Study with Intravescical Gemcitabine in Superficial Bladder Cancer (Ta-T1)
2005
To study the ablative activity of intravescical gemcitabine against superficial transitional cell carcinoma of the bladder at different doses and concentrations. Methods Twenty-seven patients were treated with intravescical gemcitabine after transurethral resection, during which one to three papillary marker lesions were left unresected. Starting 14 days after transurethral resection, six gemcitabine instillations were given at weekly intervals. Gemcitabine, diluted in 50 mL of saline solution and maintained for 2 hr, was given at a dose of 500, 1000 and 2000 mg in groups of nine patients each. A complete response (CR) was defined as negative cutologycystoscopy and biopsy findings. Results…
Management of refractory angina: an update.
2020
Abstract Despite the use of anti-anginal drugs and/or percutaneous coronary interventions (PCI) or coronary artery bypass grafting, the proportion of patients with coronary artery disease who have daily or weekly angina ranges from 2% to 24%. Refractory angina refers to long-lasting symptoms (for >3 months) due to established reversible ischaemia, which cannot be controlled by escalating medical therapy with the use of 2nd- and 3rd-line pharmacological agents, bypass grafting, or stenting. While there is uncertain prognostic benefit, the treatment of refractory angina is important to improve the quality of life of the patients affected. This review focuses on conventional pharmacolog…
Erythritol-enriched powder and oral biofilm regrowth on dental implants: an in vitro study.
2021
Background Peri-implant mucositis and peri-implantitis are the main biological complications associated with dental implants. Since most authors agree that bacteria play a major etiological role, the main aims of this study were to determine if a formulation of erythritol and chlorhexidine applied with an air polishing system inhibits biofilm regrowth over dental implants and to compare the decontamination capacity of this therapy with that of mechanical removal by saline and gauze. Material and Methods A multispecies biofilm (P. gingivalis, A. actinomycetemcomitans, F. nucleatum, A. naeslundii, V. parvula and S. oralis) was grown for 14 days on 52 dental implants in an artificial mouth. Th…
Microbial Leakage at the Implant-Abutment Connection Due to Implant Insertion Maneuvers: Cross-Sectional Study 5 Years Postloading in Healthy Patient…
2015
The aim of this study was to test if stress on the prosthetic connection during insertion maneuvers can induce micro-warping at the implant connection. From September 2011 to July 2013, patients with implants loaded for at least 5 years that were placed with 2 different insertion implant mounters—MP (conventional) and ME (mountless)—were selected from all of those who had received dental implant therapy in the past and were attending routine check-up or spontaneous visits during the study period. Samples were obtained from inside the connection and the abutment surface using absorbent sterile paper tips. Quantitative real-time polymerase chain reaction was performed for total bacterial coun…
Calibration of the underground muon detector of the Pierre Auger Observatory
2021
To obtain direct measurements of the muon content of extensive air showers with energy above $10^{16.5}$ eV, the Pierre Auger Observatory is currently being equipped with an underground muon detector (UMD), consisting of 219 10 $\mathrm{m^2}$-modules, each segmented into 64 scintillators coupled to silicon photomultipliers (SiPMs). Direct access to the shower muon content allows for the study of both of the composition of primary cosmic rays and of high-energy hadronic interactions in the forward direction. As the muon density can vary between tens of muons per m$^2$ close to the intersection of the shower axis with the ground to much less than one per m$^2$ when far away, the necessary bro…
Copper and Palladium NWs for Hydrogen Peroxide detection
2018
H2O2 is a wide used chemical in different field, like in paper and textile industries and pharmaceutical applications. Furthermore, H2O2 concentration in human body is related to glucose concentration because the reaction between glucose and glucosidase produce hydrogen peroxide [1] . Moreover, is used as a biomarker of oxidative stress, being an oxidative specie [2] . For all these reasons, researcher all over the world are working to develop new and novel strategies for in situ, non-invasive and fast detection of this chemical. One of these fields concern the electrochemical sensors, that are sensors with an electrical (current, potential, impedance) output. The surface area the electrode…
Niemieckie dokumenty katechetyczne ostatniego ćwierćwiecza
2017
Artykuł jest próbą syntetycznego przedstawienia zasadniczych idei, które zostały wyrażone w niemieckich dokumentach katechetycznych ostatniego ćwierćwiecza. Po opublikowaniu w 1997 r. przez Kongregację ds. Duchowieństwa Dyrektorium ogólnego o katechizacji w Niemczech nie pojawiło się narodowe dyrektorium katechetyczne, które uwzględniałoby specyfikę wychowania religijnego w tym kraju i wskazywało zasadnicze kierunki współczesnej katechezy. Niemieccy biskupi podejmowali jednak wielokrotnie zagadnienia związane z wychowaniem religijnym. Wśród tych wypowiedzi na szczególną uwagę zasługują cztery dokumenty: 1. Zeit zur Aussaat. Missionarisch Kirche sein (Czas na siew. Być Kościołem misyjnym) z …
A novel intrinsically disordered outer membrane lipoprotein ofAggregatibacter actinomycetemcomitansbinds various cytokines and plays a role in biofil…
2017
Intrinsically disordered proteins (IDPs) do not have a well-defined and stable 3-dimensional fold. Some IDPs can function as either transient or permanent binders of other proteins and may interact with an array of ligands by adopting different conformations. A novel outer membrane lipoprotein, bacterial interleukin receptor I (BilRI) of the opportunistic oral pathogen Aggregatibacter actinomycetemcomitans binds a key gatekeeper proinflammatory cytokine interleukin (IL)-1b. Because the amino acid sequence of the novel lipoprotein resembles that of fibrinogen binder A of Haemophilus ducreyi, BilRI could have the potential to bind other proteins, such as host matrix proteins. However, from th…
Trzydzieści lat stosunków polsko-niemieckich w cieniu historii (1990–2020)
2020
Celem artykułu jest ukazanie dominacji historii w stosunkach polsko-niemieckich od przełomu lat 80. i 90. XX w. po czasy współczesne. Trzydzieści minionych lat podzielono na cztery podokresy i zaprezentowano dominujące w nich kwestie historyczne. Wybrane przykłady problemów z przeszłości i debaty, jakie toczyły i toczą się nadal na ich temat, świadczą dobitnie o ich ogromnym znaczeniu dla rozwoju relacji między Polakami a Niemcami. Szczególną uwagę poświęcono kwestii budowy w Niemczech pomnika polskich ofi ar II wojny światowej.
Egzekwowanie stosowania przepisów RODO przez organy nadzorcze wybranych krajów Unii Europejskiej
2021
Założeniem niniejszej pracy jest chęć przybliżenia i analizy, jak w poszczególnych krajach członkowskich Unii Europejskiej (tj. w Niemczech i Francji) doregulowane zostały przepisy Rozporządzenia ogólnego o ochronie danych osobowych, ze szczególnym uwzględnieniem zasad funkcjonowania organów nadzorczych i, w konsekwencji powyższego wykazanie, czy poziom ochrony danych osobowych podmiotów danych jest spójny we wszystkich krajach członkowskich