Search results for "EPA"

showing 10 items of 8995 documents

Anticoagulation with low-molecular-weight heparin (dalteparin) in plasmapheresis therapy: initial experience

2006

BACKGROUND:  In contrast to other extracorporeal treatments no established regime exists for anticoagulation with low-molecular-weight heparin (LMWH) in plasmapheresis therapy. A study was conducted to investigate whether LMWH (dalteparin-Na) is suitable as an effective anticoagulant in plasmapheresis therapy. STUDY DESIGN AND METHODS:  Eleven patients with autoimmune neurological diseases and the necessity for a plasmapheresis therapy were enrolled. A capillary membrane filter was used. A total of 2000 mL of human plasma was isovolumetrically exchanged per plasmapheresis cycle. The anticoagulation was accomplished with a single bolus of LMWH (dalteparin) of 80 to 90 IU per kg of body weigh…

AdultDalteparinmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentImmunologyLow molecular weight heparinGuillain-Barre SyndromeExtracorporealBolus (medicine)Myasthenia GravismedicineHumansImmunology and AllergyMonitoring PhysiologicDalteparin sodiumbusiness.industryAnticoagulantAnticoagulantsPlasmapheresisHematologyHeparinSurgerySingle bolusAnesthesiaPlasmapheresisbusinessmedicine.drugTransfusion
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Enhancement pattern of small hepatocellular carcinoma (HCC) at contrast-enhanced US (CEUS), MDCT, and MRI: intermodality agreement and comparison of …

2012

OBJECTIVE:To evaluate agreement between contrast-enhanced ultrasound (CEUS), multi-detector row computed tomography (MDCT) and magnetic resonance imaging (MRI) for the assessment of typical and atypical enhancement patterns of small hepatocellular carcinoma (HCC); and to compare diagnostic sensitivity of 2005 and 2010 American Association for the Study of Liver Diseases (AASLD) guidelines. MATERIALS AND METHODS: Between January 2008 and December 2009, we included cirrhotic patients with newly diagnosed 10-20 mm HCC imaged at two contrast-enhanced imaging techniques among CEUS, MDCT, and MRI. Dynamic studies were reviewed by two radiologists to assess enhancement pattern. Percentage of cases…

AdultDiagnostic ImagingMalemedicine.medical_specialtyCarcinoma HepatocellularContrast MediaEnhancement patternSensitivity and SpecificityImaging modalitiesTumor enhancementMcNemar's testmedicineHumansRadiology Nuclear Medicine and imagingAgedAged 80 and overmedicine.diagnostic_testbusiness.industryLiver NeoplasmsUltrasoundReproducibility of ResultsMagnetic resonance imagingGeneral MedicineMiddle Agedmedicine.diseaseUnited Statessmall hepatocellular carcinomaItalyHepatocellular carcinomaPractice Guidelines as TopicFemaleRadiologybusinesscontrast-enhanced ultrasoundContrast-enhanced ultrasound
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Imaging findings of liver resection using a bipolar radiofrequency electrosurgical device—Initial observations

2010

Abstract Objective To assess contrast-enhanced US (CEUS), computed tomography (CT) and magnetic resonance (MR) imaging findings and serial changes of the treated area at follow-up in patients who underwent liver resection using a bipolar radiofrequency electrosurgical device. Methods Imaging findings of 27 patients with resected hepatocellular carcinomas (HCCs) ( n  = 24) and metastases ( n  = 3) (mean size: 2.6 cm), were retrospectively evaluated. Two readers assessed: the (a) presence, (b) thickness, (c) shape and (d) echogenicity (CEUS)/attenuation (CT)/signal intensity (MR imaging) at coagulated site and the (e) presence of residual tumor of the bipolar radiofrequency electrosurgical de…

AdultDiagnostic ImagingMalemedicine.medical_specialtyCarcinoma HepatocellularRadiofrequency ablationElectrosurgeryPilot ProjectsHepatocellular carcinoma Liver metastases Liver resection Radiofrequency ablation Coagulative necrosislaw.inventionlawmedicineHepatectomyHumansRadiology Nuclear Medicine and imagingAgedmedicine.diagnostic_testbusiness.industryLiver NeoplasmsEchogenicityMagnetic resonance imagingEquipment DesignGeneral MedicineMiddle Agedmedicine.diseasePeripheralEquipment Failure AnalysisTreatment OutcomeCoagulative necrosisHepatocellular carcinomaCatheter AblationResection marginELECTROSURGICAL DEVICEFemaleRadiologybusinessEuropean Journal of Radiology
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Cost analysis of recall strategies for non-invasive diagnosis of small hepatocellular carcinoma.

2010

Abstract Background Which is the least expensive recall policy for nodules in the cirrhotic liver remains unclear. Aim Aim of the study was to analyze the costs of different recall diagnostic strategies of hepatocellular carcinoma (HCC) on cirrhosis on a real series of patients. Methods 75 consecutive small liver nodules (10–30 mm) detected at conventional ultrasonography in 60 patients with cirrhosis were submitted to contrast-enhanced ultrasound, computed tomography and gadolinium-magnetic resonance imaging with a final diagnosis established according to the latest guidelines which include different strategies for nodules 10–19 mm or ≥20 mm. The actual costs required to fully characterise…

AdultDiagnostic ImagingMalemedicine.medical_specialtyCirrhosisCarcinoma HepatocellularCost effectivenessHCC diagnosismedicineHumansProspective StudiesAgedAged 80 and overHepatologyRecallbusiness.industryNon invasiveUltrasoundLiver NeoplasmsGastroenterologyNodule (medicine)Middle Agedmedicine.diseaseHepatocellular carcinomaCost analysisCosts and Cost AnalysisFemaleRadiologymedicine.symptombusiness
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Elevated Pressure in the Dorsal Part of Pancreas Divisum

1988

Summary In 6 patients with upper abdominal pain of unknown origin presenting with pancreas divisum, the pressure in the pancreatic duct was measured via the minor papilla into which in these patients the main part of the pancreatic duct system drains. For comparison intraductal manometry via the major papilla (papilla of Vater) was performed in 8 patients with normal pancreatic duct system. The pressure in the pancreatic duct of the control group was 10.5 ± 0.9 mm Hg. whereas in the patients with pancreas divisum it was 23.7 ± 1.3 mm Hg. The results demonstrate that in patients with pancreas divisum, intraductal pressure may be largely increased even in the fasting state.

AdultDorsummedicine.medical_specialtyManometryEndocrinology Diabetes and MetabolismGastroenterologyEndocrinologyInternal medicineInternal MedicinemedicineHumansIn patientPancreasPancreatic ductPancreas divisumHepatologybusiness.industryGeneral surgeryPancreatic Ductsmedicine.diseaseMajor duodenal papillamedicine.anatomical_structurePancreatitisUpper abdominal painChronic DiseasePancreatitisBile DuctsbusinessPancreasPancreas
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Studies on the Australia antigen

1972

Australia antigen typings on leprosy and control samples from West Bengal (India) and Angola (Africa) showed a considerably higher incidence of this antigen in lepromatous lepers as compared with other types of this disease resp. controls. By this the findings of Blumberg et al. (1967) in the Philippines could be confirmed. The possible reasons for this observations are discussed.

AdultElectrophoresisAdolescentBlack PeopleIndiaBiologyWhite PeopleHepatitis B AntigensAntigenLeprosyGeneticsmedicineHumansChildGenetics (clinical)AgedHepatitisLepromatous leprosyIncidence (epidemiology)Middle AgedHepatitis Bmedicine.diseaseGenetics PopulationPhenotypeAngolaImmunologyWest bengalLeprosyHuman Genetics
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Blood rheology during chemotherapy in patients with ovarian cancer.

1998

The use of platinum based chemotherapy in ovarian malignancy and other cancer types is known to be associated with deep vein thrombosis. In a prospective study of 47 patients with ovarian cancer of International Federation of Gynecology and Obstetrics stage Ib-IV, serial rheological parameters were determined (plasma viscosity, red blood cell aggregation under conditions of stasis and low shear) in addition to hemoglobin, hematocrit, leukocytes, platelets, and fibrinogen. At the same time the incidence of deep vein thrombosis was recorded before, during six cycles of first line cisplatinum/epirubicin/cyclophosphamide chemotherapy, and 2 months thereafter (two-months check-up). Only six pati…

AdultErythrocyte Aggregationmedicine.medical_specialtymedicine.drug_classDeep veinBlood viscosityVenographyLow molecular weight heparinAntineoplastic AgentsHematocritGastroenterologyHemoglobinsLeukocyte CountInternal medicineAntineoplastic Combined Chemotherapy ProtocolsMedicineHumansProspective StudiesVeinCyclophosphamideAgedEpirubicinOvarian Neoplasmsmedicine.diagnostic_testbusiness.industryPlatelet CountFibrinogenHematologyHeparin Low-Molecular-WeightMiddle AgedThrombophlebitismedicine.diseaseBlood ViscosityThrombosisSurgerymedicine.anatomical_structureHematocritHemorheologyFemaleCisplatinbusinessEpirubicinmedicine.drugThrombosis research
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Fluke egg characteristics for the diagnosis of human and animal fascioliasis by Fasciola hepatica and F. gigantica

2009

In trematodiases, shape and size of the fluke eggs shed with faeces are crucial diagnostic features because of their typically reduced intraspecific variability. In fascioliasis, the usual diagnosis during the biliary stage of infection is based on the classification of eggs found in stools, duodenal contents or bile. The aim of the present study is to validate the identification of Fasciola species based on the shape and size of eggs shed by humans, characterizing their morphometric traits using a computer image analysis system (CIAS). The influence of both the geographical location and of the host (human and livestock) has been analysed. Coprological studies were carried out in fasciolias…

AdultFascioliasisPathologymedicine.medical_specialtyGeorgiaAdolescentSwineEggsVeterinary (miscellaneous)HelminthiasisZoologyParasitic disease diagnosisFecesYoung AdultHepaticaPeruparasitic diseasesImage Processing Computer-AssistedmedicineAnimalsHumansFasciola hepaticaHelminthsChildMicroscopySheepFasciolabiologyEquidaeFasciola hepaticabiology.organism_classificationmedicine.diseaseFasciolaInfectious DiseasesVietnamParasitologyInsect ScienceCattleEgyptParasitologyTrematodaActa Tropica
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Evolution of indeterminate hepatocellular nodules at Gd-EOB-DPTA-enhanced MRI in cirrhotic patients

2018

To retrospectively analyze the evolution of indeterminate hepatocellular nodules in cirrhotic patients on serial Gd-EOB-DPTA-enhanced MRI, and to identify predictors of HCC development. This IRB approved study included 33 cirrhotic patients with 69 indeterminate hepatocellular nodules (mean diameter 1.1 cm) at baseline Gd-EOB-DPTA-enhanced MRI and a Gd-EOB-DPTA-enhanced-MRI follow-up of at least 2 years. Two radiologists evaluated size and signal intensity of each nodule at baseline and follow-up. Age, cirrhosis etiology, and HCC history were recorded. Data were compared between nodules that became HCCs at follow-up (HCC) and those that did not (no-HCC). On follow-up, 5/69 nodules became HC…

AdultGadolinium DTPALiver CirrhosisMalemedicine.medical_specialtyCirrhosisCarcinoma HepatocellularContrast MediaCirrhosis; Gd-EOB-DTPA; HCC; Indeterminate hepatocellular nodule; Liver MRIGastroenterology030218 nuclear medicine & medical imagingLiver MRI03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingHCCneoplasmsNeuroradiologyAgedRetrospective StudiesAged 80 and overCirrhosimedicine.diagnostic_testbusiness.industryLiver NeoplasmsIndeterminate hepatocellular noduleNodule (medicine)Magnetic resonance imagingGeneral MedicineHCCSMiddle Agedmedicine.diseaseMagnetic Resonance Imagingdigestive system diseasesGd-EOB-DTPA030220 oncology & carcinogenesisPredictive value of testsEtiologyFemalemedicine.symptomIndeterminatebusiness
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Value of texture analysis on gadoxetic acid–enhanced MRI for differentiating hepatocellular adenoma from focal nodular hyperplasia

2019

OBJECTIVE. The objective of our study was to assess the diagnostic performance of texture analysis (TA) on gadoxetic acid-enhanced MR images for differentiation of hepatocellular adenoma (HCA) from focal nodular hyperplasia (FNH).MATERIALS AND METHODS. This study included 40 patients (39 women and one man) with 51 HCAs and 28 patients (27 women and one man) with 32 FNH lesions. All lesions were histologically proven with preoperative MRI performed with gadoxetic acid. Two readers reviewed all the imaging sequences to assess the qualitative MRI characteristics. The T2-weighted fast spin-echo, hepatic arterial phase (HAP), and hepatobiliary phase (HBP) sequences were used for TA. Textural fea…

AdultGadolinium DTPAMaleGadoxetic acidCarcinoma Hepatocellulargenetic structuresAdolescenthepatocellular adenomaContrast MediaSensitivity and Specificity030218 nuclear medicine & medical imagingAdenoma Liver CellDiagnosis Differential03 medical and health sciences0302 clinical medicineImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingTexture (crystalline)Agedfocal nodular hyperplasiabusiness.industryLiver NeoplasmsFocal nodular hyperplasiatexture analysiGeneral MedicineHepatocellular adenomaMiddle Agedmedicine.diseaseImage EnhancementMagnetic Resonance Imagingdigestive system diseases030220 oncology & carcinogenesisFemaleMr imagesNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaValue (mathematics)medicine.drugMRI
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