Search results for "EMU"

showing 10 items of 2247 documents

SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

2017

AbstractBiogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteoporotic phenotype. An association analysis of SNPs located in pri-miRNA sequences with bone mineral density (BMD) was performed in the OSTEOMED2 cohort (n = 2183). Functional studies were performed for assessing the role of BMD-associated miRNAs in bone cells. Two SNPs, rs6430498 in the miR-3679 and rs12512664 in the miR-4274, were significantly associated with femoral neck BMD. Further, we…

0301 basic medicineconformation:Diseases::Wounds and Injuries::Fractures Bone::Hip Fractures [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings]Polimorfismo de nucleótido simpleGene ExpressionboneOsteoblastosDensidad ósea:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort StudiesGene Frequencysingle nucleotide polymorphismBone DensityBone cellOssosgeneticsFracturas osteoporóticasCells CulturedGeneticsBone mineralMicroARNsMultidisciplinarymicroRNAbiologyQalleleR:Diseases::Wounds and Injuries::Fractures Bone::Osteoporotic Fractures [Medical Subject Headings]clinical trialMiddle Agedcohort analysisPhenotypeHumanosFenotipmedicine.anatomical_structureCancellous BoneosteoblastMedicine:Diseases::Musculoskeletal Diseases::Bone Diseases [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]:Anatomy::Cells::Connective Tissue Cells::Osteoblasts [Medical Subject Headings]AlelosFenotipomusculoskeletal diseasesmedicine.medical_specialtyGenotypeScienceSingle-nucleotide polymorphismBiologychemistryPolymorphism Single NucleotideArticleBone and Bones:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Cancellous Bone [Medical Subject Headings]03 medical and health sciencesCalcification PhysiologicInternal medicinemicroRNAmedicineHumanshumanproceduresAllele:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings]AllelesFemoral neckGenetic associationAgedcell culture:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]OsteoblastsEnfermedades óseasFracturas de caderaComputational BiologyCuello femoral:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Antisense Elements (Genetics)::RNA Antisense::MicroRNAs [Medical Subject Headings]MicroRNAs030104 developmental biologyEndocrinologymulticenter studybone mineralizationNucleic Acid ConformationOsteoporosispathology:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur::Femur Neck [Medical Subject Headings]TranscriptomemetabolismGenotipoFractures
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Impact of reducing fat, salt and sugar in commercial foods on consumer acceptability and willingness to pay in real tasting conditions: A home experi…

2017

International audience; Decreasing obesity or cardiovascular disease can be achieved by eating healthier foods with reduced contents of fat, salt and sugar. However, these ingredients have a significant impact on the sensory quality of the food products that contain these ingredients, especially cooked sausage, chorizo, dry sausage, cheese and muffins. In this study, consumer appreciation of these five commercialized products (non reformulated versions) and their respective reformulated versions with reduced contents of salt, fat and sugar was tested. An original home experiment was performed to assess consumer appreciation in natural consumption conditions. The experiment was divided into …

0301 basic medicinelikingPleasantness[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionmedia_common.quotation_subjecthedonic scoresmultiple emulsionssystemcheeseyogurt03 medical and health sciences0404 agricultural biotechnologyWillingness to payévaluation sensorielleconsentement à payer du consommateurFood and NutritionWillingness to payQuality (business)fiber informationFood scienceSugarpreferencesConsumer behaviourmedia_commonMathematicsSensory evaluation2. Zero hungerConsumption (economics)030109 nutrition & dieteticsNutrition and Dieteticscomportement des consommateursConsumer behaviourHome experiment04 agricultural and veterinary sciencesclassementstability040401 food scienceReservation priceAlimentation et NutritionagrémentRankingWine tastingStore brandhome experiment;ranking;consumer behaviour;sensory evaluation;pleasantness;willingness to pay[SDV.AEN]Life Sciences [q-bio]/Food and NutritionAutre (Sciences du Vivant)expectationsFood ScienceFood Quality and Preference
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Chromosomal distribution of interstitial telomeric sequences in nine neotropical primates (Platyrrhini): possible implications in evolution and phylo…

2016

To localize interstitial telomeric sequences (ITSs) and to test whether their pattern of distribution could be linked to chromosomal evolution, we hybridized telomeric sequence probes (peptide nucleic acid, PNA) on metaphases of New World monkeys: Callithrix argentata, Callithrix jacchus, Cebuella pygmaea, Saguinus oedipus, Saimiri sciureus, Aotus lemurinus griseimembra, Aotus nancymaae (Cebidae), Lagothrix lagotricha (Atelidae) and Callicebus moloch (Pithecidae), characterized by a rapid radiation and a high rate of chromosomal rearrangements. Our analysis of the probe signal localization allowed us to show in all the species analysed, as normally, the telomeric location at the terminal en…

0301 basic medicineowl monkeyChromosomes; genome evolution; owl monkeys; phylogeny; telomeric sequences; Ecology Evolution Behavior and Systematics; Molecular Biology; Animal Science and Zoology; GeneticsZoologyPlatyrrhiniAtelidaegenome evolutionSettore BIO/08 - AntropologiaChromosomephylogeny03 medical and health sciencesCebidaeGeneticsAotus lemurinus griseimembraMolecular BiologyEcology Evolution Behavior and SystematicsAotus nancymaaetelomeric sequencebiologySaimiri sciureusbiology.organism_classificationMolecular biologyCallithrixSaguinus oedipusEcology Evolution Behavior and Systematic030104 developmental biologyAnimal Science and Zoology
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A solution of the minimum-time velocity planning problem based on lattice theory

2018

For a vehicle on an assigned path, we find the minimum-time speed law that satisfies kinematic and dynamic constraints, related to maximum speed and maximum tangential and transversal acceleration. We present a necessary and sufficient condition for the feasibility of the problem and a simple operator, based on the solution of two ordinary differential equations, which computes the optimal solution. Theoretically, we show that the problem feasible set, if not empty, is a lattice, whose supremum element corresponds to the optimal solution.

0303 health sciences0209 industrial biotechnologyComputer Networks and CommunicationsApplied MathematicsMinimum timeFeasible region02 engineering and technologyKinematicsInfimum and supremum03 medical and health sciences020901 industrial engineering & automationControl and Systems EngineeringOptimization and Control (math.OC)Lattice (order)Ordinary differential equationSignal ProcessingFOS: MathematicsApplied mathematicsMathematics - Optimization and Control030304 developmental biologyMathematics
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Role of aroma–matrix interactions on perception of structured emulsions

2011

The impact of the composition of spreads on in vivo aroma release and aroma perception was investigated using online proton transfer reaction mass spectrometry (PTR-MS) and sensory methodologies. Consumption of model products spread on bread induced a significant increase in aroma release and better discrimination in aroma perception, compared to when the product was tasted pure from a spoon. Dynamic release of a series of 10 aroma compounds was slower with the increase in solid fat content, and the quantity decreased when proteins were added. Sensory ranking of model products mostly confirmed the release results.

030309 nutrition & dieteticsFat contentmedia_common.quotation_subject[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionMatrix (chemical analysis)03 medical and health sciences0404 agricultural biotechnologyPerceptionFood scienceAromaProton-transfer-reaction mass spectrometryComputingMilieux_MISCELLANEOUSmedia_commonemulsion0303 health sciencesChromatographybiologyChemistryfood and beveragesflavour perception04 agricultural and veterinary sciencesbiology.organism_classification040401 food science[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionaroma releaseEmulsion[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Effect of iron chelates on oil–water interface, stabilized by milk proteins: The role of phosphate groups and pH. Prediction of iron transfer from aq…

2010

International audience; Iron incorporated into food systems induces oxidation and precipitation. The consequences are reduced bioavailability and a functional modification of other food components such as proteins. The iron-chelates such as ferrous bisglycinate represent a possibility to avoid side effects, since the iron is protected. The aim of this study is to investigate the effects of iron-chelates compounds on the properties of an oil/water interface stabilized by caseinate or β-lacotoglobulin, under environmental conditions at 20 °C. Analyses were performed using dynamic drop tensiometry during 5000 s. The aqueous bulk phase is an imidazole/acetate buffer (0.1 M), containing 0.4 × 10…

030309 nutrition & dieteticsGeneral Chemical EngineeringInorganic chemistryIron fortificationSurface tension03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyOil-in-water emulsion[SDV.IDA]Life Sciences [q-bio]/Food engineeringChelationBeta-lactoglobulin2. Zero hunger0303 health sciencesAqueous solutionChromatographybiologyChemistryAqueous two-phase systemEmulsifying activityProteins04 agricultural and veterinary sciencesGeneral ChemistryPhosphate040401 food scienceEmulsionPhosphate groupsbiology.proteinChemical stabilityFood ScienceFood Hydrocolloids
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Ensuring Diverse User Experiences and Accessibility While Developing the TeSLA e-Assessment System

2019

The TeSLA project, with its new, innovative approaches for e-assessment, offers a great possibility for increasing the educational equality and making higher education studies available for all. It has been estimated that 10–15% of students in higher education institutions have some disabilities or special educational needs. At online universities or in online programmes, the number is even higher. These numbers emphasise the importance of the universal design for learning as a leading principle while developing the digital learning environments and e-assessment procedures. In this chapter, we describe the key elements of ensuring the accessibility of the TeSLA e-assessment system during th…

030506 rehabilitationKnowledge managementHigher educationkoulutusteknologiaoppiminenComputer sciencearviointimenetelmätstudent with special educational needs and disabilities (SEND student)luottamuksellisuus03 medical and health sciencesTeSLA ProjectvammaisuusUser experience designerityisopetusverkko-opiskeluuser experienceetäopetusComputingMilieux_COMPUTERSANDEDUCATIONerityiskasvatusverkkoarviointiTeSLA-projektiDigital learninge-assessmentetäopiskeluspecial educational needskäytettävyysbusiness.industry4. Education05 social sciences050301 educationUniversal Design for LearningUsabilityaccessibilityusabilityE-assessmente-arviointidisabilitysaavutettavuusKey (cryptography)Special educational needskäyttäjäkokemus0305 other medical sciencebusiness0503 educationarviointi
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‘I just want someone to rub some life into them!’ : the lived experience of impaired sensation in the feet related to multiple sclerosis

2021

Background: Impaired sensation in the feet is a commonly reported symptom experienced by people with multiple sclerosis. Aim: To explore the lived experiences of people living with multiple sclerosis-related impaired sensation in their feet. Method: Five open, unstructured interviews were analysed using a descriptive phenomenological method developed by Amedeo Giorgi. Findings: The essential structure of the research phenomenon consists of six key constituents: sense of heightened awareness of body sensation; sense of changed relationship to the feet; sense of changed participation in daily life; sense of the self with multiple sclerosis; sense of the meaning of interaction with others; and…

030506 rehabilitationMultiple sclerosisLived experiencefenomenologiapuutuminenmedicine.diseasetuntoaistikoettu terveys03 medical and health sciences0302 clinical medicineMS-tautiSensationmedicinekehontuntemusNeurology (clinical)Descriptive phenomenology0305 other medical sciencePsychology030217 neurology & neurosurgeryGeneral NursingClinical psychology
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Developing E-Authentication for E-Assessment : Diversity of Students Testing the System in Higher Education

2020

Sähköinen tunnistautuminen on yksi keskeisistä teemoista verkko-opetuksessa, -opiskelussa ja - arvioinnissa. Tämän tutkimuksen tarkoituksena oli tutkia opiskeluunsa erityistä tukea tarvitsevien yliopisto-opiskelijoiden käyttökokemuksia kehitteillä olevasta sähköisestä tunnistautumisjärjestelmästä. Erityistä huomiota kehittämistyössä kiinnitettiin tunnistautumisen saavutettavuuteen. Kaikkiaan 15 opiskelijaa testasi TeSLA-projektin osana kehitettyä tunnistautumisjärjestelmää, johon kuului kasvojentunnistus, äänentunnistus, näppäilyntunnistus, tekstityylianalyysi ja plagioinnin tunnistus. Opiskelijat täyttivät esi- ja jälkikyselylomakkeet sekä osallistuivat henkilökohtaisiin haastatteluihin. T…

030506 rehabilitationerilaiset oppijatHigher educationmedia_common.quotation_subjectInternet privacykorkeakouluopetus03 medical and health sciencesspecial educational needs and disabilities (SEND)ComputingMilieux_COMPUTERSANDEDUCATIONsähköinen tunnistaminenverkko-opetuse-assessmentmedia_commonbusiness.industry4. Education05 social sciences050301 educationTeSLA systemverkko-oppiminenAuthentication (law)accessibilityE-assessmentsaavutettavuuse-authenticationhigher educationkäyttäjäkokemus0305 other medical sciencePsychologybusiness0503 educationDiversity (politics)
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Physiotherapists’ conceptions of movement awareness– A phenomenographic study

2021

The phenomenon of movement awareness requires more attention to make it explicit in physiotherapy. The aim of this study was to explore the variation in physiotherapists’ conceptions of movement quality, focusing on movement awareness. The informants were 15 physiotherapists from a variety of physiotherapy fields. We collected data through two group interviews and used the phenomenographic method to analyze them. Four themes emerged from the data: 1) Being in contact with one’s own moving body; 2) Increased awareness of movement experiences; 3) Interrelationship between physiotherapist and patient; and 4) Better understanding of movement awareness. These themes varied by four descriptive ca…

030506 rehabilitationphenomenographyAttitude of Health PersonnelMovementApplied psychologyPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicinePhenomenonphysiotherapistkäsityksetkehontuntemusHumansLearningMovement qualityPhenomenographyfysioterapeutitPhysical Therapy ModalitiesQualitative ResearchMovement (music)Moving bodykehonhallintaliikeVariety (cybernetics)Physical Therapistsmovement qualityconceptionfenomenografia0305 other medical sciencePsychologyreflektio030217 neurology & neurosurgeryreflectionmovement awarenessPhysiotherapy Theory and Practice
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